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1,2-Difluorobenzene

1,2-Difluorobenzene structure

CAS No.: 367-11-3

Chemical Name:: 1,2-Difluorobenzene

Synonyms: difluorobenzene;O-DIFLUOROBENZENE;1,2-DifL;NSC 10275;2-Difluorobenzene;1,2-Difluorbenzol;o-difluoro-benzen;1，2-Dfluorobenzene;1,2-DIFLUOROBENZENE;1,2-difluroethylene

CBNumber:: CB8286000

Molecular Formula:: C6H4F2

Molecular Weight:: 114.09

MDL Number:: MFCD00000284

MOL File:: 367-11-3.mol

MSDS File:: SDS

Last updated:2026-01-13 11:26:05

Product description	Number	Pack Size	Price
1,2-Difluorobenzene 98%	126152	10g	$73.8
1,2-Difluorobenzene 98%	126152	50g	$213
1,2-Difluorobenzene >98.0%(GC)	D1627	5g	$29
1,2-Difluorobenzene >98.0%(GC)	D1627	25g	$81
1,2-Difluorobenzene	009521	5g	$418
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1,2-Difluorobenzene Properties

Melting point	−34 °C(lit.)
Boiling point	92 °C(lit.)
Density	1.158 g/mL at 25 °C(lit.)
refractive index	n20/D 1.443(lit.)
Flash point	36 °F
storage temp.	Flammables area
solubility	Chloroform, Methanol
form	Liquid
color	Clear colorless
Specific Gravity	1.158
Water Solubility	Not miscible or difficult to mix in water.
BRN	1905113
Dielectric constant	14.26
Stability	Stable. Incompatible with strong oxidizing agents. Highly flammable. Note low flash point.
InChI	1S/C6H4F2/c7-5-3-1-2-4-6(5)8/h1-4H
InChIKey	GOYDNIKZWGIXJT-UHFFFAOYSA-N
SMILES	Fc1ccccc1F
CAS DataBase Reference	367-11-3(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	AW7QGMW29C
NIST Chemistry Reference	Benzene, 1,2-difluoro-(367-11-3)
EPA Substance Registry System	Benzene, 1,2-difluoro- (367-11-3)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02

Signal word

Danger

Hazard statements

H225

Precautionary statements

P210

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

F,Xn

Risk Statements

11-20-2017/11/20

Safety Statements

7-16-29-33-7/9

RIDADR

UN 1993 3/PG 2

WGK Germany

RTECS

CZ5655000

Hazard Note

Flammable

HazardClass

PackingGroup

HS Code

29036990

Storage Class

3 - Flammable liquids

Hazard Classifications

Flam. Liq. 2

Limited Quantities

1.0 L (0.3 gallon) (liquid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	3
1		0

1,2-Difluorobenzene price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	126152	1,2-Difluorobenzene 98%	367-11-3	10g	$73.8	2025-07-31	Buy
Sigma-Aldrich	126152	1,2-Difluorobenzene 98%	367-11-3	50g	$213	2025-07-31	Buy
TCI Chemical	D1627	1,2-Difluorobenzene >98.0%(GC)	367-11-3	5g	$29	2025-07-31	Buy
TCI Chemical	D1627	1,2-Difluorobenzene >98.0%(GC)	367-11-3	25g	$81	2025-07-31	Buy
Usbiological	009521	1,2-Difluorobenzene	367-11-3	5g	$418	2021-12-16	Buy

Product number	Packaging	Price	Buy
126152	10g	$73.8	Buy
126152	50g	$213	Buy
D1627	5g	$29	Buy
D1627	25g	$81	Buy
009521	5g	$418	Buy

1,2-Difluorobenzene Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Uses

1,2-Difluorobenzene is used in electrochemical analysis of transition metal complexes. 1,2-difluorobenzene is also a potent inhibitor of NMDA receptor.

Uses

1,2-Difluorobenzene(1,2-DFB) has been used to study the mechanism of dissociation of o-, m- and p-difluorobenzene ions by threshold photoelectron photoion coincidence spectroscopy. It has been used to study the room temperature adsorption of 1,2-DFB, 1,2-dichlorobenzene and 1,2-dibromobenzene on Si(100)2x1 by X-ray photoelectron spectroscopy and temperature programmed desorption. It is used as solvent in electrochemical studies on transition metal complexes. It is also applied as a solvent useful for electrochemical studies on transition metal complexes.

Definition

ChEBI: A difluorobenzene carrying fluoro groups at positions 1 and 2.

General Description

1,2-Difluorobenzene undergoes defluorination under very mild conditions by H₂ in the presence of NaOAc over rhodium pyridylphosphine and bipyridyl complexes tethered on a silica-supported palladium catalyst.

1,2-Difluorobenzene Preparation Products And Raw materials

Raw materials

Fluoroboric acid Hydrochloric acid

Preparation Products

2,3-Difluorophenylboronic acid Benzeneacetonitrile, 2-fluoro-alpha,alpha-dimethyl- 2-Chloro-1-(3,4-difluoro-phenyl)-ethanone 2,3-Difluorobenzaldehyde 2,3-Difluorophenol

CHEMBRDG-BB 4003866 (S)-2-(3,4-Difluorophenyl)oxirane 1,2-difluoro-4,5-dinitrobenzene (1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide 4,7-Bis(5-broMothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5] thiadiazole

(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid 2-Bromo-4,5-difluorobenzonitrile 3,4-Difluorobenzyl chloride METHYL 3,4-DIFLUOROBENZOATE

1,4-DIBROMO-2,3-DIFLUOROBENZENE

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1,2-Difluorobenzene Suppliers

Global( 362)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20128	58
Springchem New Material Technology Co.,Limited	+86-021-62885108 +8613917661608	info@spring-chem.com	China	2068	57
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21597	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Springchem New Material Technology Co.,Limited	57
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58

View Lastest Price from 1,2-Difluorobenzene manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-01-28	o-Difluoro Benzene 367-11-3	US $0.00 / kg	20kg	99%	20 tons	Qingdao RENAS Polymer Material Co., Ltd.
2025-09-25	1,2-Difluorobenzene 367-11-3	US $100.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2022-02-19	3-chloro-2-fluoroanisole 367-11-3	US $0.00 / KG	1KG	98.4%	100 tons	Honest Joy Holdings Limited

o-Difluoro Benzene
367-11-3
US $0.00 / kg
99%
Qingdao RENAS Polymer Material Co., Ltd.

1,2-Difluorobenzene
367-11-3
US $100.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

3-chloro-2-fluoroanisole
367-11-3
US $0.00 / KG
98.4%
Honest Joy Holdings Limited

1,2-Difluorobenzene Spectrum

1,2-Difluorobenzene(367-11-3)MS 1,2-Difluorobenzene(367-11-3)¹HNMR 1,2-Difluorobenzene(367-11-3)¹³CNMR 1,2-Difluorobenzene(367-11-3)IR1 1,2-Difluorobenzene(367-11-3)Raman

367-11-3(1,2-Difluorobenzene)Related Search:

4-Fluorobenzaldehyde Florfenicol Transfluthrin Ticagrelor Sulfone 2-(((3aR,4S,6R,6aS)-6-(7-aMino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2-diMethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol

(3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)aMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2- Ticagrelor Related Compound 3 TRANSAMINE 1,2-Cyclopentanediol, 3-[7-aMino-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyriMidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)- 4-Chloro-2-propylsulfanyl-pyrimidine

Ticagrelor Related Compound 44 (trans)-2-(3,4-difluorophenyl)cyclopropanecarboxamide 4,6-dichloro-2-(propylthio)pyriMidine Ticagrelor diastereoMer Ticagrelor Impurity N

Cyclopropanamine, 2-(3-fluorophenyl)-, (1R,2S)- (9CI) ethyCyclopropanamine, 2-(3,4-difluorophenyl)-, (1R,2S)- (REACH) Triethyl phosphonoacetate

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Adjacent two fluorine benzene O-DIFLUOROBENZENE 2-Difluorobenzene 1,2-Difluorobenzene,98+% o-Difluorobenzene,99% 1,2-Difluorobenzene 98% 1，2-Dfluorobenzene 1,2-Bifluorobenzene ,98% 1,2-Difluorobenzene, 98% 10ML NSC 10275 Ticagrelor Impurity 147 1,2-DIFLUOROBENZENE 1,2-Difluorbenzol 1,2-difluroethylene Benzene, o-difluoro- benzene,1,2-difluoro- Benzene,o-difluoro- difluorobenzene o-difluoro-benzen ortho-Difluorobenzene 1,2-Difluorobenzene > 1,2-DifL 1,2-Difluorobenzene1,2 1,2-Difluorobenzene ISO 9001：2015 REACH 1,2-Difluorobenzene, ≥ 98.0% 367-11-3 C6H4F2 367113 Halogenated Hydrocarbons Organic Building Blocks Building Blocks Aryl C6 Aromatic Hydrocarbons (substituted) & Derivatives Fluorobenzene Aryl Halogenated Hydrocarbons Aryl Fluorinated Building Blocks Building Blocks Chemical Synthesis Fluorinated Building Blocks Halogenated Hydrocarbons Organic Building Blocks Organic Fluorinated Building Blocks Isoquinolines ,Quinaldines ,Quinolines ,Quinazolines ,Indolines Other Fluorinated Organic Building Blocks Fluorine series alkyl Fluorine K00001 C6