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1-N-BOC-PIPERIDINE-3-CARBOXAMIDE

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE structure

CAS No.: 91419-49-7

Chemical Name:: 1-N-BOC-PIPERIDINE-3-CARBOXAMIDE

Synonyms: 3-CARBAMOYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;BOC-3-Piperidine carboxamide;N-BOC-3-PiperidineCarboxamide;1-Boc-3-piperidinecarboxamide;1-N-BOC-3-CARBAMOYLPIPERIDINE;N-BOC-piperidine-3-carboxamide;1-Boc-piperidine-3-carboxamide;1-N-Boc-3-piperidinecarboxamide;1-N-BOC-PIPERIDINE-3-CARBOXAMIDE;1-Boc-3-(aMinocarbonyl)-piperidine

CBNumber:: CB8359834

Molecular Formula:: C11H20N2O3

Molecular Weight:: 228.29

MDL Number:: MFCD06658365

MOL File:: 91419-49-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 03:22:01

Product description	Number	Pack Size	Price
1-(tert-Butoxycarbonyl)-3-piperidinecarboxamide >98.0%(GC)	B5292	1g	$32
1-(tert-Butoxycarbonyl)-3-piperidinecarboxamide >98.0%(GC)	B5292	5g	$108
1-N-Boc-piperidine-3-carboxamide Asreported	265816	500mg	$333
1-N-Boc-piperidine-3-carboxamide Asreported	265816	1g	$472
1-N-Boc-piperidine-3-carboxamide Asreported	265816	2g	$633
More product size

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1-N-BOC-PIPERIDINE-3-CARBOXAMIDE Properties

Melting point	174.0 to 178.0 °C
Boiling point	384.4±31.0 °C(Predicted)
Density	1.123±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	soluble in Methanol
form	powder to crystal
pka	16.41±0.20(Predicted)
color	White to Almost white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H315-H335
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Risk Statements	22
Safety Statements	37
HS Code	29333990

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE price More Price(67)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B5292	1-(tert-Butoxycarbonyl)-3-piperidinecarboxamide >98.0%(GC)	91419-49-7	1g	$32	2026-04-30	Buy
TCI Chemical	B5292	1-(tert-Butoxycarbonyl)-3-piperidinecarboxamide >98.0%(GC)	91419-49-7	5g	$108	2026-04-30	Buy
Usbiological	265816	1-N-Boc-piperidine-3-carboxamide Asreported	91419-49-7	500mg	$333	2026-06-03	Buy
Usbiological	265816	1-N-Boc-piperidine-3-carboxamide Asreported	91419-49-7	1g	$472	2026-06-03	Buy
Usbiological	265816	1-N-Boc-piperidine-3-carboxamide Asreported	91419-49-7	2g	$633	2026-06-03	Buy

Product number	Packaging	Price	Buy
B5292	1g	$32	Buy
B5292	5g	$108	Buy
265816	500mg	$333	Buy
265816	1g	$472	Buy
265816	2g	$633	Buy

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE Chemical Properties,Uses,Production

Chemical Properties

White powder

Synthesis Reference(s)

Synthetic Communications, 20, p. 1203, 1990 DOI: 10.1080/00397919008052828

Synthesis

71381-75-4

91419-49-7

General procedure for the synthesis of N-BOC-3-piperidinecarboxamide from 1-BOC-piperidine-3-carboxylic acid: To a chloroform solution (10 mL) of 1-Boc-piperidine-3-carboxylic acid (1.58 g, 6.89 mmol) was added drop-wise at 0 °C and under nitrogen protection, triethylamine (0.96 mL, 6.89 mmol) and ethyl chloroformate (0.69 mL, 7.23 mmol). The reaction mixture was stirred at 0°C for 10 min and then ammonia (gas) was passed for 1 hr. Subsequently, the reaction mixture was warmed to room temperature and stirring was continued for 3 hours. Upon completion of the reaction, 5% aqueous sodium bicarbonate solution was added to separate the organic and aqueous phases. The organic layer was dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude N-BOC-3-piperidinecarboxamide, which can be used in subsequent reactions without further purification. Yield: quantitative; LCMS (retention time): 3.31 min (Method A); mass spectrometry (electrospray positive ionization mode) showed m/z: 229.0 ([M+H]+).

References

[1] Patent: WO2006/123257, 2006, A2. Location in patent: Page/Page column 34
[2] Patent: US8080566, 2011, B1. Location in patent: Page/Page column 37-38
[3] European Journal of Medicinal Chemistry, 1984, vol. 19, # 2, p. 181 - 186
[4] Journal of Medicinal Chemistry, 2007, vol. 50, # 9, p. 2225 - 2239
[5] Patent: WO2014/149164, 2014, A1. Location in patent: Paragraph 00605

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE Preparation Products And Raw materials

Raw materials

1-BOC-PIPERIDINE-3-CARBOXYLIC ACID NIPECOTAMIDE Di-tert-butyl dicarbonate Ammonia Ethyl chloroformate

Triethylamine

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Preparation Products

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE Suppliers

Global( 118)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88298848	info@edengenechem.com	China	2165	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Baoji Guokang Healthchem co.,ltd	+8615604608665 15604608665	dominicguo@gk-bio.com	CHINA	9414	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58

Supplier	Advantage
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Changzhou Ditong Chemical Co.,Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Baoji Guokang Healthchem co.,ltd	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from 1-N-BOC-PIPERIDINE-3-CARBOXAMIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-02	1-N-Boc-3-Carbamoyl-piperidine 91419-49-7	$6.00-10.00	1kg	99%	5000 Metric Ton/Month	Wuhan Xinhao Biotechnology Co., Ltd
2023-07-31	1-N-BOC-PIPERIDINE-3-CARBOXAMIDE 91419-49-7	$20.00	10kg	99%	20tons	Hebei Linwo New Material Technology Co., LTD
2019-09-02	1-N-BOC-PIPERIDINE-3-CARBOXAMIDE 91419-49-7	$7.00	1KG	99%		Career Henan Chemical Co

1-N-Boc-3-Carbamoyl-piperidine
91419-49-7
$6.00-10.00
99%
Wuhan Xinhao Biotechnology Co., Ltd

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE
91419-49-7
$20.00
99%
Hebei Linwo New Material Technology Co., LTD

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE
91419-49-7
$7.00
99%
Career Henan Chemical Co

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE Spectrum

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE(91419-49-7)¹HNMR

91419-49-7(1-N-BOC-PIPERIDINE-3-CARBOXAMIDE)Related Search:

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1-N-BOC-PIPERIDINE-3-CARBOXAMIDE 1-N-Boc-3-piperidinecarboxamide 1-TERT-BUTOXYCARBONYL-3-METHYLAMINOPIPERIDINE 1-Boc-piperidine-3-carboxamide 1-Piperidinecarboxylic acid, 3-(aminocarbonyl)-, 1,1-dimethylethyl ester 1-N-BOC-3-CARBAMOYLPIPERIDINE tert-butyl 3-(aminocarbonyl)piperidine-1-carboxylate 1-Boc-3-piperidinecarboxamide N-BOC-3-PiperidineCarboxamide BOC-3-Piperidine carboxamide N-BOC-piperidine-3-carboxamide tert-butyl 3-carbaMoylpiperidine-1-carboxylate 1-Boc-3-(aMinocarbonyl)-piperidine 1-(tert-Butoxycarbonyl)-3-piperidinecarboxamide 3-Carbamoyl-1-piperidinecarboxylic Acid tert-Butyl Ester tert-Butyl 3-Carbamoyl-1-piperidinecarboxylate 1-Piperidinecarboxylic acid, 3-(aminocarbonyl)-, 1,1-dimethy... 3-CARBAMOYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 91419-49-7