4-FLUOROPHENYL METHYL SULFONE
- CAS No.
- 455-15-2
- Chemical Name:
- 4-FLUOROPHENYL METHYL SULFONE
- Synonyms
- 4-Fluorophenyl;4-FLUOROPHENYL METHY;Formula: FC6H4SO2CH3;Bicalutamide Impurity 30;4-FLUOROPHENYL METHYL SULFONE;Methyl 4-fluorophenyl sulfone;4-FLUOROPHENYL METHYL SULPHONE;Sulfone, p-fluorophenyl methyl;Methyl(4-fluorophenyl) sulfone;p-Fluorophenyl(methyl) sulfone
- CBNumber:
- CB8395595
- Molecular Formula:
- C7H7FO2S
- Molecular Weight:
- 174.19
- MDL Number:
- MFCD00039753
- MOL File:
- 455-15-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Fluorophenyl methyl sulfone 97% | 184330 | 5g | $44.8 |
| 4-Fluorophenyl Methyl Sulfone >98.0%(GC) | F0651 | 5g | $77 |
| 4-Fluorophenyl Methyl Sulfone >98.0%(GC) | F0651 | 25g | $302 |
| 4-FLUOROPHENYL METHYL SULFONE 95.00% | HCH0023865 | 5G | $791.18 |
| 4-Fluorophenyl Methyl Sulfone 98% | JK485417 | 25g | $309 |
| More product size | |||
| Melting point | 78-81 °C (lit.) |
|---|---|
| Boiling point | 95-97°C 7mm |
| Density | 1.2768 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Dichloromethane, Dimethyl Sulfoxide, Methanol |
| form | Adhering Crystalline Powder |
| color | Almost white |
| BRN | 2045674 |
| InChI | InChI=1S/C7H7FO2S/c1-11(9,10)7-4-2-6(8)3-5-7/h2-5H,1H3 |
| InChIKey | DPJHZJGAGIWXTD-UHFFFAOYSA-N |
| SMILES | C1(F)=CC=C(S(C)(=O)=O)C=C1 |
| CAS DataBase Reference | 455-15-2(CAS DataBase Reference) |
| FDA UNII | 8Z2TY4MZF4 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29309090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
4-FLUOROPHENYL METHYL SULFONE price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 184330 | 4-Fluorophenyl methyl sulfone 97% | 455-15-2 | 5g | $44.8 | 2023-06-20 | Buy |
| TCI Chemical | F0651 | 4-Fluorophenyl Methyl Sulfone >98.0%(GC) | 455-15-2 | 5g | $77 | 2026-03-19 | Buy |
| TCI Chemical | F0651 | 4-Fluorophenyl Methyl Sulfone >98.0%(GC) | 455-15-2 | 25g | $302 | 2026-03-19 | Buy |
| American Custom Chemicals Corporation | HCH0023865 | 4-FLUOROPHENYL METHYL SULFONE 95.00% | 455-15-2 | 5G | $791.18 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK485417 | 4-Fluorophenyl Methyl Sulfone 98% | 455-15-2 | 25g | $309 | 2021-12-16 | Buy |
4-FLUOROPHENYL METHYL SULFONE Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
4-Fluorophenyl methyl sulfone is used for preparation of substituted indazole amides as glucokinase activators.
Uses
4-Fluorophenyl methyl sulfone was used in the preparation of 4-(4′-trifluoromethoxyphenoxy)phenyl methyl sulfone.
Synthesis
A 500 mL flask was charged with 25.2 g of sodium sulfite, 100 mL of water, and 16.8 g of sodium bicarbonate. Heat to reflux and after all the solids are dissolved, add 21.0 g of 4-fluorobenzenesulfonyl chloride in batches and continue to heat to reflux for 4 hours. Cool to 40 C, 18.9 g of dimethyl sulfate was added dropwise from the dispensing funnel, with a dropwise acceleration to maintain the system temperature at 40~45 is appropriate. After dropping, the reaction was held for 2.5 h. After the methylation reaction was complete, the reaction was heated and refluxed for 1 h. The reaction was then heated and refluxed. Add 200mL of water, static cooling to room temperature, precipitated a large number of solids, filtered, washed with water, that is, p-fluorobenzenesulfone.
4-FLUOROPHENYL METHYL SULFONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Nanjing jinheyou Trading Co., Ltd. | 15705188088 | admin@jheyou.com | CHINA | 1268 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 10000 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15079 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
View Lastest Price from 4-FLUOROPHENYL METHYL SULFONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2022-02-22 | 4-Fluorophenyl methyl sulfone
455-15-2
|
US $0.00 / KG | 1KG | 97.3% | 100 tons | Honest Joy Holdings Limited | |
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2019-12-23 | 4-FLUOROPHENYL METHYL SULFONE
455-15-2
|
US $1.00 / KG | 1KG | 85.0-99.8% | 20ton | Career Henan Chemical Co | |
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2019-11-08 | 4-FLUOROPHENYL METHYL SULFONE
455-15-2
|
US $0.00 / g | 1g | 98%min | 20kg/month | Nanjing jinheyou Trading Co., Ltd. |
-

- 4-Fluorophenyl methyl sulfone
455-15-2
- US $0.00 / KG
- 97.3%
- Honest Joy Holdings Limited
-

- 4-FLUOROPHENYL METHYL SULFONE
455-15-2
- US $1.00 / KG
- 85.0-99.8%
- Career Henan Chemical Co
-

- 4-FLUOROPHENYL METHYL SULFONE
455-15-2
- US $0.00 / g
- 98%min
- Nanjing jinheyou Trading Co., Ltd.
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