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Methyl 3-benzenesulfonaMidobenzoate

CAS No.
107922-46-3
Chemical Name:
Methyl 3-benzenesulfonaMidobenzoate
Synonyms
Methyl 3-benzenesulfonaMidobenzoate;methyl 3-(phenylsulfonamido)benzoate;3-(phenylsulfonylacylamino)methyl benzoate;Benzoic acid, 3-[(phenylsulfonyl)amino]-, methyl ester
CBNumber:
CB82679428
Molecular Formula:
C14H13NO4S
Molecular Weight:
291.32
MDL Number:
MFCD00121318
MOL File:
107922-46-3.mol
MSDS File:
SDS
Last updated:2026-05-28 05:55:24

Methyl 3-benzenesulfonaMidobenzoate Properties

Boiling point 448.1±47.0 °C(Predicted)
Density 1.345±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 7.79±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

Methyl 3-benzenesulfonaMidobenzoate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Synthonix M57624 Methyl 3-benzenesulfonamidobenzoate 95+% 107922-46-3 100mg $80 2026-05-06 Buy
Synthonix M57624 Methyl 3-benzenesulfonamidobenzoate 95+% 107922-46-3 250mg $110 2026-05-06 Buy
Synthonix M57624 Methyl 3-benzenesulfonamidobenzoate 95+% 107922-46-3 1g $180 2026-05-06 Buy
Synthonix M57624 Methyl 3-benzenesulfonamidobenzoate 95+% 107922-46-3 5g $400 2026-05-06 Buy
Synthonix M57624 Methyl 3-benzenesulfonamidobenzoate 95+% 107922-46-3 10g $800 2026-05-06 Buy
Product number Packaging Price Buy
M57624 100mg $80 Buy
M57624 250mg $110 Buy
M57624 1g $180 Buy
M57624 5g $400 Buy
M57624 10g $800 Buy

Methyl 3-benzenesulfonaMidobenzoate Chemical Properties, Uses, Production

Synthesis

METHYL 3-AMINOBENZOATE

4518-10-9

Benzenesulfonyl chloride

98-09-9

Methyl 3-benzenesulfonaMidobenzoate

107922-46-3

Methyl 3-aminobenzoate (10 g, 66.2 mmol) was dissolved in pyridine (100 mL) and cooled in an ice bath for 15 minutes. Benzenesulfonyl chloride (8.53 mL, 66.2 mmol) was added slowly dropwise over 5 min using a syringe, followed by stirring the reaction mixture and gradually warming it to room temperature, the reaction lasted for 16 hours. The reaction mixture was slowly poured into a 1 M HCl solution (250 mL total volume) containing ice and the pH was adjusted to 2-3 to form a heterogeneous acidic mixture. The precipitate was collected by filtration and washed with plenty of water. The resulting solid was dried under high vacuum for 12 h to give the target product methyl 3-benzenesulfonylaminobenzoate (19.3 g, 100% yield) as an off-white solid.

References

[1] Patent: WO2010/126922, 2010, A1. Location in patent: Page/Page column 26
[2] Journal of Medicinal Chemistry, 2009, vol. 52, # 10, p. 3317 - 3327
[3] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 15, p. 4436 - 4440

4518-10-9
98-09-9
107922-46-3
Synthesis of Methyl 3-benzenesulfonaMidobenzoate from Methyl 3-aminobenzoate and Benzenesulfonyl chloride

Methyl 3-benzenesulfonaMidobenzoate Preparation Products And Raw materials

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Methyl 3-benzenesulfonaMidobenzoate methyl 3-(phenylsulfonamido)benzoate Benzoic acid, 3-[(phenylsulfonyl)amino]-, methyl ester 3-(phenylsulfonylacylamino)methyl benzoate 107922-46-3