3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID
- CAS No.
- 328-80-3
- Chemical Name:
- 3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID
- Synonyms
- BUTTPARK 25\01-30;RARECHEM AL BO 1012;LABOTEST-BB LT00454389;3-CARBOXY-5-NITROBENZOTRIFLUORIDE;A,A,A-TRIFLUORO-5-NITRO-M-TOLUIC ACID;3-nitro-5-trifluoromethylbenzoic zoic;3-TRIFLUOROMETHYL-5-NITROBENZOIC ACID;5-(Trifluoromethyl)-3-nitrobenzoic acid;3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID;3-Nitro-5-(trifluoromethyl)benzoicacid97%
- CBNumber:
- CB8434625
- Molecular Formula:
- C8H4F3NO4
- Molecular Weight:
- 235.12
- MDL Number:
- MFCD00024509
- MOL File:
- 328-80-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID AldrichCPR | S600679 | 1 unit | $32.7 |
| 3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID Aldrich | S600679 | 250mg | $29.8 |
| 3-Trifluoromethyl-5-nitrobenzoic Acid | T1344 | 5g | $123 |
| 3-Trifluoromethyl-5-nitrobenzoic Acid | T1344 | 25g | $488 |
| 3-Nitro-5-(trifluoromethyl)benzoic acid | FN70457 | 25g | $150 |
| More product size | |||
| Melting point | 128 °C |
|---|---|
| Boiling point | 309.9±42.0 °C(Predicted) |
| Density | 1.596±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 3.05±0.10(Predicted) |
| color | White to Light yellow to Light orange |
| BRN | 2284651 |
| CAS DataBase Reference | 328-80-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-60-37 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S600679 | 3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID AldrichCPR | 328-80-3 | 1 unit | $32.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | S600679 | 3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID Aldrich | 328-80-3 | 250mg | $29.8 | 2024-03-01 | Buy |
| TCI Chemical | T1344 | 3-Trifluoromethyl-5-nitrobenzoic Acid | 328-80-3 | 5g | $123 | 2026-04-30 | Buy |
| TCI Chemical | T1344 | 3-Trifluoromethyl-5-nitrobenzoic Acid | 328-80-3 | 25g | $488 | 2026-04-30 | Buy |
| Biosynth | FN70457 | 3-Nitro-5-(trifluoromethyl)benzoic acid | 328-80-3 | 25g | $150 | 2026-06-04 | Buy |
3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID Chemical Properties,Uses,Production
Synthesis
454-92-2
328-80-3
The general procedure for synthesizing 3-nitro-5-(trifluoromethyl)benzoic acid from 3-trifluoromethylbenzoic acid is as follows: 1. 90% fuming nitric acid (210 mL) was slowly added to a solution of concentrated sulfuric acid (880 mL) of 3-trifluoromethylbenzoic acid (203.4 g) at 0 °C, and the addition process continued for 1 hour. 2. the reaction mixture was stirred at 35°C for 3 hours. 3. The reaction solution was slowly poured into ice (about 1 kg) to precipitate the product. 4. The precipitate was collected by filtration and washed with water (500 mL). 5. The precipitate was dissolved in ethyl acetate (500 mL) and the organic phase was washed with water. 6. After drying the organic phase, the solvent was evaporated under reduced pressure to give 3-nitro-5-(trifluoromethyl)benzoic acid (232.5 g, 92% yield) as a white powder. 1H-NMR (300MHz, CDCl3): δ 8.69 (1H, s), 8.74 (1H, s), 9.1 (1H, s).
References
[1] Patent: US2008/275085, 2008, A1. Location in patent: Page/Page column 45
[2] Journal of the American Chemical Society, 2017, vol. 139, # 43, p. 15308 - 15311
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 6, p. 2362 - 2380
[4] Angewandte Chemie - International Edition, 2017, vol. 56, # 8, p. 2059 - 2063
[5] Angew. Chem., 2017, vol. 129, # 8, p. 2091 - 2095,5
3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
View Lastest Price from 3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID
328-80-3
|
$1.00 | 1KG | 98% | 1kg,5kg,100kg | Career Henan Chemical Co |
-
- 3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID
328-80-3
- $1.00
- 98%
- Career Henan Chemical Co
328-80-3(3-NITRO-5-(TRIFLUOROMETHYL)BENZOIC ACID)Related Search:
1of4
