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ChemicalBook >> CAS DataBase List >>Benzeneethanamine, 3,4-difluoro- (9CI)

Benzeneethanamine, 3,4-difluoro- (9CI)

Benzeneethanamine, 3,4-difluoro- (9CI) Structure
Benzeneethanamine, 3,4-difluoro- (9CI) structure
CAS No.
220362-31-2
Chemical Name:
Benzeneethanamine, 3,4-difluoro- (9CI)
Synonyms
2-(3,4-fluorophenyl)ethylamine;2-(3,4-fluorophenyl)ethanamine;3,4-Difluoro-benzeneethanaMine;2-(3,4-Difluorophenyl)ethylamine;2-(3,4-Difluorophenyl)ethanamine;BenzeneethanaMine, 3,4-difluoro-;Benzeneethanamine, 3,4-difluoro- (9CI);BENZENEETHANAMINE,3,4-DIFLUORO- (CAS NO.220362-31-2)
CBNumber:
CB91050720
Molecular Formula:
C8H9F2N
Molecular Weight:
157.16
MDL Number:
MFCD01529877
MOL File:
220362-31-2.mol
MSDS File:
SDS
Last updated:2026-05-28 03:43:28
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Benzeneethanamine, 3,4-difluoro- (9CI) Properties

Boiling point 203℃
Density 1.169
Flash point 91℃
storage temp. 2-8°C(protect from light)
solubility Acetonitrile (Slightly), Chloroform (Slightly)
form Oil
pka 9.25±0.10(Predicted)
color Colourless

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Corrosion (GHS05)
GHS07,GHS05
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P264-P270-P301+P312-P330-P501-P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501

Benzeneethanamine, 3,4-difluoro- (9CI) price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L300233 2-(3,4-DIFLUOROPHENYL)ETHANAMINE AldrichCPR 220362-31-2 50MG $159 2022-05-15 Buy
TRC TRC-D451245-500MG 2-(3,4-Difluorophenyl)ethanamine 220362-31-2 500mg $205 2026-06-03 Buy
Biosynth FD97834 2-(3,4-Difluorophenyl)ethanamine 220362-31-2 250mg $250 2026-06-04 Buy
Biosynth FD97834 2-(3,4-Difluorophenyl)ethanamine 220362-31-2 500mg $385 2026-06-04 Buy
Biosynth FD97834 2-(3,4-Difluorophenyl)ethanamine 220362-31-2 1000mg $630 2026-06-04 Buy
Product number Packaging Price Buy
L300233 50MG $159 Buy
TRC-D451245-500MG 500mg $205 Buy
FD97834 250mg $250 Buy
FD97834 500mg $385 Buy
FD97834 1000mg $630 Buy

Benzeneethanamine, 3,4-difluoro- (9CI) Chemical Properties, Uses, Production

Synthesis

1,2-difluoro-4-[(E)-2-nitroethenyl]benzene

1025692-47-0

Benzeneethanamine, 3,4-difluoro- (9CI)

220362-31-2

Synthesis of intermediate 2-(3,4-difluorophenyl)ethylamine (I-49b): the preparation and post-treatment steps were carried out with reference to the preparation of intermediate I-15b. The specific operation was as follows: E-1,2-difluoro-4-(2-nitrovinyl)benzene (I-49a, 5 g, 27.027 mmol) was dissolved in anhydrous THF (81 mL), and LiBH4 (2.35 g, 108.1081 mmol) and chlorotrimethylsilane (27.63 mL, 216.216 mmol) were added sequentially at 0 °C. The reaction mixture was stirred at room temperature for 3 days. Upon completion of the reaction, 4.2 g of the target product was obtained by post-processing in 100% yield. The product was characterized by 1H NMR (DMSO, 300 MHz): δ 8.7 (broad peak, 2H), 7.5-7.3 (multiple peaks, 2H), 7.2-7.0 (multiple peaks, 1H), 3.0-2.8 (multiple peaks, 4H).LCMS analysis showed a purity of 98.87%, m/z = 158.1 (M + 1).

References

[1] Patent: US2014/45872, 2014, A1. Location in patent: Paragraph 0814
[2] Patent: WO2008/39882, 2008, A1. Location in patent: Page/Page column 191

Benzeneethanamine, 3,4-difluoro- (9CI) synthesis

1025692-47-0
220362-31-2
Synthesis of Benzeneethanamine, 3,4-difluoro- (9CI) from 1,2-difluoro-4-[(E)-2-nitroethenyl]benzene

Benzeneethanamine, 3,4-difluoro- (9CI) Preparation Products And Raw materials

Raw materials

1,2-difluoro-4-[(E)-2-nitroethenyl]benzene Tetrahydrofuran Lithium borohydride Chlorotrimethylsilane

Preparation Products

Benzeneethanamine, 3,4-difluoro- (9CI) Suppliers

Global Suppliers ( 44)
Supplier Tel Email Country ProdList Advantage
Changzhou Xiaqing Technological Co., Ltd. 88783621 15961106108 john.chiang@xialichem.com China 144 70
Shanghai Yolne Chemical Co., Ltd. 021-62960152 934678158@qq.com China 9886 55
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9848 55
DebyeTec.com Inc. 18086626237 18086626237 2693528373@qq.com China 2934 56
Zhengzhou Alfachem Co., Ltd. 0371-53765687 18937137882 3969243885@qq.com China 7731 55
Shanghai YuanYe Biotechnology Co., Ltd. 18916372613 yanzihan@shyuanye.com China 87240 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-58859352 15955137747 sales01@aikonchem.com China 16021 58
Yujinpharma(Tianjin) Technology Co.,Ltd. 13370351217 kungfu1217@1 kungfu1217@163.com China 7986 58
Cool Pharm, Ltd 021-58581007 18019463053 sales@coolpharm.com China 9999 58
Supplier Advantage
Changzhou Xiaqing Technological Co., Ltd. 70
Shanghai Yolne Chemical Co., Ltd. 55
Amatek Scientific Co. Ltd. 55
DebyeTec.com Inc. 56
Zhengzhou Alfachem Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Aikon International Limited 58
Yujinpharma(Tianjin) Technology Co.,Ltd. 58
Cool Pharm, Ltd 58

View Latest Price from Benzeneethanamine, 3,4-difluoro- (9CI) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Benzeneethanamine, 3,4-difluoro- (9CI) pictures 2024-10-22 Benzeneethanamine, 3,4-difluoro- (9CI)
220362-31-2
 $1.00 1g 85.0-99.8% 20 tons Career Henan Chemica Co

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Benzeneethanamine, 3,4-difluoro- (9CI) BenzeneethanaMine, 3,4-difluoro- 2-(3,4-Difluorophenyl)ethanamine 2-(3,4-Difluorophenyl)ethylamine 3,4-Difluoro-benzeneethanaMine BENZENEETHANAMINE,3,4-DIFLUORO- (CAS NO.220362-31-2) 2-(3,4-fluorophenyl)ethanamine 2-(3,4-fluorophenyl)ethylamine 220362-31-2 22362-31-2 HALIDE