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Propargyl-PEG4-acid

CAS No.
1415800-32-6
Chemical Name:
Propargyl-PEG4-acid
Synonyms
Alkyne-PEG4-COOH;Propargyl-PEG4-CH2CO2H;Propargyl-PEG4-PA;Propargyl-PEG4-acid;PROPARGYL-PEG4-COOH;Propargyl-PEG3-C2-COOH;Propyne-PEG3-CH2CH2COOH;Propargyl-PEG3-CH2CH2COOH;4,7,10,13-tetraoxahexadec-15-ynoic acid;4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid
CBNumber:
CB83048731
Molecular Formula:
C12H20O6
Molecular Weight:
260.28
MDL Number:
MFCD22683284
MOL File:
1415800-32-6.mol
MSDS File:
SDS
Last updated:2026-05-28 04:16:17
Product description Number Pack Size Price
Propargyl-PEG4-acid 902543 250MG $322
Propargyl-PEG4-acid 902543 1G $1070
Propargyl-PEG4-acid ≥97% CS-0108223 250mg $19
Propargyl-PEG4-acid ≥97% CS-0108223 1g $31
Propargyl-PEG4-acid ≥97% CS-0108223 5g $133
More product size

Propargyl-PEG4-acid Properties

Boiling point 388.0±37.0 °C(Predicted)
Density 1.129±0.06 g/cm3(Predicted)
refractive index n/D 1.460
storage temp. -20°C
solubility Soluble in Water, DMSO, DCM, DMF
pka 4.28±0.10(Predicted)
form Viscous Liquid
color Colorless to light yellow
Appearance colorless to yellow oil
InChIKey WMBXAUWIPBFEOK-UHFFFAOYSA-N
SMILES OC(CCOCCOCCOCCOCC#C)=O
UNSPSC Code 12352106
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Danger
Hazard statements  H242
Precautionary statements  P210-P234-P235-P240-P370+P378-P403
WGK Germany  WGK 3
Storage Class 5.2 - Organic peroxides and self-reacting hazardous materials
Hazard Classifications Self-react. C

Propargyl-PEG4-acid price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 902543 Propargyl-PEG4-acid 1415800-32-6 250MG $322 2026-04-30 Buy
Sigma-Aldrich 902543 Propargyl-PEG4-acid 1415800-32-6 1G $1070 2023-06-20 Buy
ChemScene CS-0108223 Propargyl-PEG4-acid ≥97% 1415800-32-6 250mg $19 2026-06-04 Buy
ChemScene CS-0108223 Propargyl-PEG4-acid ≥97% 1415800-32-6 1g $31 2026-06-04 Buy
ChemScene CS-0108223 Propargyl-PEG4-acid ≥97% 1415800-32-6 5g $133 2026-06-04 Buy
Product number Packaging Price Buy
902543 250MG $322 Buy
902543 1G $1070 Buy
CS-0108223 250mg $19 Buy
CS-0108223 1g $31 Buy
CS-0108223 5g $133 Buy

Propargyl-PEG4-acid Chemical Properties,Uses,Production

Description

Propargyl-PEG4-acid is a PEG reagent with an alkyne and a terminal carboxylic acid. The carboxylic acid reacts with primary amine groups with the help of activators (e.g. EDC, or HATU). The 4-unit PEG spacer increases hydrophilicity. The alkyne can participate in copper-catalyzed Click Chemistry.

Uses

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC molecules) for targeted protein degradation.

reaction suitability

reagent type: linker

IC 50

PEGs

Propargyl-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 92)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
LAURENT
+8618100176782 sun@laurentpeg.com China 365 58
9i LLC
+18039569191 MWan@NiNeiLab.com United States 418 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5742 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
Wuhan Borenpharm Co., Ltd
027-65563561 18717150066 3207347307@qq.com CHINA 1238 58
XIAMEN SINOPEG BIOTECH CO., LTD.
+86-0592-7761068 +8617350879715 changaiwei@sinopeg.com China 1125 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58

View Lastest Price from Propargyl-PEG4-acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Propargyl-PEG4-acid pictures 2026-05-11 Propargyl-PEG4-acid
1415800-32-6
10g TargetMol Chemicals Inc.
Propargyl-PEG4-PA pictures 2026-02-05 Propargyl-PEG4-PA
1415800-32-6
1g 98% 1g/bottle, 10g/bottle, 100g/bottle XIAMEN SINOPEG BIOTECH CO., LTD.
Propargyl-PEG3-CH2CH2COOH pictures 2026-01-29 Propargyl-PEG3-CH2CH2COOH
1415800-32-6
1g 98% 500kg LAURENT

Propargyl-PEG4-acid Spectrum

Propargyl-PEG4-acid Propyne-PEG3-CH2CH2COOH PROPARGYL-PEG4-COOH Propargyl-PEG3-CH2CH2COOH 4,7,10,13-tetraoxahexadec-15-ynoic acid 4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid Propargyl-PEG3-CH2CH2COOH/4,7,10,13-Tetraoxahexadec-15-ynoic acid Propargyl-PEG3-C2-COOH 3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoic acid Propargyl-PEG4-PA Alkyne-PEG4-COOH Propargyl-PEG4-CH2CO2H 1415800-32-6 5800-32-6 peg