ChemicalBook >> CAS DataBase List >>Melitracen hydrochloride

Melitracen hydrochloride

Melitracen hydrochloride structure

CAS No.: 10563-70-9

Chemical Name:: Melitracen hydrochloride

Synonyms: Adaptol;Thymeol;U-24973A;Melixeran;Trausabun;Adaptol-d6;Thymeol-d6;Melixeran-d6;Trausabun-d6;Melitracene-d6

CBNumber:: CB8874744

Molecular Formula:: C21H26ClN

Molecular Weight:: 327.89084

MDL Number:: MFCD00242905

MOL File:: 10563-70-9.mol

MSDS File:: SDS

Last updated:2026-02-28 13:03:53

Product description	Number	Pack Size	Price
Melitracen hydrochloride ≥98% (HPLC)	SML2600	10 mg	$85
Melitracen hydrochloride ≥98% (HPLC)	SML2600	50 mg	$276
Melitracen hydrochloride British Pharmacopoeia (BP) Reference Standard	BP1151	25 mg	$257
Melitracen-d6 Hydrochloride	015892	1mg	$446
MelitracenHydrochloride	M215500	10mg	$155
More product size

Request For Quotation

Melitracen hydrochloride Properties

Melting point	245-248°C
storage temp.	Sealed in dry,Room Temperature
solubility	Soluble in DMSO
form	Solid
color	White to Off-White
Water Solubility	H2O: 2mg/mL, clear (warmed)
InChI	InChI=1S/C21H25N.ClH/c1-21(2)19-13-7-5-10-17(19)16(12-9-15-22(3)4)18-11-6-8-14-20(18)21;/h5-8,10-14H,9,15H2,1-4H3;1H
InChIKey	RADLXCPDUXFGFF-UHFFFAOYSA-N
SMILES	C12C=CC=CC=1C(C1C=CC=CC=1/C/2=C\CCN(C)C)(C)C.Cl
CAS DataBase Reference	10563-70-9(CAS DataBase Reference)
FDA UNII	J3448GKP5W
UNSPSC Code	41116107
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
WGK Germany	WGK 3
Storage Class	6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects
Hazard Classifications	Acute Tox. 3 Oral
Toxicity	LD50 i.v. in mice: 52 mg/kg (Petersen)

Melitracen hydrochloride price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML2600	Melitracen hydrochloride ≥98% (HPLC)	10563-70-9	10 mg	$85	2025-07-31	Buy
Sigma-Aldrich	SML2600	Melitracen hydrochloride ≥98% (HPLC)	10563-70-9	50 mg	$276	2025-07-31	Buy
Sigma-Aldrich	BP1151	Melitracen hydrochloride British Pharmacopoeia (BP) Reference Standard	10563-70-9	25 mg	$257	2025-07-31	Buy
Usbiological	015892	Melitracen-d6 Hydrochloride	10563-70-9	1mg	$446	2021-12-16	Buy
TRC	M215500	MelitracenHydrochloride	10563-70-9	10mg	$155	2021-12-16	Buy

Product number	Packaging	Price	Buy
SML2600	10 mg	$85	Buy
SML2600	50 mg	$276	Buy
BP1151	25 mg	$257	Buy
015892	1mg	$446	Buy
M215500	10mg	$155	Buy

Melitracen hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Originator

Trausabun,Lusofarma,W. Germany,1965

Uses

Antidepressant

Definition

ChEBI: Melitracen hydrochloride is a member of anthracenes.

Manufacturing Process

24 g of 2-o-benzoylphenylpropanol-2 (MP 116°C) were dissolved in 250 ml of anhydrous ether and the resulting solution was added dropwise while stirring to a suspension of 0.22 mol of dimethylaminopropylmagnesium chloride in 100 ml of ether. The reaction mixture was refluxed for one hour on a steam bath, and water and dilute hydrochloric acid were added until the reaction was pH 4-5. The aqueous phase was separated and 60 ml of concentrated aqueous ammonia were added. The mixture was extracted with ether, and the ether phase was separated, dried and evaporated in a steam bath. The residue was dissolved in hot petroleum ether and the solution left standing to cool for some time, whereupon 4-dimethylamino-1-phenyl-1-[2-(2-hydroxy-2- propyl)phenyl]-butanol-1 crystallized out as white crystals which were sucked off. After drying they melted at 88°C to 90°C.
10 g of this compound were cautiously dissolved in 50 ml of concentrated sulfuric acid under cooling and the mixture was kept at room temperature for 24 hours, whereupon the reaction mixture was poured into 200 g of finely crushed ice, and concentrated aqueous ammonia was added to about pH 9, whereupon the oil which separated out was extracted with ether. The ether phase was separated, dried and the ether evaporated on a steam bath. The residue was dissolved in 20 ml of acetone and the solution neutralized with a solution of dry hydrogen chloride in ether. The white crystals of 9-γdimethylaminopropylidene-10,10-dimethyl-9,10-dihydroanthracene hydrochloride which separated out was filtered off and dried. Yield 9 g. MP 245°C to 247°C.

Therapeutic Function

Antidepressant

Biological Activity

Melitracen is a tricyclic antidepressant (TCA) th at likely exerts its in vivo efficacy similarly as imipramine and amitriptyline by inhibiting serotonin-norepinephrine reuptake.

Melitracen hydrochloride Preparation Products And Raw materials

Raw materials

Magnesium Sulfuric acid Hydrochloric acid 3-Chloro-1-(N,N-dimethyl)propylamine

Preparation Products

Melitracen hydrochloride Suppliers

Global( 188)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Moxin Chemicals	+86-17320513646 +8617320513646	anna@molcoo.com	China	10000	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21595	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58
Shandong ruiyue Biological Technology Co.，Ltd.	008615066100122（Lily wechat）	513075341@qq.com	CHINA	52	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Henan Bao Enluo International TradeCo.，LTD	58
Moxin Chemicals	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Shandong ruiyue Biological Technology Co.，Ltd.	58
Xiamen AmoyChem Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58

View Lastest Price from Melitracen hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-02-28	Melitracen hydrochloride 10563-70-9	US $39.00-89.00 / mg		99.99%	10g	TargetMol Chemicals Inc.
2026-02-27	Melitracen hydrochloride 10563-70-9	US $0.00-0.00 / Kg/Bag	100g	99%min	1000G	WUHAN FORTUNA CHEMICAL CO., LTD
2025-12-16	Melitracen Hydrochloride 10563-70-9	US $0.00-0.00 / mg	10mg	99%+ HPLC	1000	Moxin Chemicals

Melitracen hydrochloride
10563-70-9
US $39.00-89.00 / mg
99.99%
TargetMol Chemicals Inc.

Melitracen hydrochloride
10563-70-9
US $0.00-0.00 / Kg/Bag
99%min
WUHAN FORTUNA CHEMICAL CO., LTD

Melitracen Hydrochloride
10563-70-9
US $0.00-0.00 / mg
99%+ HPLC
Moxin Chemicals

Melitracen hydrochloride Spectrum

Melitracen hydrochloride(10563-70-9)¹HNMR

10563-70-9(Melitracen hydrochloride )Related Search:

1-AdaMantanethylaMine Melitracen Topotecan hydrochloride Isopropylamine ETHANE

Dimethyl ether Dimethyl fumarate Dimethyl sulfate Dimethyl carbonate N,N-Dimethylformamide

Diisopropylammonium dichloroacetate Dacthal 3-[10,10-bis(trideuteriomethyl)anthracen-9-ylidene]-N,N-dimethylpropan-1-amine:hydrochloride Dimethyl sulfoxide (-)-2-[METHYLAMINO]-1-PHENYLPROPANE

Sibutramine hydrochloride Tramadol hydrochloride D/L-AMPHETAMINE HYDROCHLORIDE

1of4

Melitracen Hydrochlorlde MELITRACEN HYDROCHLORLD 1-Propanamine, 3-(10,10-dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-, hydrochloride MELITRACEN HYDROCHLORID 3-[10,10-dimethyl-9(10H)-anthrylidene]-N,N-dimethylpropylamine hydrochloride Melitracen hydrochloride 3-(10,10-Dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-1-propanamine Hydrochloride 9-(3-Dimethylaminopropylidene)-10,10-dimethyl-9,10-dihydroanthracene Hydrochloride Adaptol Melixeran Thymeol Trausabun U-24973A 3-(10,10-Dimethyl-d6)-9(10H)-anthracenylidene)-N,N-dimethyl-1-propanamine Hydrochloride 9-(3-Dimethylaminopropylidene)-10,10-(dimethyl-d6)-9,10-dihydroanthracene Hydrochloride Adaptol-d6 Melitracen-d6 Hydrochloride Melitracene-d6 Melixeran-d6 Thymeol-d6 Trausabun-d6 2-Melitracen hydrochloride 1-PropanaMine,3-(10,10-diMethyl-9(10H)-anthracenylidene)-N,N-diMethyl-, hydrochloride (1:1) Hydrochloride Melitracen Melitracen hydrochloride ###Melitracen 3-(10,10-dimethylanthracen-9(10H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride HYDROGEN MELITRACEN CHLORIDE 3-(10,10-dimethyl-9-anthracenylidene)-N,N-dimethyl-1-propanamine Melitracen Impurity C Thymeol hydrochloride Melitracen hydrochloride USP/EP/BP Fenoterol-D6 Acetate in Methanol Melitracen Hydrochloride in Methanol Melitracen hydrochloride, 10 mM in DMSO 10563-70-9 C21H20D6ClN C21H26NCl Isotope Labelled Compounds Antidepressant Isotope Labeled Compounds Amines Aromatics Intermediates & Fine Chemicals Pharmaceuticals