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Methylamino-PEG1-acid

CAS No.
1367918-21-5
Chemical Name:
Methylamino-PEG1-acid
Synonyms
Me-NH-PEG1-CH2CH2COOH;Methylamino-PEG1-acid;Methylamino-PEG1-acid HCl salt;Propanoic acid, 3-[2-(methylamino)ethoxy]-
CBNumber:
CB83062553
Molecular Formula:
C6H13NO3
Molecular Weight:
147.17
MDL Number:
MFCD26783686
MOL File:
1367918-21-5.mol
Last updated:2025-04-18 09:52:53

Methylamino-PEG1-acid Properties

Boiling point 253.9±20.0 °C(Predicted)
Density 1.071±0.06 g/cm3(Predicted)
pka 4.24±0.10(Predicted)

Methylamino-PEG1-acid price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific BIPG1535 Methylamino-PEG1-acid 98% 1367918-21-5 100mg $720 2026-06-04 Buy
Apolloscientific BIPG1535 Methylamino-PEG1-acid 98% 1367918-21-5 250mg $1097 2026-06-04 Buy
Apolloscientific BIPG1535 Methylamino-PEG1-acid 98% 1367918-21-5 1g $1831 2026-06-04 Buy
BroadPharm bp-22395 Methylamino-PEG1-acid HCl salt 98% 1367918-21-5 100MG $360 2026-05-24 Buy
BroadPharm bp-22395 Methylamino-PEG1-acid HCl salt 98% 1367918-21-5 250MG $560 2026-05-24 Buy
Product number Packaging Price Buy
BIPG1535 100mg $720 Buy
BIPG1535 250mg $1097 Buy
BIPG1535 1g $1831 Buy
bp-22395 100MG $360 Buy
bp-22395 250MG $560 Buy

Methylamino-PEG1-acid Chemical Properties, Uses, Production

Description

Methylamino-PEG1-acid is a PEG linker containing a carboxylic acid with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Methylamino-PEG1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methylamino-PEG1-acid Preparation Products And Raw materials

Raw materials

Preparation Products

Methylamino-PEG1-acid Suppliers

Global Suppliers ( 21)
Supplier Tel Email Country ProdList Advantage
Jinan elephant international trading co., LTD 13006575422@163.com China 6347 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. 13892832556 2440688701@qq.com China 1981 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Jilin Shengchuang Biotechnology Co., LTD 19975838191 396921152@qq.com China 166 58
Shandong fen Boyu Biotechnology Co.,LTD 13356310019 13356310019; boyu2024@163.com China 3947 58
Shanghai Zhiyun Biotechnology Co., Ltd 13119135307 China 2766 58
Jilin Shengchuang Biotechnology Co., LTD 13251734045; 13251734045 396921152@qq.com China 500 58
Methylamino-PEG1-acid Methylamino-PEG1-acid HCl salt Propanoic acid, 3-[2-(methylamino)ethoxy]- Me-NH-PEG1-CH2CH2COOH 1367918-21-5