6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
- CAS No.
- 55052-27-2
- Chemical Name:
- 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
- Synonyms
- 6-CHLORO-7-AZAINDOLE;6-chloro-;o[2,3-b]pyridine;6-Chloro-7-azaindole,95%;2-Chloro-7H-pyrrolo[2,3-b]pyridine;6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE;1H-Pyrrolo[2,3-b]pyridine, 6-chloro-;6-Chloro-1H-pyrrolido [2,3-B] pyridine;6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE ISO 9001:2015 REACH
- CBNumber:
- CB8360793
- Molecular Formula:
- C7H5ClN2
- Molecular Weight:
- 152.58
- MDL Number:
- MFCD06659666
- MOL File:
- 55052-27-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Chloro-1H-pyrrolo[2,3-b]pyridine | B418665 | 5g | $150 |
| 6-Chloro-1H-pyrrolo[2,3-b]pyridine | OR301275 | 5g | $174 |
| 6-Chloro-7-azaindole | V2201 | 10g | $181 |
| 6-Chloro-7-azaindole | FC140689 | 2g | $100 |
| 6-Chloro-1H-pyrrolo[2,3-b]pyridine 95% | 070121 | 5g | $140 |
| More product size | |||
| Melting point | 170-175℃ |
|---|---|
| Boiling point | 420.7±37.0 °C(Predicted) |
| Density | 1.42±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 6.76±0.40(Predicted) |
| form | Powder |
| color | White to pale brown |
| InChI | InChI=1S/C7H5ClN2/c8-6-2-1-5-3-4-9-7(5)10-6/h1-4H,(H,9,10) |
| InChIKey | DSCOSIUAQUDGJM-UHFFFAOYSA-N |
| SMILES | C12NC=CC1=CC=C(Cl)N=2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| RIDADR | UN2811 | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B418665 | 6-Chloro-1H-pyrrolo[2,3-b]pyridine | 55052-27-2 | 5g | $150 | 2021-12-16 | Buy |
| Apolloscientific | OR301275 | 6-Chloro-1H-pyrrolo[2,3-b]pyridine | 55052-27-2 | 5g | $174 | 2021-12-16 | Buy |
| AK Scientific | V2201 | 6-Chloro-7-azaindole | 55052-27-2 | 10g | $181 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC140689 | 6-Chloro-7-azaindole | 55052-27-2 | 2g | $100 | 2021-12-16 | Buy |
| Matrix Scientific | 070121 | 6-Chloro-1H-pyrrolo[2,3-b]pyridine 95% | 55052-27-2 | 5g | $140 | 2021-12-16 | Buy |
6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE Chemical Properties,Uses,Production
Uses
6-Chloro-1H-pyrrolo[2,3-b]pyridine is used in the preparation of heterocyclic compounds for the use of treatment of cancer.
Synthesis
849068-50-4
55052-27-2
Example 96 Step C: Synthesis of 6-chloro-1H-pyrrolo[2,3-B]pyridine. Ethyl 6-chloro-pyrrolo[2,3-B]pyridine-1-carboxylate (400 mg, 1.78 mmol) was dissolved in methanol (35 mL), followed by the addition of 1N sodium hydroxide solution (13 mL). The reaction mixture was stirred at room temperature for 6 hours. Upon completion of the reaction, the solvent was removed by rotary evaporator. The residue was neutralized with saturated sodium bicarbonate solution and the precipitate was collected by filtration. The precipitate was washed with water and dried by vacuum pump to afford the target product 6-chloro-1H-pyrrolo[2,3-B]pyridine (260 mg, 1.71 mmol, 96% yield). MS (electrospray positive ion mode): m/e = 153.1 ([M+H]+); LC retention time: 2.85 min.
References
[1] Patent: WO2005/28475, 2005, A2. Location in patent: Page/Page column 175
[2] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 23, p. 7107 - 7112
[3] Patent: WO2013/10880, 2013, A1. Location in patent: Page/Page column 103-104
[4] Patent: EP2548876, 2013, A1. Location in patent: Paragraph 0438-0441
[5] Patent: WO2016/112088, 2016, A1. Location in patent: Paragraph 0447
6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13590 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29796 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
55052-27-2
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
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2023-04-12 | 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
55052-27-2
|
US $15.00 / Kg/Bag | 1Kg/Bag | 99.8% | Weekly supply of 1000KG | Wuhan Dujiang Industrial Co., Ltd. | |
![]() |
2021-10-15 | 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
55052-27-2
|
US $10.00 / KG | 1KG | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd |
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![6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE pictures](/ProductImageEN/2021-10/Small/8ae62a31-67a1-4014-9ad5-b6b402bb413b.jpg)
- 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
55052-27-2
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
![6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE pictures](/ProductImageEN/2022-05/Small/2cb57d7d-52a1-4846-b026-bbe9d7072e98.png)
- 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
55052-27-2
- US $15.00 / Kg/Bag
- 99.8%
- Wuhan Dujiang Industrial Co., Ltd.
-
![6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE pictures](/ProductImageEN/2021-10/Small/15ffabc0-384e-4474-b9c5-032b6055f69c.jpg)
- 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE
55052-27-2
- US $10.00 / KG
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
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