ChemicalBook >> CAS DataBase List >>(3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide
(3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide
![(3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide Structure](CAS/20180601/GIF/116855-81-3.gif)
- CAS No.
- 116855-81-3
- Chemical Name:
- (3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide
- Synonyms
- Iloprost Impurity 4;(3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide;Spiro[1,3-dioxane-2,2'(1'H)-pentalene]-4'-carboxamide, 5'-[[(1,1-dimethylethyl)dimethylsilyl]oxy]hexahydro-N-(2-hydroxy-1-phenylethyl)-5,5-dimethyl-, (3'aα,4'α(R*),5'β,6'aα)- (9CI)
- CBNumber:
- CB83920028
- Molecular Formula:
- C28H45NO5Si
- Molecular Weight:
- 503.75
- MDL Number:
- MOL File:
- 116855-81-3.mol
Last updated:2023-04-23 13:52:06
| Product description | Number | Pack Size | Price |
| (3a''S,4''R,5''R,6a''R)-5''-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2''(1''H)-pentalene]-4''-carboxamide | D473530 | 25mg | $365 |
(3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide Properties
| Boiling point | 614.7±55.0 °C(Predicted) |
|---|---|
| Density | 1.11±0.1 g/cm3(Predicted) |
| solubility | DCM, Ethyl Acetate |
| pka | 14.24±0.10(Predicted) |
| form | Powder |
| color | White |
(3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D473530 | (3a''S,4''R,5''R,6a''R)-5''-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2''(1''H)-pentalene]-4''-carboxamide | 116855-81-3 | 25mg | $365 | 2021-12-16 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| D473530 | 25mg | $365 | Buy |
(3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide Chemical Properties,Uses,Production
Uses
(3a''S,4''R,5''R,6a''R)-5''-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2''(1''H)-pentalene]-4''-carboxamide is an intermediate in the synthesis of Iloprost (I267300),a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, raynaud''s phenomenon and ischemia.
(3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
(3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44814 | 58 |
| Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 18162595016; 18162595016 | 3287908757@qq.com | China | 9119 | 58 |
| Supplier | Advantage |
|---|---|
| Energy Chemical | 58 |
| Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 58 |
(3aS,4R,5R,6aR)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2(1H)-pentalene]-4-carboxamide
Spiro[1,3-dioxane-2,2'(1'H)-pentalene]-4'-carboxamide, 5'-[[(1,1-dimethylethyl)dimethylsilyl]oxy]hexahydro-N-(2-hydroxy-1-phenylethyl)-5,5-dimethyl-, (3'aα,4'α(R*),5'β,6'aα)- (9CI)
Iloprost Impurity 4
116855-81-3
