Propargyl-PEG4-acid
- CAS No.
- 1415800-32-6
- Chemical Name:
- Propargyl-PEG4-acid
- Synonyms
- Alkyne-PEG4-COOH;PROPARGYL-PEG4-COOH;Propargyl-PEG4-acid;Propargyl-PEG3-C2-COOH;Propargyl-PEG4-CH2CO2H;Propyne-PEG3-CH2CH2COOH;Propargyl-PEG3-CH2CH2COOH;4,7,10,13-tetraoxahexadec-15-ynoic acid;4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid;3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoic acid
- CBNumber:
- CB83048731
- Molecular Formula:
- C12H20O6
- Molecular Weight:
- 260.28
- MDL Number:
- MFCD22683284
- MOL File:
- 1415800-32-6.mol
| Boiling point | 388.0±37.0 °C(Predicted) |
|---|---|
| Density | 1.129±0.06 g/cm3(Predicted) |
| refractive index | n/D 1.460 |
| storage temp. | -20°C |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 4.28±0.10(Predicted) |
| form | Viscous Liquid |
| color | Colorless to light yellow |
| Appearance | colorless to yellow oil |
| UNSPSC Code | 12352106 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|---|---|
| Signal word | Danger |
| Hazard statements | H242 |
| Precautionary statements | P210-P234-P235-P240-P370+P378-P403 |
Propargyl-PEG4-acid price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 902543 | Propargyl-PEG4-acid | 1415800-32-6 | 250MG | $302 | 2025-07-31 | Buy |
| Sigma-Aldrich | 902543 | Propargyl-PEG4-acid | 1415800-32-6 | 1G | $1070 | 2023-06-20 | Buy |
| TRC | P839603 | Propargyl-PEG4-acid | 1415800-32-6 | 100mg | $265 | 2021-12-16 | Buy |
| Activate Scientific | AS103922 | Propargyl-PEG3-CH2CH2COOH 95+% | 1415800-32-6 | 5G | $1286 | 2021-12-16 | Buy |
| BroadPharm | BP-21094 | Propargyl-PEG4-acid 98% | 1415800-32-6 | 250mg | $360 | 2021-12-16 | Buy |
Propargyl-PEG4-acid Chemical Properties,Uses,Production
Description
Propargyl-PEG4-acid is a PEG reagent with an alkyne and a terminal carboxylic acid. The carboxylic acid reacts with primary amine groups with the help of activators (e.g. EDC, or HATU). The 4-unit PEG spacer increases hydrophilicity. The alkyne can participate in copper-catalyzed Click Chemistry.
Uses
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
reaction suitability
reagent type: linker
IC 50
PEGs
Propargyl-PEG4-acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20185 | 58 |
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5744 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32432 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
View Lastest Price from Propargyl-PEG4-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-25 | Propargyl-PEG4-acid
1415800-32-6
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2025-06-07 | Propargyl-PEG4-acid
1415800-32-6
|
US $0.00 / g | 5g | >98.00% | 5g | Xian confluore Biological Technology Co., Ltd. | |
 |
2024-10-28 | Propargyl-PEG4-acid
1415800-32-6
|
US $0.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Propargyl-PEG4-acid
1415800-32-6
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-
- Propargyl-PEG4-acid
1415800-32-6
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
-
- Propargyl-PEG4-acid
1415800-32-6
- US $0.00 / mg
- TargetMol Chemicals Inc.
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