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5-Bromo-2-(trifluoromethyl)aniline

CAS No.
703-91-3
Chemical Name:
5-Bromo-2-(trifluoromethyl)aniline
Synonyms
5-Bromo-2-(trifluoro;2-AMino-4-broMobenzotrifluoride;5-BROMO-2-(TRIFLUOROMETHYL)ANILINE;5-BROMO-O-(TRIFLUOROMETHYL)ANILINE;2-Amino-4-bromobenzotrifluoride 98%;5-BroMo-2-trifluoroMethyl-phenylaMine;5-Bromo-2-(trifluoromethyl)benzenamine;Benzenamine, 5-bromo-2-(trifluoromethyl)-;5-Bromo-2-(trifluoromethyl)aniline, 5-Bromo-alpha,alpha,alpha-trifluoro-o-toluidine
CBNumber:
CB8439307
Molecular Formula:
C7H5BrF3N
Molecular Weight:
240.02
MDL Number:
MFCD00082853
MOL File:
703-91-3.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:46

5-Bromo-2-(trifluoromethyl)aniline Properties

Boiling point 84-86 °C(Press: 5 Torr)
Density 1.712 g/cm3(Temp: 25 °C)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 0.39±0.10(Predicted)
Appearance Pale purple to purple Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2921430090

5-Bromo-2-(trifluoromethyl)aniline price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B809945 5-Bromo-2-(Trifluoromethyl)aniline 703-91-3 50mg $60 2021-12-16 Buy
SynQuest Laboratories 3830-B-14 2-Amino-4-bromobenzotrifluoride 98% 703-91-3 5G $82 2021-12-16 Buy
Matrix Scientific 072933 5-Bromo-2-(trifluoromethyl)aniline 95+% 703-91-3 5g $156 2021-12-16 Buy
SynQuest Laboratories 3830-B-14 2-Amino-4-bromobenzotrifluoride 98% 703-91-3 25g $216 2021-12-16 Buy
Matrix Scientific 072933 5-Bromo-2-(trifluoromethyl)aniline 95+% 703-91-3 25g $489 2021-12-16 Buy
Product number Packaging Price Buy
B809945 50mg $60 Buy
3830-B-14 5G $82 Buy
072933 5g $156 Buy
3830-B-14 25g $216 Buy
072933 25g $489 Buy

5-Bromo-2-(trifluoromethyl)aniline Chemical Properties,Uses,Production

Synthesis

4-BROMO-2-NITRO-1-(TRIFLUOROMETHYL)BENZENE

251115-21-6

5-Bromo-2-(trifluoromethyl)aniline

703-91-3

General procedure for the synthesis of 5-bromo-2-(trifluoromethyl)aniline from 4-bromo-2-nitro-trifluoromethylbenzene: to a suspension of 4-bromo-2-nitro-1-(trifluoromethyl)benzene (4.0 g, 14.9 mmol) in ethanol (230 mL), THF (85 mL), and water (40 mL), ammonium chloride (1.0 g, 18.8 mmol) and iron powder (5.06 g, 90 mmol). The reaction mixture was heated at 80 °C for 1 h and the progress of the reaction was monitored by thin layer chromatography (TLC). After complete consumption of starting materials, the reaction mixture was filtered while hot. The filtrate was concentrated under reduced pressure and the crude product was dissolved in ethyl acetate (100 mL) and washed with water (3 x 50 mL). The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 5-bromo-2-(trifluoromethyl)aniline as a solid (3.2 g, 90% yield).

References

[1] Patent: WO2010/91310, 2010, A1. Location in patent: Page/Page column 100
[2] Patent: WO2014/149164, 2014, A1. Location in patent: Paragraph 00763; 00895

251115-21-6
703-91-3
Synthesis of 5-Bromo-2-(trifluoromethyl)aniline from 4-BROMO-2-NITRO-1-(TRIFLUOROMETHYL)BENZENE

5-Bromo-2-(trifluoromethyl)aniline Preparation Products And Raw materials

Global( 130)Suppliers
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View Lastest Price from 5-Bromo-2-(trifluoromethyl)aniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Bromo-2-(trifluoromethyl)aniline pictures 2022-02-21 5-Bromo-2-(trifluoromethyl)aniline
703-91-3
US $0.00 / KG 1KG 99.3% 100 tons Honest Joy Holdings Limited
5-Bromo-2-(trifluoromethyl)aniline pictures 2020-01-09 5-Bromo-2-(trifluoromethyl)aniline
703-91-3
US $1.00 / KG 1KG 99% 100KG Career Henan Chemical Co
5-BROMO-O-(TRIFLUOROMETHYL)ANILINE 5-BROMO-2-(TRIFLUOROMETHYL)ANILINE 2-Amino-4-bromobenzotrifluoride 98% 5-Bromo-2-(trifluoromethyl)aniline, 5-Bromo-alpha,alpha,alpha-trifluoro-o-toluidine 2-AMino-4-broMobenzotrifluoride 5-Bromo-2-(trifluoro 5-BroMo-2-trifluoroMethyl-phenylaMine Benzenamine, 5-bromo-2-(trifluoromethyl)- 5-Bromo-2-(trifluoromethyl)benzenamine 703-91-3 454-79-1