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4-Bromo-3,5-dimethyl-benzonitrile

4-Bromo-3,5-dimethyl-benzonitrile structure

CAS No.: 75344-77-3

Chemical Name:: 4-Bromo-3,5-dimethyl-benzonitrile

Synonyms: 5-DIMETHYL-BENZONITRILE;2-Bromo-5-cyano-m-xylene;3,5-Dimethyl-4-bromobenzonitrile;4-BROMO-3,5-DIMETHYL-BENZONITRILE;Benzonitrile,4-bromo-3,5-dimethyl-;4-Bromo-3,5-dimethylbenzonitrile 98%;4-BroMo-3,5-diMethylbenzonitrile, 97%+;4-Bromo-3,5-dimethyl-benzonitrile, CAS 75344-77-3;4-BROMO-3,5-DIMETHY4-BROMO-3,5-DIMETHYL-BENZONITRILEL-BENZONITRILE

CBNumber:: CB8743996

Molecular Formula:: C9H8BrN

Molecular Weight:: 210.07

MDL Number:: MFCD07369910

MOL File:: 75344-77-3.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:49

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4-Bromo-3,5-dimethyl-benzonitrile Properties

Melting point	135-137℃
Boiling point	291℃
Density	1.44
Flash point	130℃
storage temp.	Sealed in dry,Room Temperature
Appearance	White to off-white Solid
InChI	InChI=1S/C9H8BrN/c1-6-3-8(5-11)4-7(2)9(6)10/h3-4H,1-2H3
InChIKey	AVXHSMPHQGFXRG-UHFFFAOYSA-N
SMILES	C(#N)C1=CC(C)=C(Br)C(C)=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332
Precautionary statements	P280
HS Code	2926907090

4-Bromo-3,5-dimethyl-benzonitrile price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B691578	4-Bromo-3,5-dimethylbenzonitrile	75344-77-3	100mg	$45	2021-12-16	Buy
TRC	B691578	4-Bromo-3,5-dimethylbenzonitrile	75344-77-3	500mg	$65	2021-12-16	Buy
Matrix Scientific	075040	4-Bromo-3,5-dimethylbenzonitrile 95+%	75344-77-3	1g	$100	2021-12-16	Buy
Biosynth Carbosynth	FB31344	4-Bromo-3,5-dimethylbenzonitrile	75344-77-3	5G	$100	2021-12-16	Buy
SynQuest Laboratories	3737-9-04	4-Bromo-3,5-dimethylbenzonitrile	75344-77-3	5G	$180	2021-12-16	Buy

Product number	Packaging	Price	Buy
B691578	100mg	$45	Buy
B691578	500mg	$65	Buy
075040	1g	$100	Buy
FB31344	5G	$100	Buy
3737-9-04	5G	$180	Buy

4-Bromo-3,5-dimethyl-benzonitrile Chemical Properties,Uses,Production

Synthesis

Benzene, 2-bromo-5-(bromomethyl)-1,3-dimethyl-

35510-00-0

75344-77-3

General procedure for the synthesis of 4-bromo-3,5-dimethylbenzonitrile from 2-bromo-5-(bromomethyl)-1,3-xylene: 2-bromo-5-(bromomethyl)-1,3-xylene (0.9 g, 3.24 mmol) was added to a 100 mL three-necked flask at room temperature. Ammonium hydroxide (4.41 g, 64.8 mmol) and iodine (0.8 g, 6.28 mmol) were added slowly under stirring. The reaction mixture was heated to 60 °C in acetonitrile (9 mL) under nitrogen protection and kept at this temperature for 4 hours. The progress of the reaction was monitored by TLC and the heating was stopped after confirming the complete reaction of the ingredients. The reaction mixture was cooled to room temperature (20-30 °C) and the solvent was removed by evaporation at 40 °C under reduced pressure. To the residue, 20 mL of ethyl acetate was added for liquid-liquid separation. The organic phase was washed sequentially with 10 mL of water and 10 mL of saturated aqueous sodium chloride. The organic phase was dried with anhydrous sodium sulfate and concentrated to give 0.7 g of 4-bromo-3,5-dimethylbenzonitrile crude as a light yellow waxy solid. The crude was recrystallized by 1 mL of isopropanol to give an off-white solid. Yield: 0.5 g, yield: 73.5%.

References

[1] Patent: CN107417571, 2017, A. Location in patent: Paragraph 0058-0062; 0072-0076; 0094-0098

4-Bromo-3,5-dimethyl-benzonitrile Preparation Products And Raw materials

Raw materials

Benzene, 2-bromo-5-(bromomethyl)-1,3-dimethyl- iodine Acetonitrile Ammonium hydroxide

Preparation Products

Boron Standard Metal Solution

4-Bromo-3,5-dimethyl-benzonitrile Suppliers

Global( 185)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29733	60
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2136	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49730	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29802	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10035	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Zhejiang ZETian Fine Chemicals Co. LTD	58
Changzhou Ansciep Chemical Co., Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Fuxin Pharmaceutical	58

View Lastest Price from 4-Bromo-3,5-dimethyl-benzonitrile manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-04-20	4-bromo-3,5-dimethyl-benzonitrile 75344-77-3	US $1400.00 / Kg	1Kg	98	500 Kg	R&D Scientific Inc.
	2020-01-01	4-BROMO-3,5-DIMETHYL-BENZONITRILE 75344-77-3	US $1.00 / KG	1KG	99%	200kg	Career Henan Chemical Co

4-bromo-3,5-dimethyl-benzonitrile
75344-77-3
US $1400.00 / Kg
98
R&D Scientific Inc.

4-BROMO-3,5-DIMETHYL-BENZONITRILE
75344-77-3
US $1.00 / KG
99%
Career Henan Chemical Co

4-Bromo-3,5-dimethyl-benzonitrile Spectrum

4-Bromo-3,5-dimethyl-benzonitrile(75344-77-3)¹HNMR

75344-77-3(4-Bromo-3,5-dimethyl-benzonitrile)Related Search:

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