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2-BROMO-5-HYDROXYMETHYLTHIAZOLE

2-BROMO-5-HYDROXYMETHYLTHIAZOLE Structure
2-BROMO-5-HYDROXYMETHYLTHIAZOLE structure
CAS No.
687636-93-7
Chemical Name:
2-BROMO-5-HYDROXYMETHYLTHIAZOLE
Synonyms
2-BROMOTHIAZOLE-5-METHANOL;CAS:687636-93-7;RARECHEM AL BD 1435;2-Bromo-5-thiazolemethanol;5-Thiazolemethanol, 2-bromo-;2-Bromo-5-hydromethylthiazole;(2-bromothiazol-5-yl)methanol;(2-bromo-5-thiazolyl)methanol;2-BROMO-5-HYDROXYMETHYLTHIAZOLE;(2-BROMO-1,3-THIAZOL-5-YL)METHANOL
CBNumber:
CB8669339
Molecular Formula:
C4H4BrNOS
Molecular Weight:
194.05
MDL Number:
MFCD04115733
MOL File:
687636-93-7.mol
Last updated:2026-05-28 03:49:10
Product description Number Pack Size Price
2-Bromo-5-hydroxymethylthiazole SYX00336 1g $191
2-Bromo-5-hydroxymethylthiazole 97% AS50076 1g $93
2-Bromo-5-hydroxymethylthiazole 97% AS50076 5g $283
2-Bromo-5-hydroxymethylthiazole 97% AS50076 25g $848
2-Bromo-5-(hydroxymethyl)-1,3-thiazole 95% OR5599 1g $117
Request For Quotation

2-BROMO-5-HYDROXYMETHYLTHIAZOLE Properties

Melting point 46-48
Boiling point 288.3±15.0 °C(Predicted)
Density 1.899±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form powder
pka 13.23±0.10(Predicted)
color Light yellow
InChI 1S/C4H4BrNOS/c5-4-6-1-3(2-7)8-4/h1,7H,2H2
InChIKey DWNJWSPPORNJGV-UHFFFAOYSA-N
SMILES BrC1=NC=C(CO)S1
CAS DataBase Reference 687636-93-7(CAS DataBase Reference)
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  22
WGK Germany  WGK 3
Hazard Note  Irritant
HS Code  2934100090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

2-BROMO-5-HYDROXYMETHYLTHIAZOLE price More Price(76)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SYX00336 2-Bromo-5-hydroxymethylthiazole 687636-93-7 1g $191 2026-04-30 Buy
Activate Scientific AS50076 2-Bromo-5-hydroxymethylthiazole 97% 687636-93-7 1g $93 2026-06-04 Buy
Activate Scientific AS50076 2-Bromo-5-hydroxymethylthiazole 97% 687636-93-7 5g $283 2026-06-04 Buy
Activate Scientific AS50076 2-Bromo-5-hydroxymethylthiazole 97% 687636-93-7 25g $848 2026-06-04 Buy
Apolloscientific OR5599 2-Bromo-5-(hydroxymethyl)-1,3-thiazole 95% 687636-93-7 1g $117 2026-06-04 Buy
Product number Packaging Price Buy
SYX00336 1g $191 Buy
AS50076 1g $93 Buy
AS50076 5g $283 Buy
AS50076 25g $848 Buy
OR5599 1g $117 Buy

2-BROMO-5-HYDROXYMETHYLTHIAZOLE Chemical Properties,Uses,Production

Synthesis

2-Bromo-5-fomylthiazole

464192-28-7

2-BROMO-5-HYDROXYMETHYLTHIAZOLE

687636-93-7

General procedure for the synthesis of 2-bromothiazole-5-methanol from 2-bromo-5-formylthiazole: 2-bromothiazole-5-formaldehyde (3.00 g, 15.62 mmol) was mixed with methanol (50 mL). The mixture was cooled to 0 °C under nitrogen protection and sodium borohydride (0.591 g, 15.62 mmol) was added in batches. The reaction was stirred at this temperature for 2 hours. Subsequently, the reaction system was slowly warmed to room temperature and stirring was continued for 2 hours. After completion of the reaction, the solvent was removed by concentration under reduced pressure. To the residue, saturated aqueous ammonium chloride solution was added, and the pH was adjusted to about 6 with 1 M aqueous hydrochloric acid, and then adjusted to about 10 with 1 M aqueous sodium hydroxide. the mixture was extracted with ethyl acetate, and the organic layer was washed sequentially with saturated brine, dried with anhydrous sodium sulfate, filtered, and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography eluting with a gradient of ethyl acetate/hexane (10% to 25%) to give 2-bromothiazole-5-methanol as a light yellow oil. Mass spectrum (DCI+) m/z 194,196 (M+H)+.

References

[1] Patent: WO2012/87833, 2012, A1. Location in patent: Page/Page column 125-126
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 25, p. 6303 - 6306
[3] Patent: WO2004/37818, 2004, A1. Location in patent: Page 69 - 70
[4] Patent: WO2007/75749, 2007, A2. Location in patent: Page/Page column 25; 37-39
[5] Patent: WO2009/77990, 2009, A1. Location in patent: Page/Page column 92

2-BROMO-5-HYDROXYMETHYLTHIAZOLE Preparation Products And Raw materials

Raw materials

2-Bromo-5-fomylthiazole Ethyl 2-bromothiazole-5-carboxylate Sodium hydroxide Hydrochloric acid

Preparation Products

2-Bromo-5-fomylthiazole

2-BROMO-5-HYDROXYMETHYLTHIAZOLE Suppliers

Global( 136)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10403 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10236 58
HONG KONG IPURE BIOLOGY CO.,LIMITED 		86 18062405514 18062405514 ada@ipurechemical.com CHINA 3461 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
Supplier Advantage
Shenzhen Nexconn Pharmatechs Ltd 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Hubei Ipure Biology Co., Ltd 		58
HONG KONG IPURE BIOLOGY CO.,LIMITED 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58

View Lastest Price from 2-BROMO-5-HYDROXYMETHYLTHIAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-BROMO-5-HYDROXYMETHYLTHIAZOLE pictures 2020-01-09 2-BROMO-5-HYDROXYMETHYLTHIAZOLE
687636-93-7
 $1.00 1KG 95-99% 1ton Career Henan Chemical Co

2-BROMO-5-HYDROXYMETHYLTHIAZOLE Spectrum

2-BROMO-5-HYDROXYMETHYLTHIAZOLE(687636-93-7)1HNMR

687636-93-7(2-BROMO-5-HYDROXYMETHYLTHIAZOLE)Related Search:

2-BROMO-5-(METHYLSULFONYL)PYRIDINE 2-BROMO-5-CHLOROBENZONITRILE 2-BROMO-5-HYDROXYMETHYLTHIAZOLE 2-Bromo-4-thiazolecarboxylic acid ETHYL 2-BROMO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE
Ethyl 2-bromothiazole-5-carboxylate 2-BROMO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLIC ACID Methyl 2-bromothiazole-5-carboxylate 2-Bromothiazole 5-Hydroxymethylthiazole
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2-Bromo-5-hydromethylthiazole (2-Bromo-1,3-thiazol-5-yl)methanol 97% 2-Bromo-5-(hydroxymethyl)-1,3-thiazole (2-bromo-5-thiazolyl)methanol (2-bromothiazol-5-yl)methanol 2-Bromo-5-(hydroxymethyl)-1,3-thiazole 97% RARECHEM AL BD 1435 (2-BROMO-1,3-THIAZOL-5-YL)METHANOL 2-BROMO-5-HYDROXYMETHYLTHIAZOLE 2-Bromo-5-(hydroxymethyl)-1,3-thiazole97% 2-Bromo-5-thiazolemethanol 5-Thiazolemethanol, 2-bromo- CAS:687636-93-7 2-BROMOTHIAZOLE-5-METHANOL 687636-93-7 blocks Bromides Thiazoles Building Blocks Thiazole