C30(-hydroxy) Ceramide (d18:1/30:0)
- CAS No.
- 457100-08-2
- Chemical Name:
- C30(-hydroxy) Ceramide (d18:1/30:0)
- Synonyms
- C30(ω-hydroxy) Ceramide (d18:1/30:0);C30(-hydroxy) Ceramide (d18:1/30:0);30-Hydroxytriacontanoyl-D-erythro-sphingosine;30-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-triacontanamide;Triacontanamide, 30-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
- CBNumber:
- CB84666343
- Molecular Formula:
- C48H95NO4
- Molecular Weight:
- 750.27
- MDL Number:
- MOL File:
- 457100-08-2.mol
- MSDS File:
- SDS
C30(-hydroxy) Ceramide (d18:1/30:0) price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22688 | C30 (ω-hydroxy) Ceramide (d18:1/30:0) ≥98% | 457100-08-2 | 5mg | $630 | 2026-04-30 | Buy |
| ChemScene | CS-0063670 | C30(ω-hydroxy) Ceramide d18:1/30:0 99.46% | 457100-08-2 | 1mg | $485 | 2026-06-04 | Buy |
| aablocks | AA01EPNV | C30(ω-hydroxy) Ceramide (d18:1/30:0) ≥98% | 457100-08-2 | 5mg | $699 | 2026-05-30 | Buy |
| AK Scientific | 2275EL | N-[(2S,3R,4E)-1,3-Dihydroxyoctadec-4-en-2-yl]-30-hydroxytriacontanamide | 457100-08-2 | 5mg | $1072 | 2021-12-16 | Buy |
C30(-hydroxy) Ceramide (d18:1/30:0) Chemical Properties, Uses, Production
Description
C30(ω-hydroxy) Ceramide is a bioactive sphingolipid found in the stratum corneum layer of mammalian epidermis. C30(ω-hydroxy) Ceramide is vital to skin barrier functions and has a role in maturation of epidermis cells of the spermatozoa/testes. C30(ω-hydroxy) Ceramide deficiency causes defective skin-water permeability barrier function and neonatal lethality in elongation of very long chain fatty acids-4 (ELOVL4) deficient mice. [Matreya, LLC. Catalog No. 2080]
Uses
C30(ω-hydroxy) Ceramide (d18:1/30:0), a sphingolipid, is an epidermis-specifically vital component of the water barrier in mammalian skin. C30(ω-hydroxy) Ceramide (d18:1/30:0) is expressed in epidermal keratinocytes and male germ cells during their differentiation and maturation. C30(ω-hydroxy) Ceramide (d18:1/30:0) deficiency in the epiderm of Elovl4 deletion or mutation mice[1][2].
Definition
ChEBI: N-(omega-hydroxytriacontanoyl)sphingosine is an N-acylsphingosine that has omega-hydroxytriacontanoyl as the acyl group. A bioactive sphingolipid found in the stratum corneum layer of mammalian epidermis. It is a N-acylsphingosine, an omega-hydroxy-ultra-long chain fatty acylceramide and a N-(omega-hydroxy-ultra-long chain fatty acyl)sphingosine. It is functionally related to an omega-hydroxytriacontanoic acid.
References
[1] Jennemann R, et al. Integrity and barrier function of the epidermis critically depend on glucosylceramide synthesis. J Biol Chem. 2007 Feb 2;282(5):3083-94. DOI:10.1074/jbc.M610304200
[2] Sandhoff R. Very long chain sphingolipids: tissue expression, function and synthesis. FEBS Lett. 2010 May 3;584(9):1907-13. DOI:10.1016/j.febslet.2009.12.032
C30(-hydroxy) Ceramide (d18:1/30:0) Preparation Products And Raw materials
Raw materials
Preparation Products
C30(-hydroxy) Ceramide (d18:1/30:0) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1978 | 58 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9170 | 60 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 18019219489 18901678489 | tech@zzbioco.com | China | 12062 | 58 |
