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ChemicalBook >> CAS DataBase List >>[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide

[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide

[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide Structure
[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide structure
CAS No.
6901-13-9
Chemical Name:
[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide
Synonyms
Colchicine EP Impurity C;beta-lumi;lumicolchicine.;β-Lumi(-)-Colchicine;b-Lumi (-)-Colchicine;(-)-beta-Lumicolchicine;N-[(7S,7bR,10aS)-1,2,3,9-Tetrametho;β-Lumi (-)-colchicine, CAS 6901-13-9;β-Lumi (-)-Colchicine/β-Lumicolchicine;Colchicine EP Impurity C/β-Lumicolchicine
CBNumber:
CB8895398
Molecular Formula:
C22H25NO6
Molecular Weight:
399.437
MDL Number:
MFCD00151111
MOL File:
6901-13-9.mol
MSDS File:
SDS
Last updated:2026-05-28 04:28:45
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[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide Properties

Melting point 177-180°C
Density 1.30±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility Chloroform (Slightly), Methanol (Sparingly)
form Solid
color Off-White to Pale Orange
Stability Light Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-L474300-10MG beta-Lumi (-)-Colchicine >95%(HPLC) 6901-13-9 10mg $254 2026-06-03 Buy
TRC TRC-L474300-100MG beta-Lumi (-)-Colchicine >95%(HPLC) 6901-13-9 100mg $1911 2026-06-03 Buy
Usbiological 015712 β-Lumi (-)-Colchicine ~90% 6901-13-9 10mg $496 2026-06-03 Buy
Biosynth FL161175 (-)-beta-Lumicolchicine 6901-13-9 1mg $900 2026-06-04 Buy
Biosynth FL161175 (-)-beta-Lumicolchicine 6901-13-9 10mg $900 2026-06-04 Buy
Product number Packaging Price Buy
TRC-L474300-10MG 10mg $254 Buy
TRC-L474300-100MG 100mg $1911 Buy
015712 10mg $496 Buy
FL161175 1mg $900 Buy
FL161175 10mg $900 Buy

[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide Chemical Properties, Uses, Production

Description

This alkaloid has been isolated from a number of plants including Colchicum kesselringii, C. luteum Baker, Merendera jolanta E. Czerniak, M. raddeana Rgl.and M. robusta Bge. It forms colourless crystals from CHC13-Et20. It is possible that this base may be an artifact formed during the isolation process.

Chemical Properties

Pale Yellow Solid

Uses

An analog of Colchicine (C640000), β-lumicolchicine, does not bind tubulin or disrupt microtubules. A GABAA receptor chloride channel.

Definition

ChEBI: LSM-4236 is a carbotricyclic compound, a member of acetamides and an alkaloid.

References

Santavy, Collect. Czech. Chem. Commun., 16,665 (1951)
Santavy, Pharm. Zent., 96, 307 (1957)
Yusupov, Sadykov, Tr. Nauch. Tashkent. Gos. Univ., 203, 3, 15 (1962)
YUSUpOY, SadykoY, J. Gen. Chem. USSR, 34, 1672 (1964)
Yusupov, Sadykov, Tr. Nauch. Tashkent. Gos. Univ., 286,11,56 (1966)
Chommedov, Yusupov, Sadykov, Khim. Prir. Soedin., 6, 82, 275 (1970)
Trozyan, Yusupov, Sadykov, ibid, 7,541 (1971)
Santavy, Tr. Nauchi. Tashkent, 11 (1972)

[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide synthesis

64-86-8
6901-13-9
Synthesis of [7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide from Colchicine

[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

Acetamide, N,N'-[(7S,7bR,8aS,8bS,9aR,10S,16cS,16dR,16eR,16fS)-5,6,7,7b,8,8a,8b,9,9a,10,11,12,16c,16d,16e,16f-hexadecahydro-1,2,3,8a,8b,14,15,16-octamethoxy-8,9-dioxobisbenzo[3',4']cyclohepta[1',2':3,4]cyclobuta[1,2-c:1',2'-c']cyclobuta[1,2-a:4,3-a']dicyclopentene-7,10-diyl]bis- GAMMA-LUMICOLCHICINE

[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide Suppliers

Global Suppliers ( 62)
Supplier Tel Email Country ProdList Advantage
Changzhou Zeyuan Pharmaceutical Technology Co., Ltd 15090501328 2051576189@qq.com China 132 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 5000 50
Qingdao Kingway Pharmtech Co., Ltd. 0532-87118899 sales@kingwaypharm.com China 119 56
Hubei XinyuanShun Chemical Co., Ltd. 13971561712, 13995564702, 027-50664929 hbeixys2001@163.com China 3110 55
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shenzhen SUNGENING Bio-Medical Co., Ltd. 0755-28967200 13631290199 wxf@sungening.com China 9609 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
Shenzhen Botel Biotechnology Co. Ltd. 13316949107 13316968096 1979313431@qq.com China 9619 58
Supplier Advantage
Changzhou Zeyuan Pharmaceutical Technology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
S.Z. PhyStandard Bio-Tech. Co., Ltd. 50
Qingdao Kingway Pharmtech Co., Ltd. 56
Hubei XinyuanShun Chemical Co., Ltd. 55
Quality Control Solutions Ltd. 56
Shenzhen SUNGENING Bio-Medical Co., Ltd. 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
Shenzhen Botel Biotechnology Co. Ltd. 58

6901-13-9 ([7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide) Related Search:

Colchicine GAMMA-LUMICOLCHICINE Acetamide, N,N'-[(7S,7bR,8aS,8bS,9aR,10S,16cS,16dR,16eR,16fS)-5,6,7,7b,8,8a,8b,9,9a,10,11,12,16c,16d,16e,16f-hexadecahydro-1,2,3,8a,8b,14,15,16-octamethoxy-8,9-dioxobisbenzo[3',4']cyclohepta[1',2':3,4]cyclobuta[1,2-c:1',2'-c']cyclobuta[1,2-a:4,3-a']dicyclopentene-7,10-diyl]bis- (2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino- 6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12 -trione 7-Monodemethyl Minocycline
4-Epiminocycline

1of2

[7S-(7alpha,7bbeta,10abeta)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide Colchicine Impurity 3（Colchicine EP Impurity C） N-[(7S)-5,6,7,7bβ,8,10aβ-Hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetamide N-[(7S,7bR,10aS)-5,6,7,7b,8,10a-Hexahydro-1,2,3,9-tetraMethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetaMide N-[(7S,7bR,10aS)-1,2,3,9-Tetrametho Acetamide, N-[(7S,7bR,10aS)-5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]- N-((7S,7bR,10aS)-1,2,3,9-tetramethoxy-8-oxo-5,6,7,7b,8,10a-hexahydrobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c][7]annulen-7-yl)acetamide β-Lumi(-)-Colchicine N-[(7S,7bR,10aS)-1,2,3,9-Tetramethoxy-8-oxo-5,6,7,7b,8,10a-hexahydrobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetamide (β-Lumicolchicine) lumicolchicine. beta-lumi β-Lumi (-)-Colchicine/β-Lumicolchicine N-[(7S,7bR,10aS)-1,2,3,9-Tetramethoxy-8-oxo-5,6,7,7b,8,10a-hexahydrobenzo[a]cyclopenta[3,4]cyclobuta [7S-(7α,7bβ,10aβ)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide (-)-beta-Lumicolchicine β-Lumi (-)-colchicine, CAS 6901-13-9 Colchicine EP Impurity C/β-Lumicolchicine N-[(7S,7bR,10aS)-1,2,3,9-Tetramethoxy-8-oxo-5,6,7,7b,8,10a-hexahydrobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetamide (beta-Lumicolchicine) Colchicine EP Impurity C b-Lumi (-)-Colchicine 6901-13-9 Amines Chiral Reagents Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Alkaloids