7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline
- CAS No.
- 1609452-31-4
- Chemical Name:
- 7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline
- Synonyms
- Ethanone,1-[6-hydroxy-2,3-dimethoxy-9-(phenylmethoxy)phenyl]-;3,4-dihydro-2-(methylthio)-4-oxo-7-pyrimdineaceticacidethylester;7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline;7,8-Dibromo-2-chloro-5,6-dihydro-9-methyl-4H-imidazo[4,5,1-ij]quinoline;4H-Imidazo[4,5,1-ij]quinoline, 7,8-dibromo-2-chloro-5,6-dihydro-9-methyl-
- CBNumber:
- CB83376566
- Molecular Formula:
- C11H9Br2ClN2
- Molecular Weight:
- 364.46356
- MDL Number:
- MFCD28404968
- MOL File:
- 1609452-31-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA01EN1O | 7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline 95% | 1609452-31-4 | 100mg | $184 | 2026-05-30 | Buy |
| aablocks | AA01EN1O | 7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline 95% | 1609452-31-4 | 250mg | $404 | 2026-05-30 | Buy |
| Ambeed | A194767 | 7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline 95% | 1609452-31-4 | 100mg | $196 | 2021-12-16 | Buy |
| Ambeed | A194767 | 7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline 95% | 1609452-31-4 | 250mg | $390 | 2021-12-16 | Buy |
| Alichem | 1609452314 | 7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline | 1609452-31-4 | 100mg | $536 | 2021-12-16 | Buy |
7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline Chemical Properties, Uses, Production
Synthesis
1609453-56-6
1609452-31-4
7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-IJ]quinoline was synthesized as follows (Method 2A): 2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-IJ]quinoline (11.7 g, 56 mmol, Method 14A) was dissolved in acetonitrile (250 mL) pre-cooled to 0 °C in acetonitrile (250 mL). Subsequently, N-bromosuccinimide (50.0 g, 282 mmol) was added in batches over 1 hour. The reaction mixture was continued to be stirred at 0 °C for 30 min, after which it was brought to room temperature and stirred for 48 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in dichloromethane and washed with saturated aqueous sodium bicarbonate. The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated the filtrate to afford 18.6 g of the target product 7,8-dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-IJ]quinoline in 90% yield. The product was characterized by LC-MS (m/z 364.8 [M + 1]) and 1H NMR (600 MHz, DMSO) δ 4.12 (t, 2H, CH2), 2.88 (t, 2H, CH2), 2.57 (s, 3H, CH3), 2.22-2.18 (m, 2H, CH2).
References
[1] Patent: WO2014/72435, 2014, A1. Location in patent: Page/Page column 79


7,8-Dibromo-2-chloro-9-methyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| DebyeTec.com Inc. | 18086626237 18086626237 | 2693528373@qq.com | China | 2936 | 56 |
| Shanghai Amico Chemicals Co. LTD | 微信 18019252918 18019252918 | 1454668768@qq.com | China | 14933 | 58 |
| Shenyang Maud Pharmaceutical Technology Co., Ltd. | 024-23982345 | 1020788318@qq.com | China | 2246 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Jinan Dexinjia Bio&Tech Co., Ltd | 0531-82375880 15098789112 | 3845379039@qq.com | China | 1457 | 58 |
| Bide Pharmatech Ltd. | 400-6005915 | sales@picasso-e.com | China | 39645 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 17801761073 | Gsiyu@solarbio.com | China | 50460 | 58 |
| Hebei Yaocheng Pharmaceutical Technology Co. Ltd | 19903117580 19903117510 | yc-eliu@yaochengph.com | China | 9949 | 58 |
| Taizhou Chuanxu Pharmaceutical Technology Co., Ltd. | chuanxupharma@126.co | chuanxupharma@126.com | China | 9982 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13523716970 | Lingzhiyue@aliyun.com | China | 3137 | 58 |
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