2-Amino-3-methyl-5-nitropyridine
- CAS No.
- 18344-51-9
- Chemical Name:
- 2-Amino-3-methyl-5-nitropyridine
- Synonyms
- 3-METHYL-5-NITROPYRIDIN-2-AMINE;2-Bromo-5-Nitro-3;TIMTEC-BB SBB005535;2-AMINO-5-NITRO-3-PICOLINE;2-Amino-5-nitro-3-picoline,98%;3-Methyl-5-nitro-2-pyridinamine;2-AMINO-3-METHYL-5-NITROPYRIDINE;2-Amino-5-nitro-3-methylpyridine;3-Methyl-5-nitropyridine-2-amine;2-Pyridinamine,3-methyl-5-nitro-
- CBNumber:
- CB8294382
- Molecular Formula:
- C6H7N3O2
- Molecular Weight:
- 153.14
- MDL Number:
- MFCD03095060
- MOL File:
- 18344-51-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Amino-3-methyl-5-nitropyridine 97% | 703974 | 1g | $56 |
| 2-Amino-3-methyl-5-nitropyridine 97% | 703974 | 5g | $57.7 |
| 2-Amino-3-methyl-5-nitropyridine >98.0%(GC)(T) | A1891 | 1g | $25 |
| 2-Amino-3-methyl-5-nitropyridine >98.0%(GC)(T) | A1891 | 5g | $75 |
| 2-Amino-3-methyl-5-nitropyridine | A1378-92 | 1g | $425 |
| More product size | |||
| Melting point | 256-260 °C |
|---|---|
| Boiling point | 276.04°C (rough estimate) |
| Density | 1.3682 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 3.13±0.49(Predicted) |
| form | powder to crystal |
| color | Light yellow to Yellow to Orange |
| BRN | 126947 |
| InChI | InChI=1S/C6H7N3O2/c1-4-2-5(9(10)11)3-8-6(4)7/h2-3H,1H3,(H2,7,8) |
| InChIKey | JLPYUDJJBGYXEZ-UHFFFAOYSA-N |
| SMILES | C1(N)=NC=C([N+]([O-])=O)C=C1C |
| CAS DataBase Reference | 18344-51-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P305+P351+P338+P310 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37/38-20/21/22-41-22 | |||||||||
| Safety Statements | 36/37/39-26-22-39-36-37 | |||||||||
| RIDADR | UN2811 | |||||||||
| WGK Germany | 1 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
2-Amino-3-methyl-5-nitropyridine price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 703974 | 2-Amino-3-methyl-5-nitropyridine 97% | 18344-51-9 | 1g | $56 | 2023-06-20 | Buy |
| Sigma-Aldrich | 703974 | 2-Amino-3-methyl-5-nitropyridine 97% | 18344-51-9 | 5g | $57.7 | 2023-01-07 | Buy |
| TCI Chemical | A1891 | 2-Amino-3-methyl-5-nitropyridine >98.0%(GC)(T) | 18344-51-9 | 1g | $25 | 2025-07-31 | Buy |
| TCI Chemical | A1891 | 2-Amino-3-methyl-5-nitropyridine >98.0%(GC)(T) | 18344-51-9 | 5g | $75 | 2025-07-31 | Buy |
| Usbiological | A1378-92 | 2-Amino-3-methyl-5-nitropyridine | 18344-51-9 | 1g | $425 | 2021-12-16 | Buy |
2-Amino-3-methyl-5-nitropyridine Chemical Properties,Uses,Production
Chemical Properties
White to yellow crystalline powder.
Synthesis
1603-40-3
18344-51-9
The general procedure for the synthesis of 2-amino-3-methyl-5-nitropyridine from 2-amino-3-methylpyridine was as follows: 3-methylpyridin-2-amine (5.0 g, 46.2 mmol) was dissolved in concentrated sulfuric acid (24 mL) and the mixture was cooled to 0 °C. At the same time, fuming nitric acid (density = 1.5, 3.5 mL) was cooled to 0 °C. Concentrated sulfuric acid (3.5 mL) was slowly added dropwise to the reaction mixture while keeping the temperature below 20°C. Subsequently, the stirred mixture was gradually warmed to 20 °C and transferred to a second flask in 3-5 mL batches. The second flask was heated to 35-40°C (note: the temperature should not exceed 40°C and the temperature should be carefully monitored after each addition of a new batch). Next, the reaction mixture was continued to be stirred at 50°C for 30 minutes. Once the reaction is complete, the mixture is cooled to room temperature and neutralized with concentrated ammonia. At this point, a precipitate is generated, which is filtered and washed sequentially with water and 50% aqueous DMFA (6 mL). Finally, the product was purified by recrystallization from DMFA to give 3-methyl-5-nitropyridin-2-amine (2.52 g, 35% yield).
References
[1] Patent: EP1894924, 2008, A1. Location in patent: Page/Page column 36
[2] Journal of Organic Chemistry, 1949, vol. 14, p. 328,331
[3] Journal of the American Chemical Society, 1955, vol. 77, p. 3154
2-Amino-3-methyl-5-nitropyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20175 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +852-6619 3215 +86-17731935328 | sales03@chemcn.cn | China | 970 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| BTC Nantong Pharmaceuticals Technology Co.,Ltd | +8618068193575 | sales4@btcpharm.com | China | 251 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
View Lastest Price from 2-Amino-3-methyl-5-nitropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-09-25 | 2-Amino-3-methyl-5-nitropyridine
18344-51-9
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2025-07-25 | 2-Amino-3-methyl-5-nitropyridine
18344-51-9
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-04-04 | 2-Amino-3-methyl-5-nitropyridine
18344-51-9
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 2-Amino-3-methyl-5-nitropyridine
18344-51-9
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 2-Amino-3-methyl-5-nitropyridine
18344-51-9
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-Amino-3-methyl-5-nitropyridine
18344-51-9
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
