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(9R)-6'-methoxycinchonan-9-ol

CAS No.
572-59-8
Chemical Name:
(9R)-6'-methoxycinchonan-9-ol
Synonyms
Epiquinidine;9-Epiquinidine;(9R)-;Epiquindine;(9R)-6'-methoxycinchonan-9-ol;(8R,9R)-6'-Methoxycinchonan-9-ol;Cinchonan-9-ol, 6'-methoxy-, (9R)-;(R)-(6-methoxy-4-quinolyl)-[(2R,4S,5R)-5-vinylquinuclidin-2-yl]methanol;(R)-[(4S,5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol
CBNumber:
CB8939382
Molecular Formula:
C20H24N2O2
Molecular Weight:
324.42
MDL Number:
MFCD19686977
MOL File:
572-59-8.mol
MSDS File:
SDS
Last updated:2026-05-28 03:52:25

(9R)-6'-methoxycinchonan-9-ol Properties

Melting point 111-113°
alpha D25 +107.8° (c = 1.02 in ethanol)
Boiling point 462.75°C (rough estimate)
Density 1.1294 (rough estimate)
refractive index 1.5700 (estimate)
storage temp. 2-8°C
form Solid-Liquid Mixture
pka 12.80±0.20(Predicted)
color White to off-white
FDA UNII RN974X9U97

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H317-H334
Precautionary statements  P261-P280-P342+P311
Hazard Codes  Xn
Risk Statements  22-42/43
Safety Statements  22-36/37-45

(9R)-6'-methoxycinchonan-9-ol price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0100827 Epiquinidine ≥98% 572-59-8 10mg $980 2026-06-04 Buy
aablocks AA00EF1V (R)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol >98% 572-59-8 5mg $713 2026-05-28 Buy
aablocks AA00EF1V (R)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol 98% 572-59-8 10mg $784 2026-05-28 Buy
ACHEMBLOCK AD269056 Epiquinidine 95% 572-59-8 10MG $1370 2026-05-27 Buy
ACHEMBLOCK AD269056 Epiquinidine 95% 572-59-8 25MG $2740 2026-05-27 Buy
Product number Packaging Price Buy
CS-0100827 10mg $980 Buy
AA00EF1V 5mg $713 Buy
AA00EF1V 10mg $784 Buy
AD269056 10MG $1370 Buy
AD269056 25MG $2740 Buy

(9R)-6'-methoxycinchonan-9-ol Chemical Properties, Uses, Production

Description

This alkaloid is stereoisomeric with epiQuinine and occurs in 'Quinoidine', the mixture of amorphous bases left after extraction of the four primary alkaloids of Cinchona bark. It crystallizes in colourless leaflets from Et20 and is fluorescent in dilute H2S04, It is dextrorotatory with [α]19D + 102.4° (c 0.8648, EtOH) and furnishes a dihydrochloride, m.p. 195-6°C (dec.); [α]20D + 45.5° (c 0.8012, EtOH); a hydrobromide, m.p. 240°C; thiocyanate, m.p. 193°C; [α]20D + 44.5° (H20) and the dibenzoyl-(+)-tartrate, m.p. 167°C; [α]201D + 3.7° (c 0.8068, EtOH-CHCI 3 ). Catalytic hydrogenation with Pd gives the dihydro derivative, m.p. 122°C; [α]22D + 73.1° (c 0.766, EtOH).

Uses

The 9-epimer of Quinidine (Q685000). Antimalarial.

References

Thron, Dirscherl., Annalen, 521,48 (1935)

(9R)-6'-methoxycinchonan-9-ol Preparation Products And Raw materials

Raw materials

Preparation Products

(9R)-6'-methoxycinchonan-9-ol Suppliers

Global Suppliers ( 30)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55
Creative Peptides info@creative-peptides.com United States 6083 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Shanghai Elestone Pharmaceutical Technology Co., Ltd. 021-36680027/1762825045 sales2@elestone.com.cn China 296 58
Shanghai Anyinuo Biomedical Technology Co., Ltd. 021-34625901 420970979@qq.com China 5982 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
Hefei Hirisun Pharmatech Co., Ltd +8615056975894 shawn@hirisunpharm.com CHINA 9897 58
Epiquindine (9R)-6'-methoxycinchonan-9-ol (8R,9R)-6'-Methoxycinchonan-9-ol (R)-(6-methoxy-4-quinolyl)-[(2R,4S,5R)-5-vinylquinuclidin-2-yl]methanol (R)-[(4S,5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol (9R)- Cinchonan-9-ol, 6'-methoxy-, (9R)- 9-Epiquinidine Epiquinidine 572-59-8 Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals