6-Bromobenzofuran
- CAS No.
- 128851-73-0
- Chemical Name:
- 6-Bromobenzofuran
- Synonyms
- 6-Bromo-1-benzofuran;6-Bromo-benzofuran;6-Bromobenzo[b]furan;BENZOFURAN, 6-BROMO-
- CBNumber:
- CB8798082
- Molecular Formula:
- C8H5BrO
- Molecular Weight:
- 197.03
- MDL Number:
- MFCD08669477
- MOL File:
- 128851-73-0.mol
- MSDS File:
- SDS
| Boiling point | 234℃ |
|---|---|
| Density | 1.608 |
| Flash point | 95℃ |
| storage temp. | 2-8°C |
| solubility | Chloroform, Dichloromethane, Ethyl Acetate |
| form | Oil |
| color | Light Yellow |
| Stability | Volatile |
| InChI | InChI=1S/C8H5BrO/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5H |
| InChIKey | BBXQYOQXGGJUFK-UHFFFAOYSA-N |
| SMILES | O1C2=CC(Br)=CC=C2C=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2932990090 |
6-Bromobenzofuran price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS18179 | 6-Bromobenzofuran 97% | 128851-73-0 | 1g | $68 | 2026-06-04 | Buy |
| Activate Scientific | AS18179 | 6-Bromobenzofuran 97% | 128851-73-0 | 5g | $251 | 2026-06-04 | Buy |
| Matrix Scientific | 119928 | 6-Bromobenzofuran | 128851-73-0 | 1.00g | $60 | 2026-05-18 | Buy |
| Matrix Scientific | 119928 | 6-Bromobenzofuran | 128851-73-0 | 5.00g | $214 | 2026-05-18 | Buy |
| Matrix Scientific | 119928 | 6-Bromobenzofuran | 128851-73-0 | 25.00g | $951 | 2026-05-18 | Buy |
6-Bromobenzofuran Chemical Properties, Uses, Production
Chemical Properties
Light Yellow Oil
Synthesis
204452-94-8
128851-73-0
128868-60-0
Polyphosphoric acid (PPA, 0.743 g, 6.83 mmol) was added to a solution of compound 175 (0.656 g, 2.28 mmol) in toluene (4.6 mL) under an argon atmosphere and stirred at room temperature. The reaction mixture was heated to reflux and maintained for 4 hours. Upon completion of the reaction, it was cooled to room temperature and the reaction was quenched with ice water and subsequently extracted with ethyl acetate (EtOAc). The organic layers were combined, washed with saturated brine, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure. The crude products were purified by silica gel column chromatography (eluent: ethyl acetate/hexane, 2:98) to afford 6-bromobenzofuran (176, main product, 0.206 g, 1.05 mmol, 46% yield) and 4-bromobenzofuran (177, by-product, 0.183 g, 0.935 mmol, 41% yield, colorless oily substance), respectively. 1H-NMR (CDCl3, 400 MHz) data for 6-bromobenzofuran (176): δ 6.75 (d, J = 1.6 Hz, 1H, furan-H), 7.36 (dd, J = 1.2, 8.4 Hz, 1H, Ar-H), 7.46 (d, J = 8.4 Hz, 1H, Ar-H), 7.60 (d, J = 1.6 Hz 1H, furan-H), 7.69 (s, 1H, Ar-H). 1H-NMR (CDCl3, 400 MHz) data for 4-bromobenzofuran (177): δ 6.82 (d, J = 2.4 Hz, 1H, furan-H), 7.17 (dd, J = 7.6, 8.4 Hz, 1H, Ar-H), 7.40 (d, J = 7.6 Hz, 1H, Ar-H), 7.45 (d, J = 8.4 Hz 1H, Ar-H), 7.66 (d, J = 2.4 Hz, 1H, furan-H).
References
[1] Phytochemistry, 2013, vol. 96, p. 132 - 147
[2] Patent: US7045545, 2006, B1. Location in patent: Page/Page column 20
[3] Patent: EP1204659, 2003, B1. Location in patent: Page/Page column 15-16
[4] Journal of Medicinal Chemistry, 1997, vol. 40, # 3, p. 322 - 330
[5] Tetrahedron, 2015, vol. 71, # 29, p. 4835 - 4841
6-Bromobenzofuran Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Qianguang Trade Co., Ltd. | 020-39071117 18030085485 | 2797782741@qq.com | China | 291 | 55 |
| Shanghai Naiys Biological Technology Co., Ltd | 18321139117 | 316441092@qq.con | China | 3194 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. | 21-57721279 18121011378 | sales@shydchem.com.cn | China | 998 | 56 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Aobo pharmaceutical Technology Co., Ltd | 86-21-51320499 | aobo@aobopharm.com | China | 297 | 57 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
View Latest Price from 6-Bromobenzofuran manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-09-02 | 6-Bromobenzofuran
128851-73-0
|
$1.00 | 1KG | 98% | 1kg; 2kg；10kg; 100kg | Career Henan Chemical Co |
-
- 6-Bromobenzofuran
128851-73-0
- $1.00
- 98%
- Career Henan Chemical Co
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