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1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE structure

CAS No.: 17364-16-8

Chemical Name:: 1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Synonyms: LYSO-PC;1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOCHOLINE;16:0 LYSO PC;1-hexadecanoyl-sn-glycero-3-phosphocholine;LYSO-PPC;Palmitoyl Lyso-phosphocholine;1-Pal PC;P-LYSO-PC;Choline Impurity 1;LysoFos Choline 16

CBNumber:: CB8672575

Molecular Formula:: C24H50NO7P

Molecular Weight:: 495.63

MDL Number:: MFCD00036904

MOL File:: 17364-16-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 03:50:23

Product description	Number	Pack Size	Price
1-Palmitoyl-sn-glycero-3-phosphocholine synthetic, ≥99%	L5254	25mg	$148
1-Palmitoyl-sn-glycero-3-phosphocholine synthetic, ≥99%	L5254	1g	$2440
1-Palmitoyl-sn-glycero-3-phosphocholine	P2694	250MG	$235
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC ≥98%(9:1mixtureof1-acyland2-acyl)	10172	25mg	$50
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC ≥98%(9:1mixtureof1-acyland2-acyl)	10172	50mg	$95
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1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Properties

Melting point	253 °C
storage temp.	-20°C
solubility	Chloroform (Slightly), Methanol (Slightly, Heated)
form	Solid
color	White to Off-White
biological source	synthetic
optical activity	Consistent with structure
BRN	5385682
InChI	InChI=1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1
InChIKey	ASWBNKHCZGQVJV-HSZRJFAPSA-N
SMILES	O(C(=O)CCCCCCCCCCCCCCC)C[C@H](COP(OCC[N+](C)(C)C)([O-])=O)O
UNSPSC Code	51191904
NACRES	NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS08

Signal word

Danger

Hazard statements

H302-H315-H319-H331-H336-H351-H361d-H372-H412

Precautionary statements

P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313

PPE

Eyeshields, Gloves, type N95 (US)

WGK Germany

10-21

HS Code

2923.20.2000

Storage Class

11 - Combustible Solids

NFPA 704

	3
3		0

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE price More Price(67)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	L5254	1-Palmitoyl-sn-glycero-3-phosphocholine synthetic, ≥99%	17364-16-8	25mg	$148	2026-04-30	Buy
Sigma-Aldrich	L5254	1-Palmitoyl-sn-glycero-3-phosphocholine synthetic, ≥99%	17364-16-8	1g	$2440	2026-04-30	Buy
TCI Chemical	P2694	1-Palmitoyl-sn-glycero-3-phosphocholine	17364-16-8	250MG	$235	2026-04-30	Buy
Cayman Chemical	10172	1-Palmitoyl-2-hydroxy-sn-glycero-3-PC ≥98%(9:1mixtureof1-acyland2-acyl)	17364-16-8	25mg	$50	2026-04-30	Buy
Cayman Chemical	10172	1-Palmitoyl-2-hydroxy-sn-glycero-3-PC ≥98%(9:1mixtureof1-acyland2-acyl)	17364-16-8	50mg	$95	2026-04-30	Buy

Product number	Packaging	Price	Buy
L5254	25mg	$148	Buy
L5254	1g	$2440	Buy
P2694	250MG	$235	Buy
10172	25mg	$50	Buy
10172	50mg	$95	Buy

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Uses,Production

Description

1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A₂ (PLA₂) hydrolysis of phosphatidylcholine. It increases the production of reactive oxygen species (ROS) and decreases superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS) protein levels and phosphorylation of ERK1/2 in human umbilical vein endothelial cells (HUVECs) when used at a concentration of 125 μM. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC potentiates the secretion of IL-6, IL-1β, IL-12, and TNF-α in LPS-stimulated M1 macrophages, but has no effect on CD163, CD206, CD36, or IL-10 in LPS-stimulated M2 macrophages when used at concentrations of 0.3 and 1.0 μM. It increases TGF-β1 production and enhances Foxp3 protein levels in T_reg cells in isolated human peripheral blood when used at a concentration of 10 μM. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC enhances neutrophil function, bacterial clearance, and survival in mouse models of sepsis when administered at a dose of 10 mg/kg.

Chemical Properties

White Solid

Uses

A lipid biomarker for stable and unstable heart disease.

Uses

16:0 Lyso PC has been used to reveal the central role of the adipocyte inflammasome in homocysteine-induced insulin resistance. It has also been used for lipid extraction and mass spectrometry analysis.

Definition

ChEBI: 1-hexadecanoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine 16:0 in which a hexadecanoyl (palmitoyl) group is attached to the glycero moiety at position 1. It has a role as a mouse metabolite. It is a lysophosphatidylcholine 16:0 and a 1-O-acyl-sn-glycero-3-phosphocholine.

Biochem/physiol Actions

1-Palmitoyl-sn-glycero-3-phosphocholine may be used as a substrate to identify, differentiate and characterize lysophosphocholine acyl transferases.

References

[1] JESúS BALSINDE Edward A D Michelle V Winstead. Phospholipase A2 regulation of arachidonic acid mobilization[J]. FEBS Letters, 2002, 531 1: Pages 2-6. DOI: 10.1016/s0014-5793(02)03413-0
[2] SHINKYU CHOI. Superoxide generated by lysophosphatidylcholine induces endothelial nitric oxide synthase downregulation in human endothelial cells.[J]. Cellular Physiology and Biochemistry, 2010, 25 2-3: 233-240. DOI: 10.1159/000276557
[3] XIAOFEI QIN Luosha Z Chunguang Qiu. Lysophosphatidylcholine perpetuates macrophage polarization toward classically activated phenotype in inflammation[J]. Cellular immunology, 2014, 289 1: Pages 185-190. DOI: 10.1016/j.cellimm.2014.04.010
[4] HITOSHI HASEGAWA . Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-β production[J]. Biochemical and biophysical research communications, 2011, 415 3: Pages 526-531. DOI: 10.1016/j.bbrc.2011.10.119
[5] JI-JING YAN. Therapeutic effects of lysophosphatidylcholine in experimental sepsis[J]. Nature Medicine, 2004, 10 2: 161-167. DOI: 10.1038/nm989

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers

Global( 206)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Moxin Chemicals	+86-17320513646 +8617320513646	anna@molcoo.com	China	10000	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16512	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	14026	58
Shochem(Shanghai) Co.,Ltd	86-21-50800795	info@shochem.com	CHINA	288	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
Creative Enzymes	1-516-855-7709	info@creative-enzymes.com	United States	8748	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10236	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30224	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	86 18062405514 18062405514	ada@ipurechemical.com	CHINA	3461	58

Supplier	Advantage
Moxin Chemicals	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Shochem(Shanghai) Co.,Ltd	58
BOC Sciences	58
Creative Enzymes	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58
Career Henan Chemica Co	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	58

View Lastest Price from 1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-02	1-Palmitoyl-sn-glycero-3-phosphocholine 17364-16-8	$2.20-8.80	1kg	99%min	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-05-11	1-Palmitoyl-sn-glycero-3-phosphocholine 17364-16-8	$39.00-98.00		99.85%	10g	TargetMol Chemicals Inc.
2025-12-16	Phosphonylcholine Impurity 17364-16-8		10mg	99%+ HPLC	1000	Moxin Chemicals

1-Palmitoyl-sn-glycero-3-phosphocholine
17364-16-8
$2.20-8.80
99%min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

1-Palmitoyl-sn-glycero-3-phosphocholine
17364-16-8
$39.00-98.00
99.85%
TargetMol Chemicals Inc.

Phosphonylcholine Impurity
17364-16-8
99%+ HPLC
Moxin Chemicals

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Spectrum

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(17364-16-8)¹HNMR

17364-16-8(1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE)Related Search:

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1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, HEPTADECANOYL 1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1of4

P-LYSO-PC L-ALPHA-PALMITOYL-LYSOPHOSPHATIDYLCHOLINE L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, PALMITOYL L-GAMMA-PALMITOYL-ALPHA-LYSOLECITHIN LYSOLECITHIN, PALMITOYL LYSO-PPC 3-SN-LYSOPHOSPHATIDYLCHOLINE, 1-PALMITOYL 1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-PALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 1-PALMITOYL-2-LYSO-SN-GLYCERO-3-PHOSPHOCHOLINE 1-HEXADECANOYL-SN-GLYCEROL-3-PHOSPHORYLCHOLINE L-A-LYSOPHOSPHATIDYLCHOLINE, PALMITOYL 1-hexadecanoyl-sn-glycero-3-phosphocholine 1-Hexadecanoyl-sn-glycero-3-phosphocholine, 3-sn-Lysophosphatidylcholine, 1-palmitoyl, L-α-Palmitoyl-lysophosphatidylcholine, L-γ-Palmitoyl-α-lysolecithin, Lysolecithin, palmitoyl [O-[1-O-Hexadecanoyl-L-glycero-3-phospho]choline]anion 1-Hexadecylglycero-3-phosphocholine 1-Palmitoyl-2-lyso-sn-glycero-3-phosphatidylcholine 1-Palmitoylglycero-3-phosphocholine Palmitoyllysophosphatidylcholine L-α-Palmitoyl-lysophosphatidylcholine L-γ-Palmitoyl-α-lysolecithin, Lysolecithin Palmitoyl Lyso-phosphocholine 1-PalMitoyl-2-hydroxy-sn-glycero-3-phosphocholine (P-lysoPC, LPC) (7R)-3,5,9-4,7-Dihydroxy-N,N,N-triMethyl-10-oxotrioxa-4-phosphapentacosan-1-aMiniuM 4-Oxide Inner Salt 1-Hexadecanoyllysolecithin 1-O-PalMitoyl-2-lyso-sn-glycero-3-p L-g-PalMitoyl-a-lysolecithin 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, sodiuM salt (DSPG) L-γ-Palmitoyl-α-lysolecithin L-A-LYSOPHOSPHATIDYLCHOLINE, PALMITO 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC 1-Palmitoyl-sn-glycero-3-phosphocholine(P-LysoPC) Palmitoyl phosphocholine Choline Impurity 1 (R)-2-Hydroxy-3-(palmitoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate 3,5,9-Trioxa-4-phosphapentacosan-1-aminium,4,7-dihydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide, (7R)- 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC MaxSpec Standard LysoFos Choline 16 1-Pal PC P-LySOPC 1-Hexadecanyl-sn-propythritol phosphatidylcholine 1-Palmitoyl-sn-glycero-3-phosphocholine 1-Hexadecanoyl-sn-propythritol phosphatidylcholine P-lyso-PC (short route) 1-Palmitoyl-sn-glycero-3-phosphocholine【L5254】 1-Hexadecanoyl-SN-glycerol-phosphocholine Lecithin Impurity 49 L-Palmitoyllysolecithin P-LysoPC (16:0 Lyso PC) 16:0 LYSO PC 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOCHOLINE LYSO-PC 16:0 Lyso PC (1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine) 17364-16-8 C24H50NO7P C24H510NO7P Lipids Glycerophosphonocholines Glycerides