IL12B Antibody
- CAS No.
- Chemical Name:
- IL12B Antibody
- Synonyms
- IL12B Antibody;Rabbit Polyclonal IL12B Antibody
- CBNumber:
- CB85646751
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
IL12B Antibody Chemical Properties, Uses, Production
Applications
IL12B antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000.
Immunogen
Anti-human IL12B mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human IL12B amino acids 23-328 purified from E. coli.
Background
IL12B is a subunit of interleukin 12 which is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40kDa cytokine receptor like subunit encoded by the IL12B gene, and a 35kDa subunit encoded by IL12A. The IL12B cytokine is expressed by activated macrophages which serve as an important inducer of Th1 cells development. The IL12B cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of the IL12B gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of the IL12B cytokine in the pathogenesis of the disease. The promoter polymorphism of the IL12B gene has been reported to be linked to the severity of atopic and non-atopic asthma in children.
IL12B Antibody Preparation Products And Raw materials
Raw materials
Preparation Products
IL12B Antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Novus Biologicals | -- | orders@novusbio.com | China | 6433 | 58 |
| CUSABIO TECHNOLOGY LLC | -- | cusabio@163.com | China | 6066 | 58 |
| NSJ Bioreagents | -- | NSJBioname@qq.com | China | 6941 | 58 |
| Enzo Biochem Inc | -- | Enzoname@qq.com | China | 6173 | 58 |
| Biosynth Ltd | -- | sales@biosynth.com | China | 6218 | 58 |
| Abmart Inc | -- | market@ab-mart.com | China | 6917 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | -- | sales@biosynth.com | China | 6032 | 58 |
| Adooq Bioscience LLC | -- | sales@adooq.cn | China | 6208 | 58 |
| ProSpec Tany TechnoGene Ltd | -- | info@prospecbio.com | China | 6874 | 58 |
| Rockland Immunochemicals Inc | -- | antibodies-onlinename@qq.com | China | 6808 | 58 |
| Supplier | Advantage |
|---|---|
| Novus Biologicals | 58 |
| CUSABIO TECHNOLOGY LLC | 58 |
| NSJ Bioreagents | 58 |
| Enzo Biochem Inc | 58 |
| Biosynth Ltd | 58 |
| Abmart Inc | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 58 |
| Adooq Bioscience LLC | 58 |
| ProSpec Tany TechnoGene Ltd | 58 |
| Rockland Immunochemicals Inc | 58 |
