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(2-Fluorobenzyl)methylamine

(2-Fluorobenzyl)methylamine Structure
(2-Fluorobenzyl)methylamine structure
CAS No.
399-30-4
Chemical Name:
(2-Fluorobenzyl)methylamine
Synonyms
1-(2-FLUOROPHENYL)-N-METHYLMETHANAMINE;(2-FLUOROBENZYL)METH;(2-Fluorobenzyl)methylamine;(2-fluorobenZzyl)methylamine;2-FLUORO-N-METHYLBENZYLAMINE;N-Methyl-2-fluorobenzylaMine;N-Methyl-o-fluorobenzylamine;(2-Fluorobenzyl)Methyla E 95%;(2-Fluorobenzyl)methylamine95%;(2-FLUOROBENZYL)METHYLAMINE 95%
CBNumber:
CB8473549
Molecular Formula:
C8H10FN
Molecular Weight:
139.17
MDL Number:
MFCD04629633
MOL File:
399-30-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:45
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(2-Fluorobenzyl)methylamine Properties

Melting point 139-140 °C
Boiling point 73 °C/12 mmHg (lit.)
Density 1.047 g/mL at 25 °C (lit.)
refractive index n20/D 1.5010(lit.)
Flash point 155 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 9.05±0.10(Predicted)
form Liquid
color Colorless to tan
Water Solubility Slightly soluble in water.
Sensitive Air Sensitive
InChI 1S/C8H10FN/c1-10-6-7-4-2-3-5-8(7)9/h2-5,10H,6H2,1H3
InChIKey AHIHZCXUWGORQO-UHFFFAOYSA-N
SMILES CNCc1ccccc1F
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  26-36/37
WGK Germany  3
HS Code  2921490090
Storage Class 10 - Combustible liquids
Hazard Classifications Aquatic Chronic 3
Eye Irrit. 2
Skin Irrit. 2
NFPA 704
2
2 0

(2-Fluorobenzyl)methylamine price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 631094 2-Fluoro-N-methylbenzylamine 97% 399-30-4 1g $65.1 2023-06-20 Buy
Sigma-Aldrich 631094 2-Fluoro-N-methylbenzylamine 97% 399-30-4 5g $162 2022-05-15 Buy
Apolloscientific PC201248 (2-Fluorobenzyl)methylamine 98% 399-30-4 5g $21 2026-06-04 Buy
Apolloscientific PC201248 (2-Fluorobenzyl)methylamine 98% 399-30-4 25g $59 2026-06-04 Buy
Apolloscientific PC201248 (2-Fluorobenzyl)methylamine 98% 399-30-4 100g $232 2026-06-04 Buy
Product number Packaging Price Buy
631094 1g $65.1 Buy
631094 5g $162 Buy
PC201248 5g $21 Buy
PC201248 25g $59 Buy
PC201248 100g $232 Buy

(2-Fluorobenzyl)methylamine Chemical Properties, Uses, Production

Uses

It is used as a pharmaceutical intermediate.

Uses

Reactant for:

  • Preparation of biologically and pharmacologically active molecules

Synthesis

Methanesulfonamide, 1,1,1-trifluoro-N-[(2-fluorophenyl)methyl]-N-methyl-

1159505-77-7

(2-FLUOROBENZYL)METHYLAMINE

399-30-4

Example 4 Synthesis of N-methyl-2-fluorobenzylamine: to a stirred solution of compound 16 (135.6 mg, 0.5 mmol, 1.0 eq.) in anhydrous THF (5 mL) was slowly added LiAlH4 (38 mg, 1.0 mmol, 2.0 eq.) at 0 °C. The reaction mixture was heated to reflux and stirred for 10 hours. Upon completion of the reaction, it was cooled to room temperature and the reaction was carefully quenched with water and subsequently extracted with ether (10 mL x 3). The target product N-methyl-2-fluorobenzylamine was isolated and purified by acid/base extraction using 2N HCl and 2N NaOH. Finally, the solvent was evaporated under reduced pressure (15 torr) to give the colorless oily product N-methyl-2-fluorobenzylamine (60 mg, 86% yield).

References

[1] Journal of the American Chemical Society,
[2] Journal of the American Chemical Society, 2009, vol. 131, p. 7520 - 7521
[3] Patent: US2012/59179, 2012, A1. Location in patent: Page/Page column 17

(2-Fluorobenzyl)methylamine Preparation Products And Raw materials

Raw materials

Methylamine Hydrogen bromide Phosphorus tribromide 2-Fluorobenzyl alcohol Methanesulfonamide, 1,1,1-trifluoro-N-[(2-fluorophenyl)methyl]-N-methyl-
Lithium Aluminum Hydride Tetrahydrofuran

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Preparation Products

(2-Fluorobenzyl)methylamine Suppliers

Global Suppliers ( 108)
Supplier Tel Email Country ProdList Advantage
Creasyn Finechem(Tianjin) Co., Ltd. 022-83946278 13820372920 sales@creasyn.com China 968 68
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Shenyang Yuancheng Pharmaceutical Technology Co., Ltd. 024-31298370 15040047923 yuanchengchem@163.com China 252 52
Shanghai Litong Chemical Technology Co.,Ltd. 13598610367 0373-7129549 2468833170@qq.com China 932 58
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Supplier Advantage
Creasyn Finechem(Tianjin) Co., Ltd. 68
Alfa Aesar 84
Energy Chemical 61
Accela ChemBio Co.,Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Shandong Xiya Chemical Co., Ltd 57
Syntechem Co.,Ltd 57
Shenyang Yuancheng Pharmaceutical Technology Co., Ltd. 52
Shanghai Litong Chemical Technology Co.,Ltd. 58
Shanghai Topbiochem Technology Co., Ltd 58

View Latest Price from (2-Fluorobenzyl)methylamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(2-FLUOROBENZYL)METHYLAMINE pictures 2019-07-12 (2-FLUOROBENZYL)METHYLAMINE
399-30-4
 $1.00 1KG 99% 25kg Career Henan Chemical Co

(2-Fluorobenzyl)methylamine Spectrum

(2-FLUOROBENZYL)METHYLAMINE(399-30-4)1HNMR

399-30-4 ((2-Fluorobenzyl)methylamine) Related Search:

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2-FLUORO-N-METHYLBENZYLAMINE (2-Fluorobenzyl)methylamine95% (2-FLUOROBENZYL)METHYLAMINE 95% (2-fluorobenZzyl)methylamine (2-Fluorobenzyl)Methyla E 95% (2-FLUOROBENZYL)METH N-Methyl-o-fluorobenzylamine N-Methyl-2-fluorobenzylaMine Benzenemethanamine, 2-fluoro-N-methyl- (2-Fluorobenzyl)Methylamine,>98% 2-Fluoro-N-methylbenzylamine 1-(2-FLUOROPHENYL)-N-METHYLMETHANAMINE (2-Fluorobenzyl)methylamine 399-30-4 Building Blocks Amines C8 Nitrogen Compounds Organic Building Blocks Amines C8 Nitrogen Compounds