Ethyl 2-hydroxyisobutyrate
- CAS No.
- 80-55-7
- Chemical Name:
- Ethyl 2-hydroxyisobutyrate
- Synonyms
- Ethyl α-hydroxyisobu;ETHYL 2-METHYLLACTATE;Ethyl hydroxyisobtyrate;Ethyl hydroxyisobutyrate;Ethyl α-hydroxyisobutyra;ETHYL 2-HYDROXYISOBUTYRATE;Ethyl α-hydroxyisobutyrate;Ethyl 2-hydroxyisobutanoate;Ethyl-a-hydroxy-iso-butyrate;2-methyl-lacticaciethylester
- CBNumber:
- CB8376602
- Molecular Formula:
- C6H12O3
- Molecular Weight:
- 132.16
- MDL Number:
- MFCD00004458
- MOL File:
- 80-55-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 2-Hydroxyisobutyrate >98.0%(GC) | H0255 | 25g | $58 |
| Ethyl 2-Hydroxyisobutyrate >98.0%(GC) | H0255 | 250g | $271 |
| Ethyl 2-Hydroxyisobutyrate | E937898 | 1g | $45 |
| Ethyl2-hydroxyisobutanoate >95% | 127269 | 100g | $50 |
| Ethylalpha-hydroxyisobutyrate 98% | JK460065 | 500g | $499 |
| More product size | |||
| Melting point | 78 °C |
|---|---|
| Boiling point | 150 °C (lit.) |
| Density | 0.965 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 112 °F |
| storage temp. | Flammables area |
| pka | 13.28±0.29(Predicted) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| BRN | 878308 |
| InChI | InChI=1S/C6H12O3/c1-4-9-5(7)6(2,3)8/h8H,4H2,1-3H3 |
| InChIKey | GFUIDHWFLMPAGY-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)C(O)(C)C |
| CAS DataBase Reference | 80-55-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | S1530MCV3X |
| NIST Chemistry Reference | Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester(80-55-7) |
| EPA Substance Registry System | Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester (80-55-7) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226 | |||||||||
| Precautionary statements | P210-P370+P378 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 10-36/37/38-36/38 | |||||||||
| Safety Statements | 26-36-16 | |||||||||
| RIDADR | UN 3272 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | OD5672000 | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29181980 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Flam. Liq. 3 | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
Ethyl 2-hydroxyisobutyrate price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | H0255 | Ethyl 2-Hydroxyisobutyrate >98.0%(GC) | 80-55-7 | 25g | $58 | 2025-07-31 | Buy |
| TCI Chemical | H0255 | Ethyl 2-Hydroxyisobutyrate >98.0%(GC) | 80-55-7 | 250g | $271 | 2025-07-31 | Buy |
| TRC | E937898 | Ethyl 2-Hydroxyisobutyrate | 80-55-7 | 1g | $45 | 2021-12-16 | Buy |
| Matrix Scientific | 127269 | Ethyl2-hydroxyisobutanoate >95% | 80-55-7 | 100g | $50 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK460065 | Ethylalpha-hydroxyisobutyrate 98% | 80-55-7 | 500g | $499 | 2021-12-16 | Buy |
Ethyl 2-hydroxyisobutyrate Chemical Properties,Uses,Production
Description
Ethyl 2-hydroxyisobutyrate (E-2HIBA) has a wide range of applications in flavor and fragrance ingredients, green solvents, and pharmaceuticals. E-2HIBA has been synthesized by the batch transesterification of methyl 2-hydroxyisobutyrate with ethanol in the presence of titanium tetraethoxide (reaction conditions: 96 h, yield 97 %) and the esterification of 2-HIBA with an acid catalyst. The direct esterification of 2-HIBA with ethanol using an acid catalyst appears to be a commercially viable approach to produce E-2HIBA [1].
Chemical Properties
clear colorless liquid
Uses
Solvent for nitrocellulose and cellulose acetate; solvent mixture for cellulose ethers, organic synthesis, pharmaceuticals.
References
[1] Sripada, Sarada and James R. Kastner. “Continuous catalytic esterification using a solid acid activated carbon monolith: Comparison of granular and monolith forms with a commercial catalyst.” Chemical Engineering Journal 43 29 (2023): 0.
Ethyl 2-hydroxyisobutyrate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Aston Chemical | 13000000000 | sales@astonchem.com | United States | 1634 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 8318 | 58 |
| GLR Innovations | +91 9891111994 | info@glrgroup.in | India | 4535 | 58 |
View Lastest Price from Ethyl 2-hydroxyisobutyrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2023-07-27 | Ethyl 2-hydroxyisobutyrate
80-55-7
|
US $1.50 / g | 1g | 99.0% Min | 100 Tons | Shaanxi Didu New Materials Co. Ltd | |
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2020-03-16 | Ethyl 2-hydroxyisobutyrate
80-55-7
|
US $7.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-

- Ethyl 2-hydroxyisobutyrate
80-55-7
- US $1.50 / g
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd
-

- Ethyl 2-hydroxyisobutyrate
80-55-7
- US $7.00 / KG
- 99%
- Career Henan Chemical Co








