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ChemicalBook >> CAS DataBase List >>N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide

N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide

N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide Structure
N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide structure
CAS No.
1190277-80-5
Chemical Name:
N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide
Synonyms
MKI-1;MKI-1, 10 mM in DMSO;MKI-1/MASTL Kinase Inhibitor-1;N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide;N-1H-Benzimidazol-2-yl-3-(1H-pyrrol-1-yl)benzamide;Benzamide, N-1H-benzimidazol-2-yl-3-(1H-pyrrol-1-yl)-;N-(1H-Benzo[d]imidazol-2-yl)-3-(1H-pyrrol-1-yl)benzamide
CBNumber:
CB84458467
Molecular Formula:
C18H14N4O
Molecular Weight:
302.33
MDL Number:
MFCD13758448
MOL File:
1190277-80-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
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N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide Properties

Density 1.31±0.1 g/cm3(Predicted)
pka 10.56±0.10(Predicted)
form Solid
color Off-white to light yellow

N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth QXB27780 N-1H-Benzimidazol-2-yl-3-(1H-pyrrol-1-yl)benzamide 1190277-80-5 25mg $1237.25 2026-06-04 Buy
Biosynth QXB27780 N-1H-Benzimidazol-2-yl-3-(1H-pyrrol-1-yl)benzamide 1190277-80-5 50mg $1721 2026-06-04 Buy
ChemScene CS-0139947 MKI-1 98.13% 1190277-80-5 5mg $195 2026-06-04 Buy
ChemScene CS-0139947 MKI-1 98.13% 1190277-80-5 10mg $292 2026-06-04 Buy
ChemScene CS-0139947 MKI-1 98.13% 1190277-80-5 25mg $468 2026-06-04 Buy
Product number Packaging Price Buy
QXB27780 25mg $1237.25 Buy
QXB27780 50mg $1721 Buy
CS-0139947 5mg $195 Buy
CS-0139947 10mg $292 Buy
CS-0139947 25mg $468 Buy

N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide Chemical Properties, Uses, Production

Uses

MKI-1, an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like) with an IC50 of 9.9 μM, exerts antitumor and radiosensitizer activities through PP2A activation in breast cancer[1].

in vivo

MKI-1 (50 mg/kg, ip, twice a week) reduces tumor growth and enhances the radiosensitivity of BT549 xenograft model in response to 6 Gy irradiation compared with the control group, with no notable changes in body weight, suggesting the absence of gross toxicity in the treated mice[1].

Animal Model:Five-week-old female BALB/c nude mice (BT549 cells)[1].
Dosage:50 mg/kg.
Administration:Twice per week by intraperitoneal (i.p.) injection.
Result:Reduced tumor growth.

References

[1] Ah-Young Kim, et al. MKI-1, a Novel Small-Molecule Inhibitor of MASTL, Exerts Antitumor and Radiosensitizer Activities Through PP2A Activation in Breast cancer. Front Oncol. 2020 Sep 29;10:571601. DOI:10.3389/fonc.2020.571601

N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide Suppliers

Global Suppliers ( 27)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2994 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9780 55
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 sales@linyuepharm.com China 5731 55
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 5000 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 18100677375 sales@szzxbio.com China 1129 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
MQ (shanghai) Pharmaceuticals Co., Ltd. 55
TargetMol Chemicals Inc. 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58
Suzhou Zhixin Biotechnology Co., Ltd. 58

View Latest Price from N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MKI-1 pictures 2026-07-14 MKI-1
1190277-80-5
 $61.00-222.00 99.81% 10g TargetMol Chemicals Inc.
  • MKI-1 pictures
  • MKI-1
    1190277-80-5
  • $61.00-222.00
  • 99.81%
  • TargetMol Chemicals Inc.

N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide Spectrum

N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide(1190277-80-5)1HNMR

1190277-80-5 (N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide) Related Search:

N-(3-Cyano-4,5,6,7-tetrahydro-2-benzothienyl)-3-phenylpropanamide Anti-Aging Compound Library Anti-cancer compound library 2-Oxazolidinone, 3-[1-amino-6-[[4-(1-amino-1-ethylpropyl)-2-pyridinyl]amino]-2,7-naphthyridin-3-yl]- N6-[4-(3-Amino-3-pentyl)-2-pyridyl]-3-(1-methyl-1H-1,2,3-triazol-5-yl)-2,7-naphthyridine-1,6-diamine
MASTL-IN-3

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N-(1H-benzimidazol-2-yl)-3-pyrrol-1-ylbenzamide MKI-1 Benzamide, N-1H-benzimidazol-2-yl-3-(1H-pyrrol-1-yl)- MKI-1/MASTL Kinase Inhibitor-1 N-(1H-Benzo[d]imidazol-2-yl)-3-(1H-pyrrol-1-yl)benzamide MKI-1, 10 mM in DMSO N-1H-Benzimidazol-2-yl-3-(1H-pyrrol-1-yl)benzamide 1190277-80-5