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BOC-SER(TOS)-OCH3

CAS No.
56926-94-4
Chemical Name:
BOC-SER(TOS)-OCH3
Synonyms
BOC-SER(TOS)-OME;BOC-SER(TOS)-OCH3;BOC-L-SER(OTS)-OME;Boc-L-Ser(Tos)-OCH3;REF DUPL: Boc-Ser(Tos)-OMe;N-Boc-O-tosylserine methyl ester;(Tert-Butoxy)Carbonyl Ser(Tos)-OMe;N-Boc-O-tosyl-L-serine Methyl Ester;methyl N-(tert-butoxycarbonyl)-O-tosyl-L-serinate;N-Boc-3-(p-toluenesulfonyloxy)-L-serine Methyl ester, 98%
CBNumber:
CB8767228
Molecular Formula:
C16H23NO7S
Molecular Weight:
373.42
MDL Number:
MFCD01632224
MOL File:
56926-94-4.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:50
Product description Number Pack Size Price
Boc-Ser(Tos)-OMe J93724 1g $14
Boc-Ser(Tos)-OMe 97+% AS33268 1g $23
Boc-Ser(Tos)-OMe 95+% 075711 1g $59
L-Serine,N-[(1,1-dimethylethoxy)carbonyl]-O-[(4-methylphenyl)sulfonyl]-,methylester CS-M3183 10g $59
Boc-Ser(Tos)-OMe FB72160 5G $63
More product size

BOC-SER(TOS)-OCH3 Properties

Melting point 74-75℃
Boiling point 520.0±50.0 °C(Predicted)
Density 1.236
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 10.28±0.46(Predicted)
form Powder
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

BOC-SER(TOS)-OCH3 price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific J93724 Boc-Ser(Tos)-OMe 56926-94-4 1g $14 2021-12-16 Buy
Activate Scientific AS33268 Boc-Ser(Tos)-OMe 97+% 56926-94-4 1g $23 2021-12-16 Buy
Matrix Scientific 075711 Boc-Ser(Tos)-OMe 95+% 56926-94-4 1g $59 2021-12-16 Buy
ChemScene CS-M3183 L-Serine,N-[(1,1-dimethylethoxy)carbonyl]-O-[(4-methylphenyl)sulfonyl]-,methylester 56926-94-4 10g $59 2021-12-16 Buy
Biosynth Carbosynth FB72160 Boc-Ser(Tos)-OMe 56926-94-4 5G $63 2021-12-16 Buy
Product number Packaging Price Buy
J93724 1g $14 Buy
AS33268 1g $23 Buy
075711 1g $59 Buy
CS-M3183 10g $59 Buy
FB72160 5G $63 Buy

BOC-SER(TOS)-OCH3 Chemical Properties,Uses,Production

Uses

Boc-Ser(Tos)-OMe is a serine derivative[1].

Synthesis

Boc-L-serine methyl ester

2766-43-0

Tosyl chloride

98-59-9

BOC-SER(TOS)-OCH3

56926-94-4

To a pyridine (10 mL) solution of Boc-L-serine methyl ester (0.67 g, 3.1 mmol) cooled in an ice bath was added p-toluenesulfonyl chloride (3.0 g, 15.7 mmol). The reaction mixture was stirred in an ice bath under nitrogen protection for 8 hours. Subsequently, ether (10 mL) was added to the reaction system and the mixture was transferred to room temperature to continue stirring for 14 hours. Upon completion of the reaction, the reaction solution was washed sequentially with deionized water, 10% potassium bisulfate solution, saturated sodium bicarbonate solution and brine. The organic layer was separated, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. The colorless oil obtained was purified by silica gel column chromatography (eluent ratio hexane:ethyl acetate=2:1) to afford (S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(p-toluyloxy)propionate (1.05 g, 91% yield) as a white solid. The spectral data of the product were in agreement with literature reports and the purity was confirmed by 1H NMR.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

BOC-SER(TOS)-OCH3 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 122)Suppliers
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View Lastest Price from BOC-SER(TOS)-OCH3 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BOC-SER(TOS)-OCH3 pictures 2019-12-26 BOC-SER(TOS)-OCH3
56926-94-4
US $1.00 / KG 1KG ≥98% g/kg/Ton Career Henan Chemical Co
N-Boc-3-(p-toluenesulfonyloxy)-L-serine Methyl ester, 98% L-Serine,N-[(1,1-diMethylethoxy)carbonyl]-O-[(4-Methylphenyl)sulfonyl]-, Methyl ester methyl N-(tert-butoxycarbonyl)-O-tosyl-L-serinate (Tert-Butoxy)Carbonyl Ser(Tos)-OMe BOC-L-SER(OTS)-OME BOC-SER(TOS)-OCH3 BOC-SER(TOS)-OME Boc-L-Ser(Tos)-OCH3 (S)-methyl 2-(tert-butoxycarbonylamino)-3-(tosyloxy)propanoate REF DUPL: Boc-Ser(Tos)-OMe Methyl (2S)-2-[N-(t-butoxycarbonyl)aMino]-3-(4-Methylbenzenesulfonyl)-oxypropionate Methyl (2S)-2-[N-(tert-butoxycarbonyl)amino]-3-[[(4-methylphenyl)sulfonyl]oxy]propionate N-Boc-O-tosylserine methyl ester methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[(4-methylbenzenesulfonyl)oxy]propanoate (2S)-3-(4-methylphenyl)sulfonyloxy-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoic acid methyl ester N-Boc-O-tosyl-L-serine Methyl Ester 56926-94-4 C16H23NO7S Amino Acid Derivatives Boc-Amino Acids and Derivative Boc-Amino acid series