CPEB4 antibody
- CAS No.
- Chemical Name:
- CPEB4 antibody
- Synonyms
- CPEB4 antibody
- CBNumber:
- CB85619182
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
CPEB4 antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb419646 | CPEB4 Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb182707 | CPEB4 antibody Affinity purified by Protein A | 100μg | $421.6 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb182707 | CPEB4 antibody Affinity purified by Protein A | 200μg | $673.2 | 2021-12-16 | Buy |
CPEB4 antibody Chemical Properties, Uses, Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Background
Cytoplasmic polyadenylation element-binding proteins are a family of sequence-specific RNA-binding proteins that bind to the CPE, a uridine-rich sequence element within the mRNA 3’ UTR, to regulate mRNA translation. The CPEB family consists of four members in vertebrates: CPEB1, CPEB2, CPEB3, and CPEB4. All four paralogs share sequence similarities in their carboxy-terminal RNA-binding domains, but vary in the sequence of their amino-terminal regulatory domains. CPEB4 has specifically been linked to autism spectrum disorder, where it has been found to bind to the mRNA transcripts of most high-confidence ASD risk genes. Moreover, young idiopathic ASD individuals show decreased CPEB4 protein levels in the brain, and consequently decreased protein levels of multiple ASD risk gene transcripts compared to controls. CPEB4 is also abnormally expressed in a large number of cancers and often correlates with poor prognosis, including glioblastoma/glioma, head and neck squamous cell carcinoma, non-small cell lung cancer, colon cancer, and breast cancer, among others.
References
[1] Afroz, T. et al. (2014) Genes Dev 28, 1498-1514.
[2] Tsai, L.Y. et al. (2016) PLoS One 11, e0155025.
[3] Parras, A. et al. (2018) Nature 560, 441-446.
[4] Wang, H.X. et al. (2018) Clin Neurol Neurosurg 169, 92-97.
[5] Zhijun, L. et al. (2017) Tumour Biol 39, 1010428317694538.
[6] Zeng, M. et al. (2018) Oncol Lett 15, 3226-3232.
[7] Hu, J. et al. (2018) Cell Biol Int 42, 1484-1491.
[8] Cortés-Guiral, D. et al. (2017) Pathol Res Pract 213, 639-642.
[9] Lu, R. et al. (2017) Biochem Biophys Res Commun 489, 135-141.
CPEB4 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
CPEB4 antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
