ChemicalBook >> CAS DataBase List >>Baxdrostat
Baxdrostat
- CAS No.
- 1428652-17-8
- Chemical Name:
- Baxdrostat
- Synonyms
- RG-7641;CIN-107;RO-6836191;Baxdrostat;Baxdrostat, 10 mM in DMSO;(R)-N-(4-(1-Methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide;Propanamide, N-[(8R)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl]-;(+)-(R)-N-(4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide
- CBNumber:
- CB89763124
- Molecular Formula:
- C22H25N3O2
- Molecular Weight:
- 363.45
- MDL Number:
- MOL File:
- 1428652-17-8.mol
Last updated:2026-01-26 13:56:28
| Boiling point | 697.6±55.0 °C(Predicted) |
|---|---|
| Density | 1.24±0.1 g/cm3(Predicted) |
| solubility | DMSO : 250 mg/mL (687.85 mM; Need ultrasonic) |
| form | Solid |
| pka | 15.05±0.20(Predicted) |
| color | Off-white to light yellow |
| InChI | InChI=1S/C22H25N3O2/c1-3-21(26)24-19-6-4-5-16-17(12-23-13-18(16)19)14-7-9-20-15(11-14)8-10-22(27)25(20)2/h7,9,11-13,19H,3-6,8,10H2,1-2H3,(H,24,26)/t19-/m1/s1 |
| InChIKey | VDEUDSRUMNAXJG-LJQANCHMSA-N |
| SMILES | C(N[C@H]1C2=C(CCC1)C(C1C=CC3=C(C=1)CCC(=O)N3C)=CN=C2)(=O)CC |
| FDA UNII | NF3P9Z8J5Y |
Baxdrostat Chemical Properties,Uses,Production
Uses
Baxdrostat is a novel aldosterone synthase Inhibitor for treatment resistant hypertension and systemic Hypertension.
Mode of action
The mechanism of action of baxdrostat as an aldosterone synthase inhibitor demonstrates the inextricable linkage between sodium and blood pressure regulation. Baxdrostat significantly decreases aldosterone in plasma and urine, while increasing plasma renin as a physiological compensatory change.
Baxdrostat Preparation Products And Raw materials
Raw materials
Preparation Products
Baxdrostat Suppliers
Global( 50)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 11727 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Hefei TianRui Pharmaceutical Chemical Co., Ltd. | +86-0551-68665055 +86-+86-18616906106 | sales@trywchem.com | China | 186 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Chengdu Yunyidian Biological Technology Co.,Ltd | 17621298782 | sales@cdyunyidian.com | China | 257 | 58 |
| Afflon Pharmaceutical (Sichuan) Co., Ltd. | 17336178085 | 1684779048@qq.com | China | 2057 | 58 |
| CAREBIO PHARMA | 18501057619 18501057619; | jackyfan@rebornpharma.com | China | 275 | 58 |
| Hefei TianRui Pharmaceutical Chemistry Co., Ltd. | 0551-68933033 13956024211 | trchem@163.com | China | 98 | 58 |
| Bayee Biotech (Anqing) Co., Ltd. | 0556-5032306 18917961636 | wtx@bayeebio.com | China | 229 | 61 |
View Lastest Price from Baxdrostat manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-26 | Baxdrostat
1428652-17-8
|
US $68.00-263.00 / mg | 99.80% | 10g | TargetMol Chemicals Inc. |
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- Baxdrostat
1428652-17-8
- US $68.00-263.00 / mg
- 99.80%
- TargetMol Chemicals Inc.
Propanamide, N-[(8R)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl]-
Baxdrostat
(R)-N-(4-(1-Methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide
Baxdrostat, 10 mM in DMSO
RG-7641
RO-6836191
CIN-107
(+)-(R)-N-(4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide
1428652-17-8
