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1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Structure
1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE structure
CAS No.
17364-16-8
Chemical Name:
1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonyms
LYSO-PC;1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOCHOLINE;16:0 LYSO PC;1-hexadecanoyl-sn-glycero-3-phosphocholine;LYSO-PPC;Palmitoyl Lyso-phosphocholine;1-Pal PC;P-LYSO-PC;Choline Impurity 1;LysoFos Choline 16
CBNumber:
CB8672575
Molecular Formula:
C24H50NO7P
Molecular Weight:
495.63
MDL Number:
MFCD00036904
MOL File:
17364-16-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
Request For Quotation

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Properties

Melting point 253 °C
storage temp. -20°C
solubility Chloroform (Slightly), Methanol (Slightly, Heated)
form Solid
color White to Off-White
biological source synthetic
optical activity Consistent with structure
BRN 5385682
InChI InChI=1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1
InChIKey ASWBNKHCZGQVJV-HSZRJFAPSA-N
SMILES O(C(=O)CCCCCCCCCCCCCCC)C[C@H](COP(OCC[N+](C)(C)C)([O-])=O)O
UNSPSC Code 51191904
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
Signal word  Danger
Hazard statements  H302-H315-H319-H331-H336-H351-H361d-H372-H412
Precautionary statements  P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  3
F  10-21
HS Code  2923.20.2000
Storage Class 11 - Combustible Solids
NFPA 704
3
3 0

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L5254 1-Palmitoyl-sn-glycero-3-phosphocholine synthetic, ≥99% 17364-16-8 25mg $148 2026-04-30 Buy
Sigma-Aldrich L5254 1-Palmitoyl-sn-glycero-3-phosphocholine synthetic, ≥99% 17364-16-8 1g $2440 2026-04-30 Buy
TCI Chemical P2694 1-Palmitoyl-sn-glycero-3-phosphocholine 17364-16-8 250MG $235 2026-04-30 Buy
Cayman Chemical 10172 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC ≥98%(9:1mixtureof1-acyland2-acyl) 17364-16-8 25mg $50 2026-04-30 Buy
Cayman Chemical 10172 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC ≥98%(9:1mixtureof1-acyland2-acyl) 17364-16-8 50mg $95 2026-04-30 Buy
Product number Packaging Price Buy
L5254 25mg $148 Buy
L5254 1g $2440 Buy
P2694 250MG $235 Buy
10172 25mg $50 Buy
10172 50mg $95 Buy

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Uses,Production

Description

1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine. It increases the production of reactive oxygen species (ROS) and decreases superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS) protein levels and phosphorylation of ERK1/2 in human umbilical vein endothelial cells (HUVECs) when used at a concentration of 125 μM. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC potentiates the secretion of IL-6, IL-1β, IL-12, and TNF-α in LPS-stimulated M1 macrophages, but has no effect on CD163, CD206, CD36, or IL-10 in LPS-stimulated M2 macrophages when used at concentrations of 0.3 and 1.0 μM. It increases TGF-β1 production and enhances Foxp3 protein levels in Treg cells in isolated human peripheral blood when used at a concentration of 10 μM. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC enhances neutrophil function, bacterial clearance, and survival in mouse models of sepsis when administered at a dose of 10 mg/kg.

Chemical Properties

White Solid

Uses

A lipid biomarker for stable and unstable heart disease.

Uses

16:0 Lyso PC has been used to reveal the central role of the adipocyte inflammasome in homocysteine-induced insulin resistance. It has also been used for lipid extraction and mass spectrometry analysis.

Definition

ChEBI: 1-hexadecanoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine 16:0 in which a hexadecanoyl (palmitoyl) group is attached to the glycero moiety at position 1. It has a role as a mouse metabolite. It is a lysophosphatidylcholine 16:0 and a 1-O-acyl-sn-glycero-3-phosphocholine.

Biochem/physiol Actions

1-Palmitoyl-sn-glycero-3-phosphocholine may be used as a substrate to identify, differentiate and characterize lysophosphocholine acyl transferases.

References

[1] JESúS BALSINDE  Edward A D  Michelle V Winstead. Phospholipase A2 regulation of arachidonic acid mobilization[J]. FEBS Letters, 2002, 531 1: Pages 2-6. DOI: 10.1016/s0014-5793(02)03413-0
[2] SHINKYU CHOI. Superoxide generated by lysophosphatidylcholine induces endothelial nitric oxide synthase downregulation in human endothelial cells.[J]. Cellular Physiology and Biochemistry, 2010, 25 2-3: 233-240. DOI: 10.1159/000276557
[3] XIAOFEI QIN  Luosha Z  Chunguang Qiu. Lysophosphatidylcholine perpetuates macrophage polarization toward classically activated phenotype in inflammation[J]. Cellular immunology, 2014, 289 1: Pages 185-190. DOI: 10.1016/j.cellimm.2014.04.010
[4] HITOSHI HASEGAWA . Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-β production[J]. Biochemical and biophysical research communications, 2011, 415 3: Pages 526-531. DOI: 10.1016/j.bbrc.2011.10.119
[5] JI-JING YAN. Therapeutic effects of lysophosphatidylcholine in experimental sepsis[J]. Nature Medicine, 2004, 10 2: 161-167. DOI: 10.1038/nm989

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers

Global( 208)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Jindi Pharmaceutical Technology Co., Ltd 13564401937 wangtao@jindipharma.com.cn China 27 58
Suzhou Highfine Biotech Co., Ltd 0512-69209928 18796809688 zhouyingxiang@highfine.com China 1846 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@163.com China 280 58
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Supplier Advantage
Shanghai Jindi Pharmaceutical Technology Co., Ltd 58
Suzhou Highfine Biotech Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61
Adamas Reagent, Ltd. 59
Chemsky（shanghai）International Co.,Ltd. 58
Chemsky（shanghai）International Co.,Ltd. 50
Shandong Xiya Chemical Co., Ltd 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 62

View Lastest Price from 1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Palmitoyl-sn-glycero-3-phosphocholine pictures 2026-08-25 1-Palmitoyl-sn-glycero-3-phosphocholine
17364-16-8
 $2.20-8.80 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
1-Palmitoyl-sn-glycero-3-phosphocholine pictures 2026-07-16 1-Palmitoyl-sn-glycero-3-phosphocholine
17364-16-8
 $39.00-98.00 99.85% 10g TargetMol Chemicals Inc.
Phosphonylcholine Impurity pictures 2025-12-16 Phosphonylcholine Impurity
17364-16-8
 10mg 99%+ HPLC 1000 Moxin Chemicals

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Spectrum

1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(17364-16-8)1HNMR

17364-16-8(1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE)Related Search:

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P-LYSO-PC L-ALPHA-PALMITOYL-LYSOPHOSPHATIDYLCHOLINE L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, PALMITOYL L-GAMMA-PALMITOYL-ALPHA-LYSOLECITHIN LYSOLECITHIN, PALMITOYL LYSO-PPC 3-SN-LYSOPHOSPHATIDYLCHOLINE, 1-PALMITOYL 1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-PALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 1-PALMITOYL-2-LYSO-SN-GLYCERO-3-PHOSPHOCHOLINE 1-HEXADECANOYL-SN-GLYCEROL-3-PHOSPHORYLCHOLINE L-A-LYSOPHOSPHATIDYLCHOLINE, PALMITOYL 1-hexadecanoyl-sn-glycero-3-phosphocholine 1-Hexadecanoyl-sn-glycero-3-phosphocholine, 3-sn-Lysophosphatidylcholine, 1-palmitoyl, L-α-Palmitoyl-lysophosphatidylcholine, L-γ-Palmitoyl-α-lysolecithin, Lysolecithin, palmitoyl [O-[1-O-Hexadecanoyl-L-glycero-3-phospho]choline]anion 1-Hexadecylglycero-3-phosphocholine 1-Palmitoyl-2-lyso-sn-glycero-3-phosphatidylcholine 1-Palmitoylglycero-3-phosphocholine Palmitoyllysophosphatidylcholine L-α-Palmitoyl-lysophosphatidylcholine L-γ-Palmitoyl-α-lysolecithin, Lysolecithin Palmitoyl Lyso-phosphocholine 1-PalMitoyl-2-hydroxy-sn-glycero-3-phosphocholine (P-lysoPC, LPC) (7R)-3,5,9-4,7-Dihydroxy-N,N,N-triMethyl-10-oxotrioxa-4-phosphapentacosan-1-aMiniuM 4-Oxide Inner Salt 1-Hexadecanoyllysolecithin 1-O-PalMitoyl-2-lyso-sn-glycero-3-p L-g-PalMitoyl-a-lysolecithin 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, sodiuM salt (DSPG) L-γ-Palmitoyl-α-lysolecithin L-A-LYSOPHOSPHATIDYLCHOLINE, PALMITO 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC 1-Palmitoyl-sn-glycero-3-phosphocholine(P-LysoPC) Palmitoyl phosphocholine Choline Impurity 1 (R)-2-Hydroxy-3-(palmitoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate 3,5,9-Trioxa-4-phosphapentacosan-1-aminium,4,7-dihydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide, (7R)- 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC MaxSpec Standard LysoFos Choline 16 1-Pal PC P-LySOPC 1-Hexadecanyl-sn-propythritol phosphatidylcholine 1-Palmitoyl-sn-glycero-3-phosphocholine 1-Hexadecanoyl-sn-propythritol phosphatidylcholine P-lyso-PC (short route) 1-Palmitoyl-sn-glycero-3-phosphocholine【L5254】 1-Hexadecanoyl-SN-glycerol-phosphocholine Lecithin Impurity 49 L-Palmitoyllysolecithin P-LysoPC (16:0 Lyso PC) 16:0 LYSO PC 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOCHOLINE LYSO-PC 16:0 Lyso PC (1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine) 17364-16-8 C24H50NO7P C24H510NO7P Lipids Glycerophosphonocholines Glycerides