N-Methyl-D-aspartic acid
- CAS No.
- 6384-92-5
- Chemical Name:
- N-Methyl-D-aspartic acid
- Synonyms
- NMDA;n-methylaspartate;N-Me-D-Asp;H-D-MEASP-OH;N-ME-D-ASP-OH;H-N-Me-D-Asp-OH;H-D-MEASP-OH HCL;-D-aspartic acid;N-ME-D-ASP-OH HCL;N-Methyl-D-Asp-OH
- CBNumber:
- CB8854056
- Molecular Formula:
- C5H9NO4
- Molecular Weight:
- 147.13
- MDL Number:
- MFCD00004226
- MOL File:
- 6384-92-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| N-Methyl-D-aspartic acid ≥98% (TLC), solid | M3262 | 1g | $1120 |
| N-Methyl-D-aspartic Acid, Hydrate Excitatory amino acid neurotransmitter. | 454575 | 100mg | $348 |
| N-Methyl-D-aspartic Acid >98.0%(T) | M1360 | 100mg | $22 |
| N-Methyl-D-aspartic Acid >98.0%(T) | M1360 | 1g | $56 |
| NMDA ≥98% | 14581 | 50mg | $61 |
| More product size | |||
| Melting point | 187-192 °C |
|---|---|
| alpha | -28 º (c=1, HCl 6N) |
| Boiling point | 267.21°C (rough estimate) |
| Density | 1.4285 (rough estimate) |
| refractive index | -15 ° (C=2, H2O) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly) |
| pka | 2.21±0.23(Predicted) |
| form | solid |
| color | white |
| Water Solubility | slightly soluble |
| Sensitive | Hygroscopic |
| Merck | 14,6662 |
| BRN | 1724431 |
| LogP | 1.390 (est) |
| CAS DataBase Reference | 6384-92-5(CAS DataBase Reference) |
| FDA UNII | 1903B9Q6PI |
| UNSPSC Code | 12352209 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H319-H400-H372 |
| Precautionary statements | P273-P305+P351+P338 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | CI9457000 |
| F | 10 |
| HS Code | 29225090 |
N-Methyl-D-aspartic acid price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M3262 | N-Methyl-D-aspartic acid ≥98% (TLC), solid | 6384-92-5 | 1g | $1120 | 2025-07-31 | Buy |
| Sigma-Aldrich | 454575 | N-Methyl-D-aspartic Acid, Hydrate Excitatory amino acid neurotransmitter. | 6384-92-5 | 100mg | $348 | 2025-07-31 | Buy |
| TCI Chemical | M1360 | N-Methyl-D-aspartic Acid >98.0%(T) | 6384-92-5 | 100mg | $22 | 2025-07-31 | Buy |
| TCI Chemical | M1360 | N-Methyl-D-aspartic Acid >98.0%(T) | 6384-92-5 | 1g | $56 | 2025-07-31 | Buy |
| Cayman Chemical | 14581 | NMDA ≥98% | 6384-92-5 | 50mg | $61 | 2024-03-01 | Buy |
N-Methyl-D-aspartic acid Chemical Properties,Uses,Production
Chemical Properties
white to off-white crystalline powder
Uses
NMDA agonist
Uses
NMDA（N-Methyl-D-aspartic acid）is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.
Definition
ChEBI: An aspartic acid derivative having an N-methyl substituent and D-configuration.
General Description
N-Methyl-D-aspartic acid (NMDA) is an endogenously generated molecule in rat nervous system and endocrine glands. NMDA is present at low level (nmol/g) in the adenohypophysis, hypothalamus, brain, and testis. NMDA is derived from D-Asp by an S-adenosylmethionine-dependent enzyme also referred to as NMDA synthase.
Biological Activity
Prototypic NMDA receptor agonist. Also available as part of the Mixed NMDA Receptor Tocriset™ .
Biochem/physiol Actions
Excitotoxic amino acid. Prototypic agonist at the NMDA-type glutamate receptor that regulates ion channels; important in long-term potentiation, ischemia, and epilepsy.
storage
Room temperature
References
[1] watkins jc, jane de. the glutamate story. br j pharmacol. 2006 jan;147 suppl 1:s100-8.
[2] lafon-cazal m, pietri s, culcasi m, bockaert j. nmda-dependent superoxide production and neurotoxicity. nature. 1993 aug 5;364(6437):535-7.
N-Methyl-D-aspartic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8772 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-17392712697 | 1022@dideu.com | China | 3996 | 58 |
| Hebei Dangtong Import and export Co LTD | +86-86-4001020630 +8619831957301 | admin@hbdangtong.com | China | 1000 | 58 |
| Sichuan HongRi Pharma-Tech Co.,Ltd | +8617390183901 | cynthia@enlaibio.com | China | 1100 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Adachibio Inc. | +8108027837258 | sales@adachibio.com | Japan | 992 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21620 | 55 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
View Lastest Price from N-Methyl-D-aspartic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-13 | N-Me-D-Asp
6384-92-5
|
US $0.00-0.00 / kg | 1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | |
 |
2025-10-11 | N-Methyl-D-aspartic acid ( NMDA ) 99%
6384-92-5
|
US $1.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-09-26 | N-Methyl-D-aspartic acid
6384-92-5
|
US $3288.00-2680.00 / kg | 1kg | 99% | 1000kg | Hebei Dangtong Import and export Co LTD |
-
- N-Me-D-Asp
6384-92-5
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- N-Methyl-D-aspartic acid ( NMDA ) 99%
6384-92-5
- US $1.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- N-Methyl-D-aspartic acid
6384-92-5
- US $3288.00-2680.00 / kg
- 99%
- Hebei Dangtong Import and export Co LTD
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