5-Amino-2-fluoropyridine
- CAS No.
- 1827-27-6
- Chemical Name:
- 5-Amino-2-fluoropyridine
- Synonyms
- 6-FLUOROPYRIDIN-3-AMINE;5-Amino-2-fL;6-FLUORO-3-PYRIDINAMINE;2-FLUOROPYRIDIN-5-AMINE;6-Fluoro-3-pyridineamine;3-Amino-6-fluoropyridine;5-AMINO-2-FLUOROPYRIDINE;5-Amine-2-fluoropyridine;2-FLUORO-5-AMINO PYRIDINE;3-PyridinaMine, 6-fluoro-
- CBNumber:
- CB8350068
- Molecular Formula:
- C5H5FN2
- Molecular Weight:
- 112.11
- MDL Number:
- MFCD01632180
- MOL File:
- 1827-27-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Amino-2-fluoropyridine 97% | 714593 | 1g | $77.2 |
| 5-Amino-2-fluoropyridine >98.0%(GC)(T) | A2384 | 1g | $69 |
| 5-Amino-2-fluoropyridine 98+% (GC) ≥98%(GC) | 233836 | 1g | $157 |
| 5-Amino-2-fluoropyridine 98+% (GC) ≥98%(GC) | 233836 | 5g | $199 |
| 5-Amino-2-fluoropyridine 98+% (GC) ≥98%(GC) | 233836 | 25g | $333 |
| More product size | |||
| Melting point | 86-87°C |
|---|---|
| Boiling point | 264.0±20.0 °C(Predicted) |
| Density | 1.257±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | powder to crystal |
| pka | 2+-.0.10(Predicted) |
| color | Purple to Dark purple to Dark red |
| InChI | 1S/C5H5FN2/c6-5-2-1-4(7)3-8-5/h1-3H,7H2 |
| InChIKey | YTHMOBMZVVFNBE-UHFFFAOYSA-N |
| SMILES | Nc1ccc(F)nc1 |
| CAS DataBase Reference | 1827-27-6(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H318-H335 | |||||||||
| Precautionary statements | P280-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-41-37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
5-Amino-2-fluoropyridine price More Price(93)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 714593 | 5-Amino-2-fluoropyridine 97% | 1827-27-6 | 1g | $77.2 | 2026-04-30 | Buy |
| TCI Chemical | A2384 | 5-Amino-2-fluoropyridine >98.0%(GC)(T) | 1827-27-6 | 1g | $69 | 2026-04-30 | Buy |
| Usbiological | 233836 | 5-Amino-2-fluoropyridine 98+% (GC) ≥98%(GC) | 1827-27-6 | 1g | $157 | 2026-06-03 | Buy |
| Usbiological | 233836 | 5-Amino-2-fluoropyridine 98+% (GC) ≥98%(GC) | 1827-27-6 | 5g | $199 | 2026-06-03 | Buy |
| Usbiological | 233836 | 5-Amino-2-fluoropyridine 98+% (GC) ≥98%(GC) | 1827-27-6 | 25g | $333 | 2026-06-03 | Buy |
5-Amino-2-fluoropyridine Chemical Properties,Uses,Production
Chemical Properties
Light yellow Cryst
Uses
5-Amino-2-fluoropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
456-24-6
1827-27-6
General procedure for the synthesis of 2-fluoro-5-aminopyridine from 2-fluoro-5-nitropyridine: 50 mL of toluene and 50 mmol of 2-fluoro-5-nitropyridine were added to a 100 mL round-bottomed flask, followed by 0.282 g of 5% Pd/C catalyst and 10 mmol of anhydrous sodium sulfate. The reaction system was placed under hydrogen atmosphere, heated and stirred for 15 hours. Upon completion of the reaction, the mixture was cooled to room temperature, the catalyst was removed by filtration and the filtrate was concentrated by rotary evaporation. The resulting crude product was purified by recrystallization and finally dried under vacuum to give 1.6806 g of 2-fluoro-5-aminopyridine solid in 75% yield.
References
[1] Journal of the Chemical Society - Perkin Transactions 1, 1996, # 18, p. 2221 - 2226
[2] Patent: CN103755744, 2016, B. Location in patent: Paragraph 0065; 0066
[3] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 6, p. 1411 - 1416
[4] Patent: US6355636, 2002, B1. Location in patent: Page column 64
[5] Patent: EP1171440, 2004, B1. Location in patent: Page 53
5-Amino-2-fluoropyridine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Changzhou Carman Chemical Co., Ltd. | 15061933924 | CHINA | 514 | 58 | |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from 5-Amino-2-fluoropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | 5-Amino-2-fluoropyridine
1827-27-6
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-09-25 | 5-Amino-2-fluoropyridine
1827-27-6
|
$1.00-200.00 | 1KG | 99%, 99.5% Sublimated | Henan Fengda Chemical Co., Ltd | ||
 |
2025-06-27 | 5-Amino-2-fluoropyridine
1827-27-6
|
$10.00-30.00 | 50KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 5-Amino-2-fluoropyridine
1827-27-6
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 5-Amino-2-fluoropyridine
1827-27-6
- $1.00-200.00
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- 5-Amino-2-fluoropyridine
1827-27-6
- $10.00-30.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
