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Androstenedione

Androstenedione Structure
Androstenedione structure
CAS No.
63-05-8
Chemical Name:
Androstenedione
Synonyms
4-AD;4-ANDROSTENEDIONE;4-ANDROSTENE-3,17-DIONE;ANDROSTENDIONE;ANDROSTA-4-ENE-3,17-DIONE;Androstenedione (CRM);skf2170;ANDROTEX;SKF 2170;Fecundin
CBNumber:
CB8365581
Molecular Formula:
C19H26O2
Molecular Weight:
286.41
MDL Number:
MFCD00003615
MOL File:
63-05-8.mol
MSDS File:
SDS
Last updated:2026-04-10 10:27:30
Product description Number Pack Size Price
4-Androstenedione ≥98% (HPLC) SML2364 250MG $67.6
4-Androstenedione ≥98% (HPLC) SML2364 500MG $129
Testosterone Related Compound A certified reference material, pharmaceutical secondary standard PHR8811 50 mg $559
Androstenedione phyproof? Reference Substance PHL89562 100MG $192
Androstenedione solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? A-075 1mL $54.9
More product size
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Androstenedione Properties

Melting point 170-171 °C(lit.)
alpha D30 +199° (in chloroform)
Boiling point 368.77°C (rough estimate)
Density 1.0655 (rough estimate)
refractive index 1.4709 (estimate)
Flash point 2℃
storage temp. Controlled Substance, -20°C Freezer
solubility Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Sparingly)
form Solid
color Dimorphous: Needles from acetone, or crystalsfrom hexane
Water Solubility 57.28mg/L(25 ºC)
Merck 13,643
Henry's Law Constant 2.7×102 mol/(m3Pa) at 25℃, HSDB (2015)
InChI 1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
InChIKey AEMFNILZOJDQLW-QAGGRKNESA-N
SMILES [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)C(=O)CC[C@@]24[H]
Toxicology and Carcinogenesis Toxicology and Carcinogenesis Studies of Androstenedione (CASRN 63-05-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
CAS DataBase Reference 63-05-8(CAS DataBase Reference)
FDA UNII 409J2J96VR
NIST Chemistry Reference Androst-4-ene-3,17-dione(63-05-8)
Proposition 65 List Androstenedione
EPA Substance Registry System 4-Androstenedione (63-05-8)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302+H312+H332-H319
Precautionary statements  P210-P261-P280-P305+P351+P338-P370+P378-P403+P235
Hazard Codes  Xn,T,F
Risk Statements  40-64-52-22-61-60-36-20/21/22-11
Safety Statements  22-24/25-36-45-36/37-53-26-16
RIDADR  UN 1648 3 / PGII
WGK Germany  3
RTECS  BV8150000
HS Code  29372900
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 4 Oral
Carc. 2
Lact.
Repr. 1A
Hazardous Substances Data 63-05-8(Hazardous Substances Data)
NFPA 704
1
2 0

Androstenedione price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2364 4-Androstenedione ≥98% (HPLC) 63-05-8 250MG $67.6 2026-04-30 Buy
Sigma-Aldrich SML2364 4-Androstenedione ≥98% (HPLC) 63-05-8 500MG $129 2026-04-30 Buy
Sigma-Aldrich PHR8811 Testosterone Related Compound A certified reference material, pharmaceutical secondary standard 63-05-8 50 mg $559 2026-04-30 Buy
Sigma-Aldrich PHL89562 Androstenedione phyproof? Reference Substance 63-05-8 100MG $192 2026-04-30 Buy
Sigma-Aldrich A-075 Androstenedione solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? 63-05-8 1mL $54.9 2026-04-30 Buy
Product number Packaging Price Buy
SML2364 250MG $67.6 Buy
SML2364 500MG $129 Buy
PHR8811 50 mg $559 Buy
PHL89562 100MG $192 Buy
A-075 1mL $54.9 Buy

Androstenedione Chemical Properties,Uses,Production

Biological Metabolism

The in vitro perfusion of the human placental lobule with 7-ethoxycoumarin gives 7-hydroxycoumarin, and perfusion with androstenedione gives the conversion products, estrone, estradiol, and testosterone. The human placenta has only a limited capacity for the metabolism of xenobiotics.

Description

Androstenedione (CRM) (Item No. ISO60161) is a certified reference material categorized as an anabolic androgenic steroid. Androstenedione is a precursor of testosterone (Item Nos. ISO60154 | ISO00154 | 15645) and estrone . Androstenedione is regulated as a Schedule III compound in the United States. Androstenedione (CRM) (Item No. ISO60161) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Chemical Properties

White to Off-White Solid

Uses

Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)

Definition

ChEBI: A 3-oxo Delta4-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads.

Safety Profile

An experimental teratogen. Otherexperimental reproductive effects. Questionablecarcinogen with experimental tumorigenic data. Whenheated to decomposition it emits acrid smoke andirritating fumes.

Purification Methods

Crystallise the dione from hexane. It is soluble in *C6H6, CHCl3 and EtOH. It has max at 239nm. It is a precursor of estrone or testosterone and has androgenic activity. [Ruzicka & Wettstein Helv Chim Acta 18 980 1935, Beilstein 7 III 3636, 7 IV 2381.]

Toxics Screening Level

The initial threshold screening level (ITSL) for androstenedione is 17 μg/m3 based on an annual averaging time.

References

[1] F. CHEN. Partial agonist/antagonist properties of androstenedione and 4-androsten-3β,17β-diol[J]. Journal of Steroid Biochemistry and Molecular Biology, 2004, 91 4: Pages 247-257. DOI: 10.1016/j.jsbmb.2004.04.009
[2] Toxicology and carcinogenesis studies of androstenedione (CAS No. 63-05-8) in F344/N rats and B6C3F1 mice (gavage studies).[J]. National Toxicology Program technical report series, 2010, 560: 1, 7-31,33-171 passim.
[3] OSTOJI S, CALLEJA-GONZáLEZ J, STOJANOVI M. Steroid Prohormones: Effects on Body Composition in Athletes[C]. 2011: 0. DOI: 10.5772/28543

Androstenedione synthesis

58-22-0
63-05-8
Synthesis of Androstenedione from Testosterone

Androstenedione Preparation Products And Raw materials

Raw materials

beta-Sitosterol 3-keto-23,24-bisnorchol-4-en-22-ol CAMPESTEROL Cholesterol (8S,9R,10S,13S,14S,17S)-9,17-dihydroxy-10,13-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one

Preparation Products

Spironolactone 5B-ANDROSTANE-3,17-DIONE Androsta-1,4-diene-3,17-dione Testosterone undecanoate Androst-3-en-17-one,(5)
5α-Androstane-3,6,17-trione 11α-Hydroxyandrost-4-ene-317-dione Methyl 3-oxo-4-androstene-17beta-carboxylate 6-Methyleneandrost-4-ene-3,17-dione

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Androstenedione Suppliers

Global( 319)Suppliers
Supplier Tel Email Country ProdList Advantage
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd.
+86-029-86185165 +8618629664246 guoyuan@eastchinapharm.com China 1615 58
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Nantong Guangyuan Chemicl Co,Ltd 		+undefined17712220823 admin@guyunchem.com China 615 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29819 58
Shanghai Worldyang Chemical Co.,Ltd. 		+86-021-56795779 +8613651600618 sales@worldyachem.com China 967 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Shanghai Standard Technology Co., Ltd. 		18502101150 ft-sales@nature-standard.com CHINA 1923 58
Hebei shuoxi biotechnology co. LTD 		+8613081092107 CHINA 964 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-87569262 +86-15003564040 1056@dideu.com China 3982 58
Antai Fine Chemical Technology Co.,Limited 		18503026267 info@antaichem.com CHINA 9636 58
Supplier Advantage
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd.
58
Hebei Yanxi Chemical Co., Ltd. 		58
Nantong Guangyuan Chemicl Co,Ltd 		58
career henan chemical co 		58
Shanghai Worldyang Chemical Co.,Ltd. 		58
Standardpharm Co. Ltd. 		58
Shanghai Standard Technology Co., Ltd. 		58
Hebei shuoxi biotechnology co. LTD 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Antai Fine Chemical Technology Co.,Limited 		58

Related articles

View Lastest Price from Androstenedione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Androstenedione pictures 2026-05-03 Androstenedione
63-05-8
 0.99 RongNa Biotechnology Co.,Ltd
4-Androstenedione pictures 2025-12-25 4-Androstenedione
63-05-8
 US $0.00-0.00 / KG 1KG 99% 5000KG Wuhan Biocar Pharmacy CO.,Ltd.
Androstenedione pictures 2025-06-20 Androstenedione
63-05-8
 US $40.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.

Androstenedione Spectrum

Androstenedione(63-05-8)MSAndrostenedione(63-05-8)13CNMRAndrostenedione(63-05-8)IR1

63-05-8(Androstenedione)Related Search:

Androstenedione-3,17-Dione 6-METHYLENEANDROST-4-ENE-3,17-DIONE 2,2-Dimethyl-1,3-propanediol 1-ChloroMethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) 1-Bromopentane
Bromoacetonitrile PotassiuM triMethylacetate, 95% ZINC-COPPER COUPLE Exemestane Impurity 13 Exemestane impurity B -F
17-Beta-Hydroxy Exemestane Epoxide Androstenediol Exemestane 6-Oxo Boldione ExeMestane Related CoMpound
Exemestane Impurity 1 Exemestane Impurity 11 androstane-3,6,17-triol

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3,17-Dioxoandrost-4-Ene Androstenedione (CRM) Testosterone EP Impurity A 4-Androstene-3 4-androsten-3,17-dione (4-AD) 4-Androstene-3,17-dione Solution, 100ppm Androstenedione solution 4-androstene-3,17-dione(4-AD) Androstenedione solution,100ppm (8R,9S,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione (8R,9S,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-quinone (8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione (+)-4-ANDROSTEN-3,17-DIONE 4-ANDROSTEN-3,17-DIONE ANDROTEX ANDROSTENEDIONE ANDROST-4-ENE-3, 17-DIONE ANDROST-4-ENE-3,17-DIONE, 10,13-DIMETHYL-2,6,7,8,9,11,12,14,15,16-DECAHYDRO-1H-CYCLOPENTA[A]PHENANTHRENE-3,17-DIONE ANDROSTA-4-ENE-3,17-DIONE delta-(sup4)-Androsten-3,17-dione delta(Sup4)-Androstene-3,17-dione delta4-androsten-3,17-dione delta-4-androstenedione SKF 2170 skf2170 (8R,9S,10R,13S,14S)-10,13-DIMETHYL-1,6,7,8,9,10,11,12,13,14,15,16-DODECAHYDRO-2H-CYCLOPENTA[A]PHENANTHRENE-3,17-DIONE 3,17-DIOXO-4-ANDROSTENE Androsten-3,17-dione Androstenedione (JAN) Androstenedione 4-AD Androstenedione 10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]ph 10,13-Dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-dione Testosterone Impurity 1(Testosterone EP Impurity A) 10,13-DIMETHYL-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHRENE-3,17-DIONE 4-Androstenedione(4AD) 17-Ketotestosterone Fecundin NSC 9563 ndrostenedione 10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione ANDROSTENEDIONE(SH) 4-ANDROSTENEDIONE(ANDROSTENEDIONE) DELTA-ANDROSTEN-3,17-DIONE DELTA4-ANDROSTENE-3,17-DIONE 4-ANDROSTENE-3,1,7-DIONE, FROM DIOSCOREA OPPOSITA THUNB.99%(HPLC) 4-ANDROSTENE-3,17-DIONE 98.5+% 4-ANDROSTENEDIONE 99% MIN (4-AD)4-ANDROSTENEDIONE 4-ANDROSTENEDIONE (4-ANDROSTENE-3,17-DIONE) Androst-4-endione 4-androstenedione(biological method)4-AD 7-Oxo-Dehydroepiandrosterone(7-OXO-DHEA) Androst-4-ene-3,17-dione (Androsten Androstenedione,HPLC≥98% Androstenedione standard solution, 100ppm Exemestane Impurity 5-d7 Androstenedione- D7Q: What is Androstenedione- D7 Q: What is the CAS Number of Androstenedione- D7 Testosterone Related Compound A CIII (Androst-4-ene-3,17-dione) (1646010) Testosterone Related Compound A