Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Bromo-4-hydroxybenzoicacid

2-Bromo-4-hydroxybenzoicacid

2-Bromo-4-hydroxybenzoicacid Structure
2-Bromo-4-hydroxybenzoicacid structure
CAS No.
28547-28-6
Chemical Name:
2-Bromo-4-hydroxybenzoicacid
Synonyms
2-Bromo-4-hydroxybenzoicacid;Benzoic acid, 2-bromo-4-hydroxy-
CBNumber:
CB83044339
Molecular Formula:
C7H5BrO3
Molecular Weight:
217.02
MDL Number:
MFCD16999959
MOL File:
28547-28-6.mol
MSDS File:
SDS
Last updated:2026-05-28 04:14:03
Request For Quotation

2-Bromo-4-hydroxybenzoicacid Properties

Melting point 151 °C
Boiling point 366.3±32.0 °C(Predicted)
Density 1.861±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form powder
pka 3.22±0.10(Predicted)
color Off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2918999090

2-Bromo-4-hydroxybenzoicacid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR400738 2-Bromo-4-hydroxybenzoic acid 95% 28547-28-6 250mg $21 2026-06-04 Buy
Apolloscientific OR400738 2-Bromo-4-hydroxybenzoic acid 95% 28547-28-6 1g $47 2026-06-04 Buy
Apolloscientific OR400738 2-Bromo-4-hydroxybenzoic acid 95% 28547-28-6 5g $204 2026-06-04 Buy
Activate Scientific AS116242 2-Bromo-4-hydroxybenzoic acid 95% 28547-28-6 1g $89 2026-06-04 Buy
Activate Scientific AS116242 2-Bromo-4-hydroxybenzoic acid 95% 28547-28-6 5g $233 2026-06-04 Buy
Product number Packaging Price Buy
OR400738 250mg $21 Buy
OR400738 1g $47 Buy
OR400738 5g $204 Buy
AS116242 1g $89 Buy
AS116242 5g $233 Buy

2-Bromo-4-hydroxybenzoicacid Chemical Properties, Uses, Production

Uses

2-Bromo-4-hydroxybenzoic acid is a bromo derivative of hydroxybenzoic acid, a useful building block. 2-Bromo-4-hydroxybenzoic acid has been used in the preparation of urolithins which interfere with the CYP1B1 protein which is linked with prostate cancer.

Synthesis

Benzaldehyde, 2-broMo-4-hydroxy

22532-60-1

2-Bromo-4-hydroxybenzoicacid

28547-28-6

2-Bromo-4-hydroxybenzaldehyde (1.7 g, 8.46 mmol, 1.0 equiv) was used as starting material and dissolved in 30 mL of 2 M aqueous sodium hydroxide solution. Potassium permanganate (2.7 g, 16.92 mmol, 2.0 equiv) was added in batches under ice bath cooling conditions. The reaction mixture was then slowly warmed to room temperature with continuous stirring for 2 hours. After completion of the reaction, the insoluble impurities were removed by filtration and the filtrate was washed once with dichloromethane. To the filtrate, 2 M aqueous hydrochloric acid was slowly added and the pH was adjusted to 1. The aqueous phase was extracted with ethyl acetate, the organic phases were combined and dried over anhydrous sodium sulfate. The organic phase was concentrated under reduced pressure to give the white solid product 2-bromo-4-hydroxybenzoic acid (1.6 g, 88% yield).

References

[1] Patent: CN107383024, 2017, A. Location in patent: Paragraph 0481

2-Bromo-4-hydroxybenzoicacid Preparation Products And Raw materials

Raw materials

Benzaldehyde, 2-broMo-4-hydroxy Sodium hydroxide Potassium permanganate

Preparation Products

Methyl2-bromo-4-hydroxybenzoate 4-Benzyl 1-Methyl 2-nitroterephthalate

2-Bromo-4-hydroxybenzoicacid Suppliers

Global Suppliers ( 48)
Supplier Tel Email Country ProdList Advantage
Beijing Eternalchem Co,. Ltd. 010-59484199 18611897322;18611897322; sales@eternalchem.com China 1993 60
Changzhou Wanyao Biotechnology Co., Ltd. 0519-89185693 15312551983 2410037592@qq.com China 278 55
SuZhou ShiYa Biopharmaceuticals, Inc. 0512-0512-52358471 17715136450 sales@shiyabiopharm.com China 9814 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Zhengzhou Huiju Chemical Co., Ltd. 0371-55900031 18137872243 3927209986@qq.com China 9998 55
3A Chemicals 400-668-9898 service@3achem.com China 20535 58
Win-Win Chemical CO., Limited 0577-64498589 15325081899 sales@win-winchemical.com China 1086 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Cool Pharm, Ltd 021-58581007 18019463053 sales@coolpharm.com China 9999 58
Supplier Advantage
Beijing Eternalchem Co,. Ltd. 60
Changzhou Wanyao Biotechnology Co., Ltd. 55
SuZhou ShiYa Biopharmaceuticals, Inc. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Zhengzhou Huiju Chemical Co., Ltd. 55
3A Chemicals 58
Win-Win Chemical CO., Limited 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Cool Pharm, Ltd 58

2-Bromo-4-hydroxybenzoicacid Spectrum

2-Bromo-4-hydroxybenzoicacid(28547-28-6)1HNMR

28547-28-6 (2-Bromo-4-hydroxybenzoicacid) Related Search:

Benzaldehyde, 2-broMo-4-hydroxy Methyl2-bromo-4-hydroxybenzoate 2-broMo-4-hydroxybenzonitrile 3-Bromo-4-hydroxymethyl-phenol 3-(2-Aminoethyl)pyridine
2-bromo-5-hydroxybenzoic acid

1of2

2-Bromo-4-hydroxybenzoicacid Benzoic acid, 2-bromo-4-hydroxy- 28547-28-6