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5-methoxy-2-methyl-2H-indazole

CAS No.
541539-88-2
Chemical Name:
5-methoxy-2-methyl-2H-indazole
Synonyms
5-methoxy-2-methyl-indazole;5-methoxy-2-methyl-2H-indazole;2H-Indazole, 5-methoxy-2-methyl-
CBNumber:
CB83126770
Molecular Formula:
C9H10N2O
Molecular Weight:
162.19
MDL Number:
MFCD16620002
MOL File:
541539-88-2.mol
MSDS File:
SDS
Last updated:2026-05-28 05:05:46

5-methoxy-2-methyl-2H-indazole Properties

storage temp. Sealed in dry,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

5-methoxy-2-methyl-2H-indazole price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 218954 5-Methoxy-2-methyl-2H-indazole 541539-88-2 1.00g $878 2026-05-18 Buy
Matrix Scientific 218954 5-Methoxy-2-methyl-2H-indazole 541539-88-2 5.00g $2520 2026-05-18 Buy
Synthonix M49721 5-Methoxy-2-methyl-2H-indazole 95+% 541539-88-2 250mg $64 2026-05-06 Buy
Synthonix M49721 5-Methoxy-2-methyl-2H-indazole 95+% 541539-88-2 1g $140 2026-05-06 Buy
Synthonix M49721 5-Methoxy-2-methyl-2H-indazole 95+% 541539-88-2 100mg $170 2026-05-06 Buy
Product number Packaging Price Buy
218954 1.00g $878 Buy
218954 5.00g $2520 Buy
M49721 250mg $64 Buy
M49721 1g $140 Buy
M49721 100mg $170 Buy

5-methoxy-2-methyl-2H-indazole Chemical Properties, Uses, Production

Synthesis

Trimethyloxonium Tetrafluoroborate

420-37-1

5-METHOXY-1H-INDAZOLE

94444-96-9

5-methoxy-2-methyl-2H-indazole

541539-88-2

To a solution of 5-methoxy-1H-indazole (1.0 g, 6.7 mmol) in ethyl acetate (10 mL) was added trimethoxonium tetrafluoroborate (1.3 g, 8.9 mmol). The reaction mixture was stirred at room temperature for 3 hours. After the reaction was completed, saturated aqueous sodium bicarbonate solution (10 mL) was added for neutralization and extracted with ethyl acetate (20 mL). The organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel fast column chromatography (petroleum ether/ethyl acetate = 2/1) to afford 5-methoxy-2-methyl-2H-indazole (0.64 g, 59% yield) as a yellow solid. Mass spectrometry analysis: [M + H]+ m/z calculated value (C9H10N2O) was 163, measured value was 163.

References

[1] Journal of Organic Chemistry, 2003, vol. 68, # 10, p. 4093 - 4095
[2] Patent: WO2016/44138, 2016, A1. Location in patent: Paragraph 00116
[3] Patent: WO2007/3419, 2007, A1. Location in patent: Page/Page column 69-72

420-37-1
94444-96-9
541539-88-2
Synthesis of 5-methoxy-2-methyl-2H-indazole from Trimethyloxonium Tetrafluoroborate and 5-Methoxy-1H-indazole

5-methoxy-2-methyl-2H-indazole Preparation Products And Raw materials

Raw materials

Preparation Products

5-methoxy-2-methyl-2H-indazole Suppliers

Global Suppliers ( 21)
Supplier Tel Email Country ProdList Advantage
Shanghai CP Pharmaceutical Technology Co., Ltd. 18221530285 China 488 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Wuxi AppTec 022-59987777 13552403979 jia_guoqiang@wuxiapptec.com China 22344 58
Aikon International Limited 025-66113011 19370895928 qzhang@aikonchem.com China 15390 58
3A Chemicals 400-668-9898 service@3achem.com China 20535 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Zhengzhou Convergence Chemical Co. LTD 13393710386 3941078109@qq.com China 9855 58
Hebei Weite Medical Technology Co., Ltd 13180081292 13180081292 contact@wetogethermed.com China 7712 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39796 58
PharmaBlock Sciences (Nanjing), Inc. 4000255188 sales_china@pharmablock.com China 9999 58
5-methoxy-2-methyl-2H-indazole 2H-Indazole, 5-methoxy-2-methyl- 5-methoxy-2-methyl-indazole 541539-88-2