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Z-VDVAD-AFC

Z-VDVAD-AFC structure

CAS No.: 219138-08-6

Chemical Name:: Z-VDVAD-AFC

Synonyms: Z-VDVAD-AFC;CBZ-VDVAD-AFC;Z-VDVAD-AFC USP/EP/BP;Z-Val-Asp-Ala-Asp-AFC;Z-VAL-ASP-VAL-ALA-ASP-AFC;CASPASE-2 SUBSTRATE I, FLUOROGENIC;L-α-Asparagine,N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-;L-α-Asparagine, N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI);N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine;(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxo-4-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]butanoic acid

CBNumber:: CB8269964

Molecular Formula:: C39H45F3N6O13

Molecular Weight:: 862.8

MDL Number:: MFCD01318834

MOL File:: 219138-08-6.mol

MSDS File:: SDS

Last updated:2025-06-18 16:39:26

Product description	Number	Pack Size	Price
CASPASE-2 SUBSTRATE I, FLUOROGENIC 95.00%	HCH0136645	5MG	$499.66
Z-Val-Asp-Val-Ala-Asp-AFC	32763	5MG	$805

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Z-VDVAD-AFC Properties

Boiling point	1153.6±65.0 °C(Predicted)
Density	1.399±0.06 g/cm3(Predicted)
storage temp.	-15°C
pka	4.09±0.10(Predicted)
Sequence	{Z}-Val-Asp-Val-Ala-Asp-{AFC}

Z-VDVAD-AFC price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	HCH0136645	CASPASE-2 SUBSTRATE I, FLUOROGENIC 95.00%	219138-08-6	5MG	$499.66	2021-12-16	Buy
Chem-Impex	32763	Z-Val-Asp-Val-Ala-Asp-AFC	219138-08-6	5MG	$805	2021-12-16	Buy

Product number	Packaging	Price	Buy
HCH0136645	5MG	$499.66	Buy
32763	5MG	$805	Buy

Z-VDVAD-AFC Chemical Properties,Uses,Production

Uses

Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].

References

[1] Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79. DOI:10.1016/j.freeradbiomed.2010.11.022

Z-VDVAD-AFC Preparation Products And Raw materials

Raw materials

Preparation Products

Z-VDVAD-AFC Suppliers

Global( 40)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29799	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	8026	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
Nanjing TGpeptide	+86-13347807150	support@tgpeptide.com	China	3279	58
Changsha MOL Changes Biotechnology Co., Ltd.	+8619375158599	info@molchanges.com	China	5218	58
LEON (NANJING) BIOTECHNOLOGY CO., LTD.	+8615051830413	sales@njleonbiotech.com	China	5482	58
DONBOO AMINO ACID COMPANY	+8618051385538	donboo@donboo.com	China	9363	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42934	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15402	60

Supplier	Advantage
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Chengdu Youngshe Chemical Co., Ltd.	58
Nanjing TGpeptide	58
Changsha MOL Changes Biotechnology Co., Ltd.	58
LEON (NANJING) BIOTECHNOLOGY CO., LTD.	58
DONBOO AMINO ACID COMPANY	58
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60

View Lastest Price from Z-VDVAD-AFC manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-06-25	Z-VDVAD-AFC 219138-08-6	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
	2020-01-09	Z-VDVAD-AFC 219138-08-6	US $1.00 / g	1g	≥98%	g/kg/Ton	Career Henan Chemical Co

Z-VDVAD-AFC
219138-08-6
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

Z-VDVAD-AFC
219138-08-6
US $1.00 / g
≥98%
Career Henan Chemical Co

219138-08-6(Z-VDVAD-AFC)Related Search:

Z-VAL-PHE-OME Z-VAL-VAL-ARG-AMC Z-VAL-ALA-ASN-AMC Z-YVAD-AFC Z-VEID-AFC

Z-TYR-SER-OH UROKINASE SUBSTRATE I, COLORIMETRIC Z-VAL-ALA-ASP-AMC BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE Z-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE

Z-VAL-LYS-LYS-ARG-AFC Z-VRPR-FMK (trifluoroacetate salt) L-Alaninamide,N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-[(2,6-dichlorobenzoyl)oxy]-1-(2-ethoxy-2-oxoethyl)-2-oxopropyl]-(9CI) AC-VDVAD-AFC SUC-ALA-ALA-ALA-AMC

Z-VDVAD-AFC AFC Caspase 2, Fluorometric Substrate, VDVAD-AFC

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CASPASE-2 SUBSTRATE I, FLUOROGENIC Z-VDVAD-AFC Z-VAL-ASP-VAL-ALA-ASP-AFC Z-Val-Asp-Ala-Asp-AFC (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxo-4-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]butanoic acid N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine L-α-Asparagine,N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- Z-VDVAD-AFC USP/EP/BP CBZ-VDVAD-AFC L-α-Asparagine, N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI) 219138-08-6 C39H45F3N6O13