2-Chloro-5-nitronicotinic acid
- CAS No.
- 42959-38-6
- Chemical Name:
- 2-Chloro-5-nitronicotinic acid
- Synonyms
- 2-Chloro-5-nitronicotinicaci;2-Chloro-5-nitronicoinic acid;2-CHLORO-5-NITRONICOTINIC ACID;2-Chloro-5-nitropyridin-3-carboxylic acid;2-CHLORO-5-NITROPYRIDINE-3-CARBOXYLIC ACID;2-Chloro-5-nitro-3-pyridinecarboxylic acid;3-Pyridinecarboxylic acid, 2-chloro-5-nitro-;2-Chloro-5-nitropyridine-3-carboxylic acid, 3-Carboxy-2-chloro-5-nitropyridine
- CBNumber:
- CB8291477
- Molecular Formula:
- C6H3ClN2O4
- Molecular Weight:
- 202.55
- MDL Number:
- MFCD06658402
- MOL File:
- 42959-38-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-5-nitronicotinicacid | C381113 | 500mg | $65 |
| 2-Chloro-5-nitronicotinic acid 95+% | 055440 | 25g | $84 |
| 2-Chloro-5-nitronicotinic acid 95% | 4H54-5-X1 | 250mg | $24 |
| 2-Chloro-5-nitronicotinic acid 95+% | 055440 | 5g | $24 |
| 2-Chloro-5-nitronicotinic acid 95+% | 055440 | 100g | $236 |
| More product size | |||
| Melting point | 140-143℃ |
|---|---|
| Boiling point | 384.8±42.0 °C(Predicted) |
| Density | 1.702±0.06 g/cm3(Predicted) |
| storage temp. | Store at room temperature |
| form | Solid |
| pka | 1.57±0.10(Predicted) |
| color | White to yellow |
| Sensitive | Moisture Sensitive |
| InChI | InChI=1S/C6H3ClN2O4/c7-5-4(6(10)11)1-3(2-8-5)9(12)13/h1-2H,(H,10,11) |
| InChIKey | WOFZRBCITDVRON-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=C([N+]([O-])=O)C=C1C(O)=O |
| CAS DataBase Reference | 42959-38-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2-Chloro-5-nitronicotinic acid price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C381113 | 2-Chloro-5-nitronicotinicacid | 42959-38-6 | 500mg | $65 | 2021-12-16 | Buy |
| Matrix Scientific | 055440 | 2-Chloro-5-nitronicotinic acid 95+% | 42959-38-6 | 25g | $84 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H54-5-X1 | 2-Chloro-5-nitronicotinic acid 95% | 42959-38-6 | 250mg | $24 | 2021-12-16 | Buy |
| Matrix Scientific | 055440 | 2-Chloro-5-nitronicotinic acid 95+% | 42959-38-6 | 5g | $24 | 2021-12-16 | Buy |
| Matrix Scientific | 055440 | 2-Chloro-5-nitronicotinic acid 95+% | 42959-38-6 | 100g | $236 | 2021-12-16 | Buy |
2-Chloro-5-nitronicotinic acid Chemical Properties,Uses,Production
Application
2-Chloro-5-nitronicotinic acid is a chemical intermediate used in the synthesis of pesticides and pharmaceuticals. For example, Rhône-Poulenc Agribusiness in France uses it to synthesize novel herbicides.
Synthesis
2-Hydroxy-5-nitro-nicotinic acid (2.7 mmol) in a mixture of NJV- dimethylformamide (2.7 mmol) and thionyl chloride (5 ml) was heated at 80 0C for 1 h. The mixture was allowed to cool and concentrated in a vacuum. To the resulting residue, ice water (20 ml) was added, and with vigorous stirring, a precipitate formed. The precipitate was filtered off and dried in a vacuum oven to give a white solid 2-Chloro-5-nitronicotinic acid (68 percent).
References
[1] Journal of Medicinal Chemistry, 1992, vol. 35, # 10, p. 1887 - 1897
[2] Beilstein Journal of Organic Chemistry, 2009, vol. 5,
[3] Patent: EP904262, 2004, B1. Location in patent: Page 244
[4] Patent: WO2008/46135, 2008, A1. Location in patent: Page/Page column 42-43
[5] Bioorganic and Medicinal Chemistry Letters, 2000, vol. 10, # 11, p. 1151 - 1154
2-Chloro-5-nitronicotinic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +8613651600618 | sales@worldyachem.com | China | 967 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| QINGDAO KAIENSI INTERNATIONAL TRADE CO.,LTD. | +86-0532-8699-9256 +8615254267723 | kaley@cnfdevelop.com | China | 1410 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
View Lastest Price from 2-Chloro-5-nitronicotinic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | 2-Chloro-5-nitronicotinic acid
42959-38-6
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
![]() |
2019-07-12 | 2-Chloro-5-nitronicotinic acid
42959-38-6
|
US $1.00 / KG | 1KG | 99% | 1ton | Career Henan Chemical Co | |
![]() |
2019-07-06 | 2-Chloro-5-nitronicotinic acid
42959-38-6
|
US $2.00 / kg | 1kg | 99% | 100kg | Career Henan Chemical Co |
-

- 2-Chloro-5-nitronicotinic acid
42959-38-6
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-

- 2-Chloro-5-nitronicotinic acid
42959-38-6
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
-

- 2-Chloro-5-nitronicotinic acid
42959-38-6
- US $2.00 / kg
- 99%
- Career Henan Chemical Co





