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4-Thiazolidinecarboxamide, 3-[(5-methyl-2-furanyl)carbonyl]-N-(5-methyl-2-thiazolyl)-

4-Thiazolidinecarboxamide, 3-[(5-methyl-2-furanyl)carbonyl]-N-(5-methyl-2-thiazolyl)- structure

CAS No.: 1281683-44-0

Chemical Name:: 4-Thiazolidinecarboxamide, 3-[(5-methyl-2-furanyl)carbonyl]-N-(5-methyl-2-thiazolyl)-

Synonyms: dCeMM4;3-(5-Methylfuran-2-carbonyl)-N-(5-methylthiazol-2-yl)thiazolidine-4-carboxamide;4-Thiazolidinecarboxamide, 3-[(5-methyl-2-furanyl)carbonyl]-N-(5-methyl-2-thiazolyl)-;N-(5-methyl-1,3-thiazol-2-yl)-3-(5-methylfuran-2-carbonyl)-1,3-thiazolidine-4-carboxamide

CBNumber:: CB88357557

Molecular Formula:: C14H15N3O3S2

Molecular Weight:: 337.42

MDL Number:

MOL File:: 1281683-44-0.mol

Last updated:2025-04-18 09:52:56

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4-Thiazolidinecarboxamide, 3-[(5-methyl-2-furanyl)carbonyl]-N-(5-methyl-2-thiazolyl)- Properties

Density	1.448±0.06 g/cm3(Predicted)
pka	7.50±0.70(Predicted)
form	Solid
color	Light yellow to yellow

4-Thiazolidinecarboxamide, 3-[(5-methyl-2-furanyl)carbonyl]-N-(5-methyl-2-thiazolyl)- Chemical Properties,Uses,Production

Uses

dCeMM4 (Compound 5) is a molecular glue degrader. dCeMM4 induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex[1].

References

[1] Mayor-Ruiz C, et al. Rational discovery of molecular glue degraders via scalable chemical profiling [published correction appears in Nat Chem Biol. 2021 Mar;17(3):361]. Nat Chem Biol. 2020;16(11):1199-1207. DOI:10.1038/s41589-020-0594-x

4-Thiazolidinecarboxamide, 3-[(5-methyl-2-furanyl)carbonyl]-N-(5-methyl-2-thiazolyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Thiazolidinecarboxamide, 3-[(5-methyl-2-furanyl)carbonyl]-N-(5-methyl-2-thiazolyl)- Suppliers

Global( 13)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	6771	55
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1608	58
Nantong Hi-Future Biotechnology Co., Ltd	18051384581	sales@chemhifuture.com	China	3210	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	62320	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24989	58
Henan Alpha Chemical Co., Ltd.	0371-55013243 15324716602	2853979810@qq.com	China	9963	58
Shanghai Tachizaki Biomedical Research Center	18014399201	sales@chemlab-tachizaki.com	China	2680	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Nantong HI-FUTURE Biology Co., Ltd.	58
Aladdin Scientific	58
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Jilin Province Woda Biotechnology Co., Ltd.	58
Nantong Hi-Future Biotechnology Co., Ltd	58
Bide Pharmatech Ltd.	58
TargetMol Chemicals Inc.	58
Henan Alpha Chemical Co., Ltd.	58
Shanghai Tachizaki Biomedical Research Center	58

4-Thiazolidinecarboxamide, 3-[(5-methyl-2-furanyl)carbonyl]-N-(5-methyl-2-thiazolyl)- dCeMM4 3-(5-Methylfuran-2-carbonyl)-N-(5-methylthiazol-2-yl)thiazolidine-4-carboxamide N-(5-methyl-1,3-thiazol-2-yl)-3-(5-methylfuran-2-carbonyl)-1,3-thiazolidine-4-carboxamide 1281683-44-0