Src Inhibitor 3
- CAS No.
- 2380027-49-4
- Chemical Name:
- Src Inhibitor 3
- Synonyms
- Src Inhibitor 3;Src Inhibitor 3, 10 mM in DMSO;Src,Src Inhibitor3,inhibit,Src Inhibitor 3,Src Inhibitor-3,Inhibitor;N-[3-chloro-4-[(6-methoxypyrazolo[1,5-a]pyridine-3-carbonyl)amino]phenyl]-1-[1-(3-cyano-3-methylbutanoyl)piperidin-4-yl]-5-fluoroindazole-3-carboxamide;1H-Indazole-3-carboxamide, N-[3-chloro-4-[[(6-methoxypyrazolo[1,5-a]pyridin-3-yl)carbonyl]amino]phenyl]-1-[1-(3-cyano-3-methyl-1-oxobutyl)-4-piperidinyl]-5-fluoro-
- CBNumber:
- CB85838992
- Molecular Formula:
- C34H32ClFN8O4
- Molecular Weight:
- 671.12
- MDL Number:
- MFCD32263443
- MOL File:
- 2380027-49-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Src Inhibitor 3 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FVD02749 | Src inhibitor 3 | 2380027-49-4 | 10mg | $1047.8 | 2026-06-04 | Buy |
| Biosynth | FVD02749 | Src inhibitor 3 | 2380027-49-4 | 25mg | $1708.75 | 2026-06-04 | Buy |
| Biosynth | FVD02749 | Src inhibitor 3 | 2380027-49-4 | 50mg | $2733.5 | 2026-06-04 | Buy |
| ChemScene | CS-0106066 | CSK-IN-1 98.04% | 2380027-49-4 | 1mg | $206 | 2026-06-04 | Buy |
| ChemScene | CS-0106066 | CSK-IN-1 98.04% | 2380027-49-4 | 5mg | $433 | 2026-06-04 | Buy |
Src Inhibitor 3 Chemical Properties, Uses, Production
Uses
CSK-IN-1 (compound 13) is a potent, orally active c-terminal Src kinase (CSK) with IC50 values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively. CSK-IN-1 shows the ability to increase T cell proliferation induced by T cell receptor signaling[1].
in vivo
CSK-IN-1 (compound 13) reduces inhibitory LCK phosphorylation in vivo upon oral dosing and shows the ability to enhance T cell activation in response to antigen stimulation[1].
References
[1] O'Malley DP, et al. Discovery of Pyridazinone and Pyrazolo[1,5-a]pyridine Inhibitors of C-Terminal Src Kinase. ACS Med Chem Lett. 2019 Sep 25;10(10):1486-1491. DOI:10.1021/acsmedchemlett.9b00354
Src Inhibitor 3 Preparation Products And Raw materials
Raw materials
Preparation Products
Src Inhibitor 3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4860 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4058 | 58 |
| Wuhan chuang he chemical co. LTD | 15907120073 | 1261789306@qq.com | China | 1358 | 58 |
| Hefei fuya biotechnology co. LTD | 18096409024 | sales02@foreversyn.com | China | 1934 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Nantong Hi-Future Biotechnology Co., Ltd | +86-0513; 18051384581 | sales@chemhifuture.com | China | 3075 | 58 |
| Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd. | 15720605021 | zhang_lei@jsnchem.com | China | 1881 | 58 |
