ChemicalBook >> CAS DataBase List >>4-FLUOROPHENYL METHYL SULFONE

4-FLUOROPHENYL METHYL SULFONE

CAS No.
455-15-2
Chemical Name:
4-FLUOROPHENYL METHYL SULFONE
Synonyms
4-Fluorophenyl;4-FLUOROPHENYL METHY;Formula: FC6H4SO2CH3;Bicalutamide Impurity 30;4-FLUOROPHENYL METHYL SULFONE;Methyl 4-fluorophenyl sulfone;4-FLUOROPHENYL METHYL SULPHONE;Sulfone, p-fluorophenyl methyl;Methyl(4-fluorophenyl) sulfone;p-Fluorophenyl(methyl) sulfone
CBNumber:
CB8395595
Molecular Formula:
C7H7FO2S
Molecular Weight:
174.19
MDL Number:
MFCD00039753
MOL File:
455-15-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:00
Product description Number Pack Size Price
4-Fluorophenyl methyl sulfone 97% 184330 5g $44.8
4-Fluorophenyl Methyl Sulfone >98.0%(GC) F0651 5g $77
4-Fluorophenyl Methyl Sulfone >98.0%(GC) F0651 25g $302
4-FLUOROPHENYL METHYL SULFONE 95.00% HCH0023865 5G $791.18
4-Fluorophenyl Methyl Sulfone 98% JK485417 25g $309
More product size

4-FLUOROPHENYL METHYL SULFONE Properties

Melting point 78-81 °C (lit.)
Boiling point 95-97°C 7mm
Density 1.2768 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Dichloromethane, Dimethyl Sulfoxide, Methanol
form Adhering Crystalline Powder
color Almost white
BRN 2045674
InChI InChI=1S/C7H7FO2S/c1-11(9,10)7-4-2-6(8)3-5-7/h2-5H,1H3
InChIKey DPJHZJGAGIWXTD-UHFFFAOYSA-N
SMILES C1(F)=CC=C(S(C)(=O)=O)C=C1
CAS DataBase Reference 455-15-2(CAS DataBase Reference)
FDA UNII 8Z2TY4MZF4
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xn,Xi
Risk Statements  22
Safety Statements  24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29309090
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

4-FLUOROPHENYL METHYL SULFONE price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 184330 4-Fluorophenyl methyl sulfone 97% 455-15-2 5g $44.8 2023-06-20 Buy
TCI Chemical F0651 4-Fluorophenyl Methyl Sulfone >98.0%(GC) 455-15-2 5g $77 2026-03-19 Buy
TCI Chemical F0651 4-Fluorophenyl Methyl Sulfone >98.0%(GC) 455-15-2 25g $302 2026-03-19 Buy
American Custom Chemicals Corporation HCH0023865 4-FLUOROPHENYL METHYL SULFONE 95.00% 455-15-2 5G $791.18 2021-12-16 Buy
Frontier Specialty Chemicals JK485417 4-Fluorophenyl Methyl Sulfone 98% 455-15-2 25g $309 2021-12-16 Buy
Product number Packaging Price Buy
184330 5g $44.8 Buy
F0651 5g $77 Buy
F0651 25g $302 Buy
HCH0023865 5G $791.18 Buy
JK485417 25g $309 Buy

4-FLUOROPHENYL METHYL SULFONE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

4-Fluorophenyl methyl sulfone is used for preparation of substituted indazole amides as glucokinase activators.

Uses

4-Fluorophenyl methyl sulfone was used in the preparation of 4-(4′-trifluoromethoxyphenoxy)phenyl methyl sulfone.

Synthesis

A 500 mL flask was charged with 25.2  g of sodium sulfite, 100 mL of water, and 16.8 g of sodium bicarbonate. Heat to reflux and after all the solids are dissolved, add 21.0 g of 4-fluorobenzenesulfonyl chloride in batches and continue to heat to reflux for 4 hours. Cool to 40 C, 18.9 g of dimethyl sulfate was added dropwise from the dispensing funnel, with a dropwise acceleration to maintain the system temperature at 40~45  is appropriate. After dropping, the reaction was held for 2.5 h. After the methylation reaction was complete, the reaction was heated and refluxed for 1 h. The reaction was then heated and refluxed. Add 200mL of water, static cooling to room temperature, precipitated a large number of solids, filtered, washed with water, that is, p-fluorobenzenesulfone.

4-FLUOROPHENYL METHYL SULFONE Preparation Products And Raw materials

Global( 166)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29640 60
Nanjing jinheyou Trading Co., Ltd.
15705188088 admin@jheyou.com CHINA 1268 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9636 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 10000 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15079 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58

View Lastest Price from 4-FLUOROPHENYL METHYL SULFONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Fluorophenyl methyl sulfone pictures 2022-02-22 4-Fluorophenyl methyl sulfone
455-15-2
US $0.00 / KG 1KG 97.3% 100 tons Honest Joy Holdings Limited
4-FLUOROPHENYL METHYL SULFONE pictures 2019-12-23 4-FLUOROPHENYL METHYL SULFONE
455-15-2
US $1.00 / KG 1KG 85.0-99.8% 20ton Career Henan Chemical Co
4-FLUOROPHENYL METHYL SULFONE pictures 2019-11-08 4-FLUOROPHENYL METHYL SULFONE
455-15-2
US $0.00 / g 1g 98%min 20kg/month Nanjing jinheyou Trading Co., Ltd.
Sulfone, p-fluorophenyl methyl 4-FLUOROPHENYL METHYL SULPHONE 4-FLUOROPHENYL METHYL SULFONE 4-Fluorobenzenesulfinic Acid Methyl Este 4-Fluorophenyl 4-Fluorophenyl methyl sulphone 98% 4-Fluorophenylmethylsulphone98% Benzene,1-fluoro-4-(methylsulfonyl)- 4-Fluorobenzenesulfinic Acid Methyl Ester 1-FLUORO-4-(METHYLSULFONYL)BENZENE 1-fluoro-4-(methylsulphonyl)benzene 4-Fluorophenylmethylsulfone,97% Methyl 4-fluorophenyl sulfone Methyl(4-fluorophenyl) sulfone p-Fluorophenyl(methyl) sulfone 4-Fluorophenyl methyl sulfone,99% 1-Fluoro-4-Methanesulfonylbenzene Sulfone, p-Fluorophenyl Methyl Sulfone 4-Fluorophenyl Methyl sulfone, 98%+ Formula: FC6H4SO2CH3 4-FLUOROPHENYL METHY 4-FluorophenylMethylSulfone> Bicalutamide Impurity 30 4-Fluorophenyl methyl sulfone - [F3456] 455-15-2 FC6H4SO2CH3 Building Blocks Organic Building Blocks Sulfur Compounds Sulfones Aromatics Compounds Aromatics Sulfur & Selenium Compounds Organic Building Blocks Sulfones Sulfur Compounds