Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>trans-nerolidol

trans-nerolidol

trans-nerolidol Structure
trans-nerolidol structure
CAS No.
40716-66-3
Chemical Name:
trans-nerolidol
Synonyms
1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (E)-;TRANS-NEROLIDOL;(E)-Nerolidol;E-Nerolidol;(6E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol;trans-Nerolidal solution;trans-Form;Nerolidol (E);Trans-neroliol;Einecs 255-053-4
CBNumber:
CB8497598
Molecular Formula:
C15H26O
Molecular Weight:
222.37
MDL Number:
MFCD00008911
MOL File:
40716-66-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
Product description Number Pack Size Price
TRANS-NEROLIDOL AldrichCPR R751405 1 unit $152
trans-Nerolidol analyticalstandard 18143 100mg $88.4
trans-Nerolidol primary pharmaceutical reference standard 04610590 50mg $435
trans-Nerolidal solution certified reference material, 2000?μg/mL in methanol, ampule of 1?mL CRM40742 1mL $95.2
trans-Nerolidol 25778 50mg $27
More product size
Request For Quotation

trans-nerolidol Properties

Boiling point 145-146 °C12 mm Hg(lit.)
Density 0.876 g/mL at 25 °C(lit.)
refractive index n20/D 1.479(lit.)
Flash point 230 °F
storage temp. -20°C
solubility DMF: miscible,DMSO: miscible,Ethanol: miscible,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka 14.40±0.29(Predicted)
form Liquid
color Colorless to light yellow
Odor at 100.00 %. floral green citrus woody waxy
Odor Type floral
Merck 13,6501
JECFA Number 1646
BRN 5731231
Stability Light Sensitive
Major Application food and beverages
Cosmetics Ingredients Functions PERFUMING
InChI 1S/C15H26O/c1-6-15(5,16)12-8-11-14(4)10-7-9-13(2)3/h6,9,11,16H,1,7-8,10,12H2,2-5H3/b14-11+
InChIKey FQTLCLSUCSAZDY-SDNWHVSQSA-N
SMILES C\C(C)=C/CC\C(C)=C\CCC(C)(O)C=C
LogP 5.316 (est)
EWG's Food Scores 1
FDA UNII FG5V0N8P2H
NIST Chemistry Reference 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (e)-(40716-66-3)
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H317-H319-H410
Precautionary statements  P261-P264-P273-P280-P302+P352-P305+P351+P338
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  1
F  10-23
Storage Class 10 - Combustible liquids
Hazard Classifications Aquatic Acute 1
Aquatic Chronic 1
Eye Irrit. 2
Skin Sens. 1B
Toxicity Both the acute oral LD50 in rats and the acute dermal LD50 in rabbits exceeded 5 g/kg (Russell. 1973).
NFPA 704
0
2 0

trans-nerolidol price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R751405 TRANS-NEROLIDOL AldrichCPR 40716-66-3 1 unit $152 2026-03-19 Buy
Sigma-Aldrich 18143 trans-Nerolidol analyticalstandard 40716-66-3 100mg $88.4 2026-03-19 Buy
Sigma-Aldrich 04610590 trans-Nerolidol primary pharmaceutical reference standard 40716-66-3 50mg $435 2026-03-19 Buy
Sigma-Aldrich CRM40742 trans-Nerolidal solution certified reference material, 2000?μg/mL in methanol, ampule of 1?mL 40716-66-3 1mL $95.2 2022-05-15 Buy
Cayman Chemical 25778 trans-Nerolidol 40716-66-3 50mg $27 2024-03-01 Buy
Product number Packaging Price Buy
R751405 1 unit $152 Buy
18143 100mg $88.4 Buy
04610590 50mg $435 Buy
CRM40742 1mL $95.2 Buy
25778 50mg $27 Buy

trans-nerolidol Chemical Properties,Uses,Production

Description

trans-Nerolidol is a sesquiterpene that has been found in various plants, including C. sativa, and has diverse biological activities, including antimicrobial, antioxidant, anticancer, and insecticidal properties. In a disc assay, trans-nerolidol inhibits the growth of S. aureus, B. subtilis, E. coli, and S. cerevisiae with zones of inhibition measuring 10, 9, 10, and 4 mm, respectively. It reduces viability of CaCo-2 adenocarcinoma cells with an IC50 value of 28.7 mg/L and reduces production of reactive oxygen species (ROS). trans-Nerolidol is insecticidal against A. aegypti larvae with a 24-hour LC50 value of 9 mg/L.

Occurrence

Reported to be found in cabreuva oil, oil of neroli, balsam Peru, ylang ylang and many others (Gildemeister & Hoffman, 1959).

Uses

Nerolidol (cas# 40716-66-3) is a terpene standard found in cannabis.

Preparation

By isolation from a suitable essential oil or by chemical synthesis.

Definition

ChEBI: Nerolidol is a farnesane sesquiterpenoid that is dodeca-1,6,10-triene which carries methyl groups at positions 3, 7 and 11 and a hydroxy group at position 3. It is a natural product that is present in various flowers and plants with a floral odor. Chemically, it exists in two geometric isomers, trans and cis forms. It is widely used in cosmetics (e.g. shampoos and perfumes), in non-cosmetic products (e.g. detergents and cleansers) and also as a food flavoring agent. It has a role as a flavouring agent, a cosmetic, a pheromone, a neuroprotective agent, an antifungal agent, an anti-inflammatory agent, an antihypertensive agent, an antioxidant, a volatile oil component, an insect attractant and a herbicide. It is a farnesane sesquiterpenoid, a tertiary allylic alcohol and a volatile organic compound.

References

[1] LORENZO NISSEN . Characterization and antimicrobial activity of essential oils of industrial hemp varieties (Cannabis sativa L.)[J]. Fitoterapia, 2010, 81 5: Pages 413-419. DOI: 10.1016/j.fitote.2009.11.010
[2] H D SKALTSA. Composition and antimicrobial activity of the essential oil of Scutellaria albida ssp. albida from Greece.[J]. Planta medica, 2000, 66 7: 672-674. DOI: 10.1055/s-2000-8650
[3] MARTIN AMBRO. The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells.[J]. Molecules, 2015, 20 8: 15343-15358. DOI: 10.3390/molecules200815343
[4] J. CHANTRAINE. Insecticidal activity of essential oils on Aedes aegypti larvae[J]. Phytotherapy Research, 1998, 64 3. DOI: 10.1002/(sici)1099-1573(199808)12:5<350::aid-ptr311>3.0.co;2-7

trans-nerolidol synthesis

3796-70-1
1826-67-1
40716-66-3
Synthesis of trans-nerolidol from Geranylacetone and Vinylmagnesium bromide

trans-nerolidol Preparation Products And Raw materials

Raw materials

5-Hepten-1-yne, 6-methyl- Diphosphoric acid, mono[(2Z,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl] ester CIS-TRANS-FARNESOL GERANYL BROMIDE Geranylacetone
Linalool 6,10-Dimethyl-5,9-undecadien-2-one

1of2

Preparation Products

Teprenone Impurity 20 (E)-BETA-FARNESENE (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienal

trans-nerolidol Suppliers

Global( 233)Suppliers
Supplier Tel Email Country ProdList Advantage
Ningbo Banco Chemical Technology Co., Ltd.
+86-15827200700 sales@bancochemical.com China 487 58
Hebei Zhuanglai Chemical Trading Co Ltd 		+86-16264648883 niki@zlchemi.com China 7245 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29821 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		+86 18953170293 sales@sdzschem.com China 1497 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
Kindchem(Nanjing)Co.,Ltd 		+86-025-025-85281586 +8618651653755 sales@kindchem.cn China 1226 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9541 58
Baoji Guokang Healthchem co.,ltd 		+8615604608665 15604608665 dominicguo@gk-bio.com CHINA 9414 58
Supplier Advantage
Ningbo Banco Chemical Technology Co., Ltd.
58
Hebei Zhuanglai Chemical Trading Co Ltd 		58
career henan chemical co 		58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		58
Chengdu Biopurify Phytochemicals Ltd. 		58
Kindchem(Nanjing)Co.,Ltd 		58
TargetMol Chemicals Inc. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Finetech Industry Limited 		58
Baoji Guokang Healthchem co.,ltd 		58

View Lastest Price from trans-nerolidol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
trans-Nerolidol pictures 2026-04-22 trans-Nerolidol
40716-66-3
 US $64.00-40.00 / mg 99.01% 10g TargetMol Chemicals Inc.
Nerolidol pictures 2025-05-23 Nerolidol
40716-66-3
 US $50.00 / kg 1kg 99 5000 Hebei Zhuanglai Chemical Trading Co Ltd
Nerolidol pictures 2019-07-06 Nerolidol
40716-66-3
 US $1.00 / kg 1g 99% 100KG Career Henan Chemical Co
  • trans-Nerolidol pictures
  • trans-Nerolidol
    40716-66-3
  • US $64.00-40.00 / mg
  • 99.01%
  • TargetMol Chemicals Inc.
  • Nerolidol pictures
  • Nerolidol
    40716-66-3
  • US $50.00 / kg
  • 99
  • Hebei Zhuanglai Chemical Trading Co Ltd
  • Nerolidol pictures
  • Nerolidol
    40716-66-3
  • US $1.00 / kg
  • 99%
  • Career Henan Chemical Co

trans-nerolidol Spectrum

trans-nerolidol(40716-66-3)1HNMR

40716-66-3(trans-nerolidol)Related Search:

Methyl cyclopentenolone Teprenone Impurity 20 LINOLENIC ACID ETHYL ESTER Allyl methacrylate CHLOROPHOSPHONAZO III
Diniconazole Triethylenetetramine METHYLCYCLOPENTADIENE DIMER 6-Methyl-5-hepten-2-one Mesityl oxide
Nerolidol rich-d-t-Prallethrin Nerolidol, acetate CIS-NEROLIDOL,NEROLIDOL, CIS-,(S)-cis-nerolido CIS-NEROLIDOL WITH GC,CIS-NEROLIDOL,NEROLIDOL, CIS-,NEROLIDOL, cis-(SG),(Z)-nerolidol,(6Z)-3,7,11-trimethyl-1,6,10-dodecatrien-3-ol,cis-nerolidol
rich_d_transallethrin trans-nerolidol NEROLIDOL NATURAL

1of4

Teprenone Impurity 19 trans-Nerolidal solution (6E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol Trans-(E)-Nerolidol 3-Hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene (E)-3,7,11-trimethyldodeca-1,6,10-trien-3-ol nerolidol,(6E)-3,7,11-trimethyl-1,6,10-dodecatrien-3-ol,peruviol,trans-nerolidol 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (6E)- TRANS-NEROLIDOL WITH GC (E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol, trans-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol (E)-3,7,11-Trimethyldodeca-1,6,10-triene-3-ol [R,Z,(-)]-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol Einecs 255-053-4 Nerolidol (E) Nerolidol trans-form trans-Nerolidol,(E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol, trans-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol trans-Form Teprenone Impurity 19 (trans-Nerolidol) Teprenone Impurity 5 （trans-Nerolidol） Teprenone Impurity 2 (trans-Nerolidol) TRANS-NEROLIDOL trans-Nerolidol (±)-trans-Nerolidol (+/-)-trans-Nerolidol 95% Terpene Mixture 2 100 μg/mL in Methanol Terpene Mixture 2 2500 μg/mL in Hexane Terpene Standard A, 15-1436, 1000 mg/L Trans-Nerolidol (>90%) Trans-neroliol 1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (E)- (6E)-3,7,11-Trimethyldodeca-1,6,10-trien-3-ol (E)-Nerolidol E-Nerolidol 40716-66-3