6-Amino-1H-indazole-7-carboxylic acid
- CAS No.
- 73907-95-6
- Chemical Name:
- 6-Amino-1H-indazole-7-carboxylic acid
- Synonyms
- TIMTEC-BB SBB002550;7-Carboxy-1H-indazole-6-amine;6-Amino-7-carboxy-1H-indazole;6-Amino-1H-indazole-7-carboxylic acid;1H-Indazole-7-carboxylic acid, 6-aMino-
- CBNumber:
- CB8296412
- Molecular Formula:
- C8H7N3O2
- Molecular Weight:
- 177.16
- MDL Number:
- MFCD03856017
- MOL File:
- Mol file
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332 |
| Precautionary statements | P260-P280 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22 |
| HS Code | 2933998090 |
6-Amino-1H-indazole-7-carboxylic acid price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR13445 | 6-Amino-1H-indazole-7-carboxylic acid 98% | 73907-95-6 | 100mg | $107 | 2026-06-04 | Buy |
| Apolloscientific | OR13445 | 6-Amino-1H-indazole-7-carboxylic acid 98% | 73907-95-6 | 250mg | $165 | 2026-06-04 | Buy |
| Apolloscientific | OR13445 | 6-Amino-1H-indazole-7-carboxylic acid 98% | 73907-95-6 | 1g | $463 | 2026-06-04 | Buy |
| Matrix Scientific | 119641 | 6-Amino-1H-indazole-7-carboxylic acid | 73907-95-6 | 100.00mg | $57 | 2026-05-18 | Buy |
| Matrix Scientific | 119641 | 6-Amino-1H-indazole-7-carboxylic acid | 73907-95-6 | 250.00mg | $90 | 2026-05-18 | Buy |
6-Amino-1H-indazole-7-carboxylic acid Chemical Properties, Uses, Production
Synthesis
![pyrrolo[2,3-g]indazole-7,8(1H,6H)-dione](/CAS/GIF/73907-94-5.gif)
73907-94-5
73907-95-6
Pyrrolo[2,3-g]indazole-7,8(1H,6H)-dione (Formula 7, the product of Example II, 9.4 g, 50 mmol) was used as a raw material, which was dissolved in 10% aqueous sodium hydroxide solution (100 mL). Subsequently, 10% aqueous hydrogen peroxide solution (17 mL, 50 mmol) was slowly added at 100 °C. The reaction mixture was kept at 100°C for 10 minutes until the release of carbon dioxide gas stopped. Next, the pH of the reaction solution was adjusted with concentrated hydrochloric acid to 4.0-5.5. The resulting 6-amino-1H-indazole-7-carboxylic acid (formula 8) was collected by filtration and washed with cold water, and finally dried under vacuum in the presence of CaCl2 to give 7.71 g of the product in brown powder form in 87% yield with a melting point of 205 °C (decomposition started at 177 °C). The infrared spectrum (KBr) of the product showed characteristic absorption peaks: 1580, 1630, 1660 cm-1 (corresponding to aromatic ring and carbonyl carboxylic acid, respectively). The NMR hydrogen spectrum (100 MHz, DMSO-d6) data were as follows: δ 6.70 (d, 1H, J=9Hz, H-4), ca. 6.80-9.00 (D2O-exchangeable broad peak, 2H, NH2), 7.66 (d, 1H, J=9Hz, H-5), and 7.93 (s, 1H, H-3). The mass spectrum (70 eV) showed molecular ion peaks m/e 177 (100%, M+) and m/e 159 (86%, M+-H2O). Samples recrystallized from methanol failed to yield satisfactory data by elemental analysis.
References
[1] Tetrahedron Letters, 1980, vol. 21, # 32, p. 3029 - 3032
[2] Journal of Organic Chemistry, 1980, vol. 45, # 15, p. 3072 - 3077
[3] Heterocycles, 1981, vol. 15, # 2, p. 1053 - 1059
[4] Patent: US4223143, 1980, A
[5] Patent: WO2007/93402, 2007, A1. Location in patent: Page/Page column 42
6-Amino-1H-indazole-7-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1399 | 59 |
| Jinan Trio PharmaTech Co., Ltd. | 0531-88811783 | sales@trio-pharmatech.com | China | 1856 | 62 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Jinan HM Medical Technology Co., Ltd. | 0531-88262980 13156180564 | jnhengmao@163.com | China | 100 | 62 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
View Latest Price from 6-Amino-1H-indazole-7-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID
73907-95-6
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-09-11 | 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID
73907-95-6
|
$1.00 | 1KG | 99%Min | 10 tons | Career Henan Chemical Co |
-
- 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID
73907-95-6
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 6-AMINO-1H-INDAZOLE-7-CARBOXYLIC ACID
73907-95-6
- $1.00
- 99%Min
- Career Henan Chemical Co
