PRDX2 Antibody
- CAS No.
- Chemical Name:
- PRDX2 Antibody
- Synonyms
- PRDX2 Antibody;Rabbit Polyclonal PRDX2 Antibody
- CBNumber:
- CB85675900
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
PRDX2 Antibody Chemical Properties,Uses,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat
Background
Peroxiredoxin 2 is a ubiquitously expressed thioredoxin peroxidase. The enzyme catalyzes the reduction of hydrogen peroxide and organic hydroperoxides via the thioredoxin system. An antioxidant, PRDX2 neutralizes endogenous reactive oxygen species and regulates cytokine-induced peroxide levels for normal cell function. Research studies have shown that PRDX2 plays important roles in inflammation, cancer, and natural killer cell activation. During cancer progression, PRDX2 is upregulated and protects cancer cells from oxidative stress-induced apoptosis. In inflammatory diseases such as infection, myocardial infarction, and ischemia, PRDX2 not only protects cells from oxidative stress-induced death, but is also released into extracellular space to trigger local inflammation and to activate NK cells for innate immune response.
References
[1] Peskin, A.V. et al. (2007) J Biol Chem 282, 11885-92.
[2] Poole, L.B. et al. (2011) Curr Protoc Toxicol Chapter 7, Unit7.9.
[3] Ishii, T. et al. (2012) J Clin Biochem Nutr 50, 91-105.
[4] Stresing, V. et al. (2013) Oncogene 32, 724-35.
[5] Lu, W. et al. (2014) Mol Cell Biochem 387, 261-70.
[6] Knoops, B. et al. (2016) Mol Cells 39, 60-4.
[7] Jin, X. et al. (2017) Sci Rep 7, 6970.
PRDX2 Antibody Preparation Products And Raw materials
Raw materials
Preparation Products
PRDX2 Antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Hubei Serenity BioSolutions Co., Ltd. | 027-19371278702 18008634902 | 19384116026@163.com | China | 3008 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
| Hubei Serenity BioSolutions Co., Ltd. | 58 |
