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RO 5126946

RO 5126946 Structure
RO 5126946 structure
CAS No.
1137233-79-4
Chemical Name:
RO 5126946
Synonyms
RO 5126946;Benzamide, N-[(1S,3R)-3-[4-(aminosulfonyl)phenyl]-2,2-dimethylcyclopropyl]-5-chloro-2-methoxy-
CBNumber:
CB89635463
Molecular Formula:
C19H21ClN2O4S
Molecular Weight:
408.9
MDL Number:
MOL File:
1137233-79-4.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
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RO 5126946 Properties

Density 1.40±0.1 g/cm3(Predicted)
pka 10.19±0.10(Predicted)

RO 5126946 Chemical Properties, Uses, Production

Description

RO5126946 is a Novel α7 nicotinic acetylcholine receptor-positive allosteric modulator. RO5126946 allosterically modulates α7nAChR activity. RO5126946 increased acetylcholine-evoked peak current and delayed current decay but did not affect the recovery of α7nAChRs from desensitization. In addition, RO5126946's effects were absent when nicotine-evoked currents were completely blocked by coapplication of the α7nAChR-selective antagonist methyl-lycaconitine.

RO 5126946 Preparation Products And Raw materials

Raw materials

Preparation Products

RO 5126946 Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from RO 5126946 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
RO5126946 pictures 2026-04-20 RO5126946
1137233-79-4
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • RO5126946 pictures
  • RO5126946
    1137233-79-4
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.
RO 5126946 Benzamide, N-[(1S,3R)-3-[4-(aminosulfonyl)phenyl]-2,2-dimethylcyclopropyl]-5-chloro-2-methoxy- 1137233-79-4