4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID
- CAS No.
- 152529-79-8
- Chemical Name:
- 4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID
- Synonyms
- 4-(2,6-Dioxo-1-propyl-2,3,6,9-tetrahydro-1H-purin-8-yl)benzenesulfonic acid;4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid;4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID;BENZENESULFONIC ACID,4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-;Benzenesulfonic acid, 4-(2,3,6,9-tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-
- CBNumber:
- CB8784470
- Molecular Formula:
- C14H14N4O5S
- Molecular Weight:
- 350.35
- MDL Number:
- MFCD06411605
- MOL File:
- 152529-79-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| PSB1115 | B6922 | 5mg | $82 |
| PSB1115 | B6922 | 10mg | $147 |
| PSB1115 | B6922 | 25mg | $327 |
| 4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonicacid 95% | CM266074 | 1g | $790 |
| 4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonicacid 95+% | CD11249380 | 1g | $845 |
| Melting point | >300 °C |
|---|---|
| Density | 1.522±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C, protect from light |
| solubility | Soluble to 100 mM in DMSO and to 20 mM in water with gentle warming |
| form | Powder |
| pka | -1.59±0.50(Predicted) |
| color | Off-white to light brown |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | B6922 | PSB1115 | 152529-79-8 | 5mg | $82 | 2021-12-16 | Buy |
| ApexBio Technology | B6922 | PSB1115 | 152529-79-8 | 10mg | $147 | 2021-12-16 | Buy |
| ApexBio Technology | B6922 | PSB1115 | 152529-79-8 | 25mg | $327 | 2021-12-16 | Buy |
| Chemenu | CM266074 | 4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonicacid 95% | 152529-79-8 | 1g | $790 | 2021-12-16 | Buy |
| Crysdot | CD11249380 | 4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonicacid 95+% | 152529-79-8 | 1g | $845 | 2021-12-16 | Buy |
4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID Chemical Properties,Uses,Production
Uses
PSB-1115 is a selective A2B Adenosine Receptor antagonist. PSB-1115 inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh)[1].
Definition
ChEBI: 4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)benzenesulfonic acid is an oxopurine.
in vivo
PSB-1115 (0.5 mg/kg; i.p.; single dose, injected 20 minutes before inhalation) antagonizes the inhibitory effect of the non-selective adenosine receptor agonist NECA (HY-103173) on mucociliary clearance in mice[2].
IC 50
A2BR
storage
Store at RT
References
[1] Michael S, et al. Adenosine A(2A) agonist and A(2B) antagonist mediate an inhibition of inflammation-induced contractile disturbance of a rat gastrointestinal preparation. Purinergic Signal. 2010 Mar;6(1):117-24. DOI:10.1007/s11302-009-9174-y
4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +8613382787392 | sales@aeechem.com | China | 10000 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 86249 | 60 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2984 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4032 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4887 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59936 | 58 |
| Shanghai Zhongzechuan Pharmaceutical Technology Co., LTD | 25888888 15021253307 | sales@wesyntech.com | China | 497 | 58 |
