Tetramethylene sulfoxide
- CAS No.
- 1600-44-8
- Chemical Name:
- Tetramethylene sulfoxide
- Synonyms
- TETRAHYDROTHIOPHENE 1-OXIDE;TETRAHYDROTHIOPHENE OXIDE;Thiophane oxide;thiophane1-oxide;Thiolane 1-oxide;Thiophane 1-oxide;thiophanemonoxide;1λ?-thiolan-1-one;Thiophane monoxide;Thiophene sulfoxide
- CBNumber:
- CB8853165
- Molecular Formula:
- C4H8OS
- Molecular Weight:
- 104.17
- MDL Number:
- MFCD00005477
- MOL File:
- 1600-44-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 235-237 °C(lit.) |
|---|---|
| Density | 1.158 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Storage temp. 2-8°C |
| form | Liquid |
| color | Clear colorless to yellow |
| Water Solubility | Fully miscible in water. |
| BRN | 105274 |
| Dielectric constant | 5.6(25℃) |
| InChI | 1S/C4H8OS/c5-6-3-1-2-4-6/h1-4H2 |
| InChIKey | ISXOBTBCNRIIQO-UHFFFAOYSA-N |
| SMILES | O=S1CCCC1 |
| CAS DataBase Reference | 1600-44-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | FL7PF5FLM2 |
| EPA Substance Registry System | Thiophene, tetrahydro-, 1-oxide (1600-44-8) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| PPE | Eyeshields, Gloves | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XN0830000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29041000 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,3500mg/kg (3500mg/kg),International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. Vol. 3, Pg. 41, 1961. | |||||||||
| NFPA 704 |
|
Tetramethylene sulfoxide price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T22403 | Tetrahydrothiophene 1-oxide 96% | 1600-44-8 | 25g | $119 | 2026-04-30 | Buy |
| TCI Chemical | T0146 | Tetramethylene Sulfoxide >95.0%(GC) | 1600-44-8 | 25g | $68 | 2026-04-30 | Buy |
| TCI Chemical | T0146 | Tetramethylene Sulfoxide >95.0%(GC) | 1600-44-8 | 500g | $597 | 2026-04-30 | Buy |
| Apolloscientific | OR916306 | Tetramethylene sulfoxide >99% | 1600-44-8 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR916306 | Tetramethylene sulfoxide >99% | 1600-44-8 | 5g | $24 | 2026-06-04 | Buy |
Tetramethylene sulfoxide Chemical Properties, Uses, Production
Chemical Properties
clear colorless to yellow liquid
Uses
In a comparative study of aromatic fluorodenitration with Potassium fluoride, in several dipolar aprotic solvents, a much faster reaction rate was observed with DMSO or tetramethylene sulfoxide than with the more commonly used Sulfolane.
Definition
ChEBI: Tetrahydrothiophene 1-oxide is a member of tetrahydrothiophenes.
Synthesis Reference(s)
Journal of the American Chemical Society, 63, p. 2939, 1941 DOI: 10.1021/ja01856a021
The Journal of Organic Chemistry, 50, p. 1787, 1985 DOI: 10.1021/jo00210a055
Synthetic Communications, 24, p. 2393, 1994 DOI: 10.1080/00397919408010545
Purification Methods
Shake the oxide with BaO for 4 days, then distil it from CaH2 under reduced pressure. [Beilstein 17 III/IV 36, 17/1 V 38.]
Tetramethylene sulfoxide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9978 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 45000 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
View Latest Price from Tetramethylene sulfoxide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-15 | Tetramethylene sulfoxide
1600-44-8
|
$1.50 | 1g | 99.0% Min | 100 Tons | Shaanxi Didu New Materials Co. Ltd |
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- Tetramethylene sulfoxide
1600-44-8
- $1.50
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd





