Triethylene glycol monobenzyl ether
- CAS No.
- 55489-58-2
- Chemical Name:
- Triethylene glycol monobenzyl ether
- Synonyms
- BnO-PEG3-OH;2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethan-1-ol;Benzyl-PEG3-OH;CAS_55489-58-2;HO-(CH2CH2O)3-Bn;TEGmonobenzylether;RARECHEM AH CK 0201;TRIETHYLENEGLYKOLMONOBENZYLETHER;Triethyleneglykolmonobenzyl ethe;TRIETHYLENEGLYCOLMONOBENZYL ETHER
- CBNumber:
- CB8371935
- Molecular Formula:
- C13H20O4
- Molecular Weight:
- 240.3
- MDL Number:
- MFCD02093556
- MOL File:
- 55489-58-2.mol
- MSDS File:
- SDS
| Boiling point | 131 °C |
|---|---|
| Density | 1.09 |
| refractive index | 1.5050 to 1.5080 |
| storage temp. | Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | 14.36±0.10(Predicted) |
| color | Colorless to Light yellow to Light orange |
| InChI | InChI=1S/C13H20O4/c14-6-7-15-8-9-16-10-11-17-12-13-4-2-1-3-5-13/h1-5,14H,6-12H2 |
| InChIKey | KVPHZILZNXDCNH-UHFFFAOYSA-N |
| SMILES | C(O)COCCOCCOCC1=CC=CC=C1 |
| CAS DataBase Reference | 55489-58-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Hazard Note | Irritant |
| HS Code | 2909199090 |
Triethylene glycol monobenzyl ether price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T1996 | Triethylene Glycol Monobenzyl Ether >97.0%(GC) | 55489-58-2 | 5g | $165 | 2026-04-30 | Buy |
| TCI Chemical | T1996 | Triethylene Glycol Monobenzyl Ether >97.0%(GC) | 55489-58-2 | 25g | $657 | 2026-04-30 | Buy |
| ChemScene | CS-0037462 | Triethylene glycol monobenzyl ether ≥95% | 55489-58-2 | 5g | $13 | 2026-06-04 | Buy |
| ChemScene | CS-0037462 | Triethylene glycol monobenzyl ether ≥95% | 55489-58-2 | 10g | $15 | 2026-06-04 | Buy |
| ChemScene | CS-0037462 | Triethylene glycol monobenzyl ether ≥95% | 55489-58-2 | 25g | $29 | 2026-06-04 | Buy |
Triethylene glycol monobenzyl ether Chemical Properties, Uses, Production
Description
Benzyl-PEG4-alcohol is a PEG linker with an acid labile, benzyl protecting group and a reactive primary alcohol. The primary alcohol can react and further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Uses
Triethylene Glycol Monobenzyl Ether is used in the preparation of self-assembled monolayers with multiple binding sites and biocompatible imprinted cavities for biosensor application. Also used in the synthesis of novel ethoxylated inositol surfactants.
Synthesis
100-44-7
112-27-6
55489-58-2
Triethylene glycol (30 g, 0.2 mol) was dissolved in aqueous sodium hydroxide solution (8 g NaOH dissolved in 8 mL H2O) and stirred for 10 minutes. Subsequently, benzyl chloride (7 mL, 0.062 mol) was slowly added to the reaction system, and the reaction mixture was heated to 100 °C and stirred continuously overnight. Upon completion of the reaction, the crude product was diluted with saturated sodium chloride solution (500 mL) and subsequently extracted with dichloromethane (2 x 400 mL). The organic layers were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. Purification by column chromatography (silica gel as stationary phase, eluent ethyl acetate to ethyl acetate/methanol, 10:1, v/v/v) afforded the light yellow oily target product triglyceride monobenzyl ether (9.87 g, 67% yield).
IC 50
PEGs
References
[1] European Journal of Organic Chemistry, 2008, # 17, p. 2900 - 2914
[2] Journal of the American Chemical Society, 2013, vol. 135, # 25, p. 9248 - 9251
[3] Synthetic Communications, 1986, vol. 16, # 1, p. 19 - 26
[4] Tetrahedron Letters, 2001, vol. 42, # 23, p. 3819 - 3822
[5] Patent: US2008/207505, 2008, A1. Location in patent: Page/Page column 31
Triethylene glycol monobenzyl ether Preparation Products And Raw materials
Triethylene glycol monobenzyl ether Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Annular（Qihe）New Material Technology Co., Ltd | 18600642180（微信同） 13391601435 | 1584468135@qq.com | China | 2037 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Beijing Isomersyn Technology CO;LTD | 010-82954736 13391601435 | sales@isomersyn.com | China | 3294 | 57 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Latest Price from Triethylene glycol monobenzyl ether manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-29 | Triethylene glycol monobenzyl ether
55489-58-2
|
10g | TargetMol Chemicals Inc. | ||||
 |
2026-07-24 | 2-(2-(2-(benzyloxy)ethoxy)ethoxy)ethanol
55489-58-2
|
1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. | ||
 |
2026-01-28 | BnO-PEG3-OH
55489-58-2
|
1g | 98% | 300kg | LAURENT |
-
- Triethylene glycol monobenzyl ether
55489-58-2
- $0.00
- TargetMol Chemicals Inc.
-
- 2-(2-(2-(benzyloxy)ethoxy)ethoxy)ethanol
55489-58-2
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
-
- BnO-PEG3-OH
55489-58-2
- 98%
- LAURENT
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