6-Bromobenzofuran
- CAS No.
- 128851-73-0
- Chemical Name:
- 6-Bromobenzofuran
- Synonyms
- 6-Bromo-benzofuran;6-Bromobenzo[b]furan;6-Bromo-1-benzofuran;BENZOFURAN, 6-BROMO-
- CBNumber:
- CB8798082
- Molecular Formula:
- C8H5BrO
- Molecular Weight:
- 197.03
- MDL Number:
- MFCD08669477
- MOL File:
- 128851-73-0.mol
| Boiling point | 234℃ |
|---|---|
| Density | 1.608 |
| Flash point | 95℃ |
| storage temp. | 2-8°C |
| solubility | Chloroform, Dichloromethane, Ethyl Acetate |
| form | Oil |
| color | Light Yellow |
| Stability | Volatile |
| InChI | InChI=1S/C8H5BrO/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5H |
| InChIKey | BBXQYOQXGGJUFK-UHFFFAOYSA-N |
| SMILES | O1C2=CC(Br)=CC=C2C=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2932990090 |
6-Bromobenzofuran price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B680180 | 6-Bromo-benzofuran | 128851-73-0 | 1g | $1135 | 2021-12-16 | Buy |
| SynQuest Laboratories | 2H10-9-68 | 6-Bromobenzofuran | 128851-73-0 | 5G | $1184 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB19200 | 6-Bromobenzofuran | 128851-73-0 | 500mg | $905 | 2021-12-16 | Buy |
| Matrix Scientific | 119928 | 6-Bromobenzofuran 95+% | 128851-73-0 | 1g | $1080 | 2021-12-16 | Buy |
| Matrix Scientific | 119928 | 6-Bromobenzofuran 95+% | 128851-73-0 | 250mg | $432 | 2021-12-16 | Buy |
6-Bromobenzofuran Chemical Properties,Uses,Production
Chemical Properties
Light Yellow Oil
Synthesis
204452-94-8
128851-73-0
128868-60-0
Polyphosphoric acid (PPA, 0.743 g, 6.83 mmol) was added to a solution of compound 175 (0.656 g, 2.28 mmol) in toluene (4.6 mL) under an argon atmosphere and stirred at room temperature. The reaction mixture was heated to reflux and maintained for 4 hours. Upon completion of the reaction, it was cooled to room temperature and the reaction was quenched with ice water and subsequently extracted with ethyl acetate (EtOAc). The organic layers were combined, washed with saturated brine, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure. The crude products were purified by silica gel column chromatography (eluent: ethyl acetate/hexane, 2:98) to afford 6-bromobenzofuran (176, main product, 0.206 g, 1.05 mmol, 46% yield) and 4-bromobenzofuran (177, by-product, 0.183 g, 0.935 mmol, 41% yield, colorless oily substance), respectively. 1H-NMR (CDCl3, 400 MHz) data for 6-bromobenzofuran (176): δ 6.75 (d, J = 1.6 Hz, 1H, furan-H), 7.36 (dd, J = 1.2, 8.4 Hz, 1H, Ar-H), 7.46 (d, J = 8.4 Hz, 1H, Ar-H), 7.60 (d, J = 1.6 Hz 1H, furan-H), 7.69 (s, 1H, Ar-H). 1H-NMR (CDCl3, 400 MHz) data for 4-bromobenzofuran (177): δ 6.82 (d, J = 2.4 Hz, 1H, furan-H), 7.17 (dd, J = 7.6, 8.4 Hz, 1H, Ar-H), 7.40 (d, J = 7.6 Hz, 1H, Ar-H), 7.45 (d, J = 8.4 Hz 1H, Ar-H), 7.66 (d, J = 2.4 Hz, 1H, furan-H).
References
[1] Phytochemistry, 2013, vol. 96, p. 132 - 147
[2] Patent: US7045545, 2006, B1. Location in patent: Page/Page column 20
[3] Patent: EP1204659, 2003, B1. Location in patent: Page/Page column 15-16
[4] Journal of Medicinal Chemistry, 1997, vol. 40, # 3, p. 322 - 330
[5] Tetrahedron, 2015, vol. 71, # 29, p. 4835 - 4841
6-Bromobenzofuran Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | sales@hbmojin.com | China | 12636 | 58 |
| Shanghai Gubang New Materail Technology Co. LTD | 21-51317962 +8618721305404 | 16728589@qq.com | CHINA | 272 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9629 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Nanjing Hengbei Chemicals Co., Ltd. | +86-25-58393656 | sales@hengbeichem.cn | China | 6854 | 58 |
View Lastest Price from 6-Bromobenzofuran manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-09-02 | 6-Bromobenzofuran
128851-73-0
|
US $1.00 / KG | 1KG | 98% | 1kg; 2kg；10kg; 100kg | Career Henan Chemical Co |
-
- 6-Bromobenzofuran
128851-73-0
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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