EC 2.4.2.4
- CAS No.
- 9030-23-3
- Chemical Name:
- EC 2.4.2.4
- Synonyms
- TYMP;MNGIE;ECGF1;Gliostatin;EC 2.4.2.4;THYMIDINE PHOSPHORYLASE;Phosphorylase,thymidine;Thymidine Phosphorylase, recombinant;THYMIDINE PHOSPHORYLASE FROM*ESCHERICHIA COLI;ANTI-ECGF1 (CENTER) antibody produced in rabbit
- CBNumber:
- CB8341855
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00132426
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| WGK Germany | - |
| Storage Class | 12 - Non Combustible Liquids |
EC 2.4.2.4 price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T2807 | Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥500?units/mL | 9030-23-3 | 500units | $173 | 2026-04-30 | Buy |
| Sigma-Aldrich | T2807 | Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥500?units/mL | 9030-23-3 | 1000units | $222 | 2026-04-30 | Buy |
| Sigma-Aldrich | T6632 | Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥900?units/mL, aseptically filled | 9030-23-3 | 5000units | $1770 | 2026-04-30 | Buy |
| Sigma-Aldrich | T2807 | Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥500?units/mL | 9030-23-3 | 5000units | $757 | 2026-04-30 | Buy |
| Sigma-Aldrich | SRE0006 | Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, Suitable for manufacturing of diagnostic kits and reagents, buffered aqueous solution, ≥500?units/mL | 9030-23-3 | 5000units | $828 | 2026-04-30 | Buy |
EC 2.4.2.4 Chemical Properties, Uses, Production
Uses
Thymidine phosphorylase has been used in a study to evaluate biomarkers for advanced breast cancer patients treated with capecitabine-based first-line chemotherapy. Thymidine phosphorylase has also been used in a study to investigate implications for the clinical efficacy of nucleoside analogues.
Uses
Thymidine phosphorylase has been used in a study to assess TAS-102 treatment in patients with advanced solid tumors. Thymidine phosphorylase has also been used in a study to investigate antitumor effects of the FP3 protein on patient-derived tumor tissue xenograft models of primary colon carcinoma.
General Description
Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation.
Biochem/physiol Actions
An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays.
EC 2.4.2.4 Preparation Products And Raw materials
Raw materials
Preparation Products
EC 2.4.2.4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Dulai Biotechnology Co., Ltd. | 025-84699383-8003;025-846993838003-8003 18013301590 | njduly@126.com | China | 3293 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4688 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | shenlinxing@macklin.cn | China | 29676 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| Shanghai Guchen Biotechnology Co., LTD | 021-34675735 19147740836 | 1986399151@qq.com | China | 9839 | 58 |
| shlmai | 021-67680335 13052188602 | sale1@shlmai.net | China | 10000 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40048 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
