ChemicalBook >> CAS DataBase List >>H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH structure

CAS No.: 568565-11-7

Chemical Name:: H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH

Synonyms: QRPRLSHKGPMPA;[ALA13]-APELIN-13;[Ala13]-Apelin-13 - 1 mg;(Ala13)-Apelin-13 ，P1212;[Ala13]Apelin 13 (human, mouse, rat, bovine);(ALA13)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT);GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA;[Ala13]Apelin-13, human, bovine, mouse, rat (F13A) (2);H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH;(Ala??)-Apelin-13 (human, bovine, mouse, rat) acetate salt

CBNumber:: CB8697662

Molecular Formula:: C63H107N23O16S

Molecular Weight:: 1474.73

MDL Number:: MFCD08459499

MOL File:: 568565-11-7.mol

MSDS File:: SDS

Last updated:2026-01-13 11:26:13

Product description	Number	Pack Size	Price
[Ala13]-Apelin-13 trifluoroacetate salt ≥96% (HPLC)	SML2083	1 mg	$128.25
[Ala13]-Apelin-13 trifluoroacetate salt ≥96% (HPLC)	SML2083	5 mg	$545
(Ala13)-Apelin-13 (human, bovine, mouse, rat) trifluoroacetate salt H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH trifluoroacetate salt	FA109791	5mg	$546
[ALA13]- APELIN-13-HUMAN 95.00%	PEP0000066	1MG	$648.83
(Ala13)-Apelin-13 (human, bovine, mouse, rat) acetate salt H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH acetate salt	FA110249	25mg	$904

Request For Quotation

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH Properties

Density	1.52±0.1 g/cm3(Predicted)
storage temp.	-20°C
form	powder
pka	3.70±0.10(Predicted)
color	white to beige
Sequence	Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala
UNSPSC Code	51111800
NACRES	NA.77

SAFETY

Risk and Safety Statements

WGK Germany	WGK 3
Storage Class	11 - Combustible Solids

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML2083	[Ala13]-Apelin-13 trifluoroacetate salt ≥96% (HPLC)	568565-11-7	1 mg	$128.25	2025-07-31	Buy
Sigma-Aldrich	SML2083	[Ala13]-Apelin-13 trifluoroacetate salt ≥96% (HPLC)	568565-11-7	5 mg	$545	2025-07-31	Buy
Biosynth Carbosynth	FA109791	(Ala13)-Apelin-13 (human, bovine, mouse, rat) trifluoroacetate salt H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH trifluoroacetate salt	568565-11-7	5mg	$546	2021-12-16	Buy
American Custom Chemicals Corporation	PEP0000066	[ALA13]- APELIN-13-HUMAN 95.00%	568565-11-7	1MG	$648.83	2021-12-16	Buy
Biosynth Carbosynth	FA110249	(Ala13)-Apelin-13 (human, bovine, mouse, rat) acetate salt H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH acetate salt	568565-11-7	25mg	$904	2021-12-16	Buy

Product number	Packaging	Price	Buy
SML2083	1 mg	$128.25	Buy
SML2083	5 mg	$545	Buy
FA109791	5mg	$546	Buy
PEP0000066	1MG	$648.83	Buy
FA110249	25mg	$904	Buy

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH Chemical Properties,Uses,Production

Uses

(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway[1].

Biological Activity

(Ala13)-Apelin-13 corresponds to Apelin-13 with a Phe-to-Ala substitution at the C-terminus (F13A) and functions as an antagonist against apelin-dependent APJ functions both in cultures and in animal studies in vivo.

in vivo

(Ala13)-Apelin-13 (1-300 pmol/60 nl; microinjected into the DVC) decreases gastric tone and motility in a dose-dependent manner in rats^[1].

Animal Model:	250-300 g, Sprague-Dawley rats^[1]
Dosage:	1-300 pmol/60 nl
Administration:	Microinjected into the DVC (dorsal vagal complex (DVC)
Result:	Decreased gastric tone and motility in a dose-dependent manner with D50?≈?27 pmol for both antrum and corpus.

References

[1] Bülbül M, et al. Apelin-13 inhibits gastric motility through vagal cholinergic pathway in rats. Am J Physiol Gastrointest Liver Physiol. 2018 Feb 1;314(2):G201-G210. DOI:10.1152/ajpgi.00223.2017
[2] O'Harte FPM,et al. Acylated apelin-13 amide analogues exhibit enzyme resistance and prolonged insulin releasing, glucose lowering and anorexic properties. Biochem Pharmacol. 2017 Dec 15;146:165-173. DOI:10.1016/j.bcp.2017.10.002

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH Suppliers

Global( 67)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	995	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19654	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39042	58
Nanjing TGpeptide	+86-13347807150	support@tgpeptide.com	China	3279	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Changsha MOL Changes Biotechnology Co., Ltd.	+8619375158599	info@molchanges.com	China	5218	58
LEON (NANJING) BIOTECHNOLOGY CO., LTD.	+8615051830413	sales.njleonbiotech@gmail.com	China	5482	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Cellmano Biotech Limited	58
BOC Sciences	58
Chengdu Youngshe Chemical Co., Ltd.	58
TargetMol Chemicals Inc.	58
Nanjing TGpeptide	58
Aladdin Scientific	58
Changsha MOL Changes Biotechnology Co., Ltd.	58
LEON (NANJING) BIOTECHNOLOGY CO., LTD.	58
GL Biochem (Shanghai) Ltd	64

568565-11-7(H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH)Related Search:

GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE APELIN-15 (63-77) H-LYS-PHE-ARG-ARG-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH APELIN PRECURSOR (61-77) (HUMAN, BOVINE, MOUSE, RAT) TRIFLUOROACETATE APELIN (65-77) (N15-ARG 66) [HOMO SAPIENS]/[MUS MUSCULUS]/[BOS TAURUS]

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH

1of2

QRPRLSHKGPMPA [ALA13]-APELIN-13 (ALA13)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT) (Ala13)-Apelin-13 (human, bovine, mouse, rat) trifluoroacetate salt H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH trifluoroacetate salt (Ala13)-Apelin-13 (human, bovine, mouse, rat) acetate salt H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH acetate salt H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH [Ala13]Apelin-13, human, bovine, mouse, rat (F13A) (2) [Ala13]Apelin 13 (human, mouse, rat, bovine) GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala ((2) Due to the presence of a Gln in N-terMinal position this peptide can contain the pyroglutaMic forM) L-Alanine, L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl- L-Glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-alanine (Ala??)-Apelin-13 (human, bovine, mouse, rat) acetate salt [Ala13]-Apelin-13 - 1 mg (Ala13)-Apelin-13 ，P1212 568565-11-7 C63H107N23O16SxC2H4O2 C63H107N23O16SxC2HF3O2 C63H107N23O16S peptide Apelin receptor