BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
- CAS No.
- 23749-58-8
- Chemical Name:
- BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
- Synonyms
- luminor2;luminogren;luminophor2;Yellow 2GF;Fluorescein T;AHR agonist 3;7H-Benzimidazo[2;yellow-green490rt;Solvent Yellow 184;LABOTEST-BB LT00007121
- CBNumber:
- CB8476272
- Molecular Formula:
- C18H10N2O
- Molecular Weight:
- 270.28
- MDL Number:
- MFCD00056826
- MOL File:
- 23749-58-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| BENZO(DE)BENZO(4,5)IMIDAZO(2,1-A)ISOQUINOLIN-7-ONE AldrichCPR | S51021 | 1 unit | $152 |
| BENZO(DE)BENZO(4,5)IMIDAZO(2,1-A)ISOQUINOLIN-7-ONE Aldrich | S51021 | 10mg | $139 |
| 7H-Benzimidazo[2,1-a]benz[de]isoquinolin-7-one min. 98.0 % | B6583 | 5G | $113 |
| 7H-Benzimidazo[2,1-a]benz[de]isoquinolin-7-one min. 98.0 % | B6583 | 25G | $339 |
| 7H-Benzimidazo[2,1-a]benz[de]isoquinolin-7-one 96% | AA00BDSK | 25g | $343 |
| More product size | |||
| Melting point | 189 °C |
|---|---|
| Boiling point | 613.6±38.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| pka | 2.05±0.20(Predicted) |
| form | powder |
| color | Bright yellow |
| InChI | InChI=1S/C18H10N2O/c21-18-13-8-4-6-11-5-3-7-12(16(11)13)17-19-14-9-1-2-10-15(14)20(17)18/h1-10H |
| InChIKey | NZBSAAMEZYOGBA-UHFFFAOYSA-N |
| SMILES | C12=NC3=CC=CC=C3N1C(=O)C1=CC=CC3=CC=CC2=C13 |
| EWG's Food Scores | 1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P312 | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S51021 | BENZO(DE)BENZO(4,5)IMIDAZO(2,1-A)ISOQUINOLIN-7-ONE AldrichCPR | 23749-58-8 | 1 unit | $152 | 2026-04-30 | Buy |
| Sigma-Aldrich | S51021 | BENZO(DE)BENZO(4,5)IMIDAZO(2,1-A)ISOQUINOLIN-7-ONE Aldrich | 23749-58-8 | 10mg | $139 | 2024-03-01 | Buy |
| TCI Chemical | B6583 | 7H-Benzimidazo[2,1-a]benz[de]isoquinolin-7-one min. 98.0 % | 23749-58-8 | 5G | $113 | 2026-04-30 | Buy |
| TCI Chemical | B6583 | 7H-Benzimidazo[2,1-a]benz[de]isoquinolin-7-one min. 98.0 % | 23749-58-8 | 25G | $339 | 2026-04-30 | Buy |
| aablocks | AA00BDSK | 7H-Benzimidazo[2,1-a]benz[de]isoquinolin-7-one 96% | 23749-58-8 | 25g | $343 | 2026-05-28 | Buy |
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Chemical Properties,Uses,Production
Uses
AHR agonist 3 is an aryl hydrocarbon receptor (AhR) agonist, that can induces cell cycle arrest or apoptosis via activation of tumor-suppressive transcriptional programs. AHR agonist 3 inhibits triple-negative breast cancer (TNBC) stem cell growth via AhR while exhibits minimal cytotoxicity against normal human primary cells and can be used for cancer research[1].
Application
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE is a derivative of benzimidazo[2,1-a]benz[d,e]isoquinolion-7-one fluorophore, which is known to enter the cells and localize into the acidic organelles[2].
Properties and Applications
|
TEST ITEMS |
SPECIFICATION |
|
APPEARANCE |
YELLOW POWDER |
|
SHADE |
GREENISH |
|
HEAT RESISTANCE |
260 °C min |
|
LIGHT FASTNESS |
5-6 |
|
ACID RESISTANCE |
5 |
|
ALKALI RESISTANCE |
5 |
|
WATER RESISTANCE |
5 |
|
DENSITY |
1.20 g/cm 3 |
|
RESIDUE ON 80 MESH |
5.0% max |
|
WATER SOLUBLE |
1.0% max |
|
VOLATITE 105 °C |
1.0% max |
|
TINTING STRENGTH |
100-105 % |
|
WEIGHT METAL TOTAL |
50ppm max |
References
[1] Elson DJ, et.al. Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline. ACS Pharmacol Transl Sci. 2023 Jun 7;6(7):1028-1042. DOI:10.1021/acsptsci.2c00253
[2] Faggi, E., Luis, S. V., & Alfonso, I. (2019). Sensing, Transport and Other Potential Biomedical Applications of Pseudopeptides. Current Medicinal Chemistry, 26 21<, 4065–4097. https://doi.org/10.2174/0929867325666180301091040
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hinova Pharma | +86-18190684138 +86-18190684138 | xhchen00241@hinovapharma.com | China | 61 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9542 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hebei Zhanyao Biotechnology Co. Ltd | 15369953316 +8615369953316 | admin@zhanyaobio.com | China | 2123 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15073 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9950 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
View Lastest Price from BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2021-10-19 | Solvent Yellow 184
23749-58-8
|
$10.00 | 1Kg/Bag | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd | |
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2021-10-11 | Solvent Yellow 184
23749-58-8
|
$10.00 | 1KG | 99% | 20 tons | Hebei Zhanyao Biotechnology Co. Ltd |
-

- Solvent Yellow 184
23749-58-8
- $10.00
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
-

- Solvent Yellow 184
23749-58-8
- $10.00
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
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