Ethylmagnesium bromide
- CAS No.
- 925-90-6
- Chemical Name:
- Ethylmagnesium bromide
- Synonyms
- AcroSeal;bromoethyl-magnesiu;Ethylmagnesium;Ethylbromomagnesium;1M;EtMgBr;2M in THF;28mm,2.5ML／CM;18mm,1.1ml/cm;24mm,1.8ML／CM
- CBNumber:
- CB8696160
- Molecular Formula:
- C2H5BrMg
- Molecular Weight:
- 133.27
- MDL Number:
- MFCD00000043
- MOL File:
- 925-90-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethylmagnesium bromide solution 1.0?M in THF | 364673 | 4X25ML | $108 |
| Ethylmagnesium bromide solution 3.0M in diethyl ether | 189871 | 4x25ml | $64.5 |
| Ethylmagnesium bromide solution 3.0M in diethyl ether | 189871 | 8l | $2480 |
| Ethylmagnesium Bromide (39% in Ethyl Ether, ca. 3mol/L) | E0134 | 250g | $88 |
| Ethylmagnesium Bromide (13% in Tetrahydrofuran, ca. 1mol/L) | E0497 | 250g | $101 |
| More product size | |||
| Melting point | -116.3°C |
|---|---|
| Boiling point | 34.6°C |
| Density | 1.02 g/mL at 25 °C |
| Flash point | <−30 °F |
| storage temp. | water-free area |
| solubility | Miscible in alcohols, ketones, esters, ethers, hydrocarbons. |
| form | Solution |
| color | Pale yellow to brown |
| Water Solubility | Reacts with water. |
| Sensitive | Air & Moisture Sensitive |
| BRN | 3587203 |
| Exposure limits |
ACGIH: TWA 400 ppm; STEL 500 ppm OSHA: TWA 400 ppm(1200 mg/m3) NIOSH: IDLH 1900 ppm |
| InChI | InChI=1S/C2H5.BrH.Mg/c1-2;;/h1H2,2H3;1H;/q;;+1/p-1 |
| InChIKey | TWTWFMUQSOFTRN-UHFFFAOYSA-M |
| SMILES | C(C)[Mg]Br |
| CAS DataBase Reference | 925-90-6(CAS DataBase Reference) |
| FDA UNII | 5564378HK3 |
| EPA Substance Registry System | Magnesium, bromoethyl- (925-90-6) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS02,GHS05,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H224-H361-H371-H372-H303-H318-H225-H250-H260-H314-H261-H302-H335-H351-H336 | |||||||||
| Precautionary statements | P201-P202-P233-P240-P241+P242+P243-P260-P264-P270-P271-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P308+P313-P335+P334-P308+P311-P210-P222-P223-P231+P232-P370+P378-P422-P280-P305+P351+P338-P310-P402+P404-P403+P235-P261-P303+P361+P353-P405-P501a | |||||||||
| target organs | Central nervous system | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | F+,C,F | |||||||||
| Risk Statements | 12-14/15-19-22-34-66-67-40-11-14-37 | |||||||||
| Safety Statements | 16-26-36/37/39-43-45-7/8-27-9 | |||||||||
| RIDADR | UN 3399 4.3/PG 1 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | LU5950000 | |||||||||
| F | 1-3-10 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 4.3 | |||||||||
| PackingGroup | I | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 4.3 - Hazardous materials which set free flammable gases upon contact with water | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Flam. Liq. 2 Skin Corr. 1B STOT SE 3 Water-react 1 |
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| Excepted Quantities | Not Permitted as Excepted Quantity | |||||||||
| NFPA 704 |
|
Ethylmagnesium bromide price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 364673 | Ethylmagnesium bromide solution 1.0?M in THF | 925-90-6 | 4X25ML | $108 | 2026-04-30 | Buy |
| Sigma-Aldrich | 189871 | Ethylmagnesium bromide solution 3.0M in diethyl ether | 925-90-6 | 4x25ml | $64.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 189871 | Ethylmagnesium bromide solution 3.0M in diethyl ether | 925-90-6 | 8l | $2480 | 2026-04-30 | Buy |
| TCI Chemical | E0134 | Ethylmagnesium Bromide (39% in Ethyl Ether, ca. 3mol/L) | 925-90-6 | 250g | $88 | 2026-04-30 | Buy |
| TCI Chemical | E0497 | Ethylmagnesium Bromide (13% in Tetrahydrofuran, ca. 1mol/L) | 925-90-6 | 250g | $101 | 2026-04-30 | Buy |
Ethylmagnesium bromide Chemical Properties,Uses,Production
Chemical Properties
Ethylmagnesium bromide is generally sold as a dark brown solution and can be dissolved in diethyl ether, butyl ether, isopropyl ether, THF and anisole.
Uses
Ethylmagnesium Bromide is a useful reagent in preparation of zirconium complexes having two phenoxy-imine chelate ligands for olefin polymerization.
Preparation
Ethylmagnesium bromide is commercially available, usually as a solution in diethyl ether or tetrahydrofuran. It may be prepared in the normal manner of Grignard reagents — by reacting bromoethane with magnesium in diethyl ether:
EtBr + Mg → EtMgBr
Application
Ethylmagnesium bromide is a Grignard reagent widely used in organic chemical synthesis. It can be employed in the following chemical reactions:
(1) The cleavage effect on pentafluorophenylphosphine bonds and sulphur bonds: Reactions between tri(pentafluorophenyl)phosphine and bis(pentafluorophenyl)sulphide with ethylmagnesium bromide yield products indicating the pentafluorophenyl group detaches from both phosphorus and sulphur[1].
(2) Reaction with unsaturated organotin compounds to form saturated compounds: Its reaction with tri-n-butylstannylacetylene in diethyl ether removes ethane, ethylene, acetylene, and ethylacetylene, yielding ethyl tri-n-butylstannyl and bis-1,2-tri-n-butylstannyl ethane[2].
(3) Facilitating selective transformation of cyclopropyl groups: In the case of the tetrahydrofuran-protected racemic diethyl malonate 1, selective conversion of the cyclopropyl group is achieved via a reductive cyclopropanation reaction using ethylmagnesium bromide in the presence of tetrahydrofuran. This ultimately enables the isolation of the ethoxycarbonyl group from diethyl malonate[3].
Reactions
Ethylmagnesium bromide reacts with water to produce ethane.
CH3CH2MgBr+H2O→CH3-CH3+Mg(OH)Br
Reaction of ethylmagnesium bromide with ethyl acetate in the presence of styrene and titanium(IV) isopropoxide as a catalyst leads to (Z)-1-methyl-2-phenylcyclopropanol in 42% yield.
General Description
Ethylmagnesium bromide, an organomagnesium compound, is commonly known as Grignard reagent. It is a powerful carbon nucleophile mainly used for C-C bond formation. Ethylmagnesium bromide solution (3.0 M in diethyl ether) can be used for copper(I)-catalyzed allylic substitution reaction.
Grignard reagents are organometallic compounds discovered by a French chemist, Victor Grignard in 1900. These compounds can be obtained as a formula “RMgX” by the reaction of halogenated hydrocarbons with magnesium metal in anhydrous solvents such as diethyl ether,1) and have been widely used in organic synthesis.
Hazard
Flammable, dangerous fire risk.
reaction suitability
reaction type: Grignard Reaction
References
[1] STEPHEN A. SICREE Christ T. Cleavage of pentafluorophenyl-phosphorus and -sulfur bonds by ethylmagnesium bromide[J]. Journal of Fluorine Chemistry, 1992, 59 2: Pages 269-273. https://doi.org/10.1016/S0022-1139(00)82419-7.
[2] A. N. NESMEYANOV I. S S A E BORISOV. ChemInform Abstract: REACTIONS OF ETHYLMAGNESIUM BROMIDE WITH SOME UNSATURATED ORGANOTIN COMPOUNDS[J]. ChemInform, 1976, 7 4. https://doi.org/10.1002/chin.197604258.
[3] ANDREI V. BEKISH Oleg G K. Differentiation between the ethoxycarbonyl groups in diethyl malate via their titanium-catalyzed reductive cyclopropanation with ethylmagnesium bromide and subsequent site-selective three-carbon ring cleavage[J]. Tetrahedron Letters, 2005, 46 41: Pages 6975-6978. https://doi.org/10.1016/j.tetlet.2005.08.076.
Ethylmagnesium bromide Preparation Products And Raw materials
Raw materials
Preparation Products
1of4
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 | sales@qinmuchem.com | China | 1008 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 427 | 58 |
| ANHUI CHICO CHEMICAL CO., LTD. | +8613057662806 | kirsten@chicopharm.com | China | 2619 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +8617392709771 | 1097@dideu.com | China | 3996 | 58 |
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3364 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Wuhan Ruichi Technology Co., Ltd | +8613545065237 | admin@whrchem.com | China | 153 | 58 |
| Rongchuang International | +8613175533356 | kevin@rongchuangintl.com | China | 272 | 58 |
Related articles
- Ethylmagnesium Bromide: A Versatile Reagent in Organic Synthesis
- Ethylmagnesium bromide (EtMgBr) is a crucial organometallic compound widely used in organic synthesis.
- Oct 21，2024
View Lastest Price from Ethylmagnesium bromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-02 | Ethylmagnesium bromide
925-90-6
|
US $1.00 / g | 1g | 99% | 100kg | RongNa Biotechnology Co.,Ltd | |
 |
2026-05-02 | Ethylmagnesium bromide
925-90-6
|
US $0.00 / kg | 1kg | 99% | 99999 | Rongchuang International | |
 |
2026-03-20 | ETHYLMAGNESIUM BROMIDE
925-90-6
|
US $1.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Ethylmagnesium bromide
925-90-6
- US $1.00 / g
- 99%
- RongNa Biotechnology Co.,Ltd
-
- Ethylmagnesium bromide
925-90-6
- US $0.00 / kg
- 99%
- Rongchuang International
-
- ETHYLMAGNESIUM BROMIDE
925-90-6
- US $1.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
