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Benzeneethanamine, 3,4-difluoro- (9CI)

Benzeneethanamine, 3,4-difluoro- (9CI) structure

CAS No.: 220362-31-2

Chemical Name:: Benzeneethanamine, 3,4-difluoro- (9CI)

Synonyms: 2-(3,4-fluorophenyl)ethylamine;2-(3,4-fluorophenyl)ethanamine;3,4-Difluoro-benzeneethanaMine;2-(3,4-Difluorophenyl)ethylamine;2-(3,4-Difluorophenyl)ethanamine;BenzeneethanaMine, 3,4-difluoro-;Benzeneethanamine, 3,4-difluoro- (9CI);BENZENEETHANAMINE,3,4-DIFLUORO- (CAS NO.220362-31-2)

CBNumber:: CB91050720

Molecular Formula:: C8H9F2N

Molecular Weight:: 157.16

MDL Number:: MFCD01529877

MOL File:: 220362-31-2.mol

MSDS File:: SDS

Last updated:2026-05-28 03:43:28

Product description	Number	Pack Size	Price
2-(3,4-DIFLUOROPHENYL)ETHANAMINE AldrichCPR	L300233	50MG	$159
2-(3,4-Difluorophenyl)ethanamine	TRC-D451245-500MG	500mg	$205
2-(3,4-Difluorophenyl)ethanamine	FD97834	250mg	$250
2-(3,4-Difluorophenyl)ethanamine	FD97834	500mg	$385
2-(3,4-Difluorophenyl)ethanamine	FD97834	1000mg	$630

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Benzeneethanamine, 3,4-difluoro- (9CI) Properties

Boiling point	203℃
Density	1.169
Flash point	91℃
storage temp.	2-8°C(protect from light)
solubility	Acetonitrile (Slightly), Chloroform (Slightly)
form	Oil
pka	9.25±0.10(Predicted)
color	Colourless

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS05
Signal word	Danger
Hazard statements	H302-H314
Precautionary statements	P264-P270-P301+P312-P330-P501-P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501

Benzeneethanamine, 3,4-difluoro- (9CI) price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	L300233	2-(3,4-DIFLUOROPHENYL)ETHANAMINE AldrichCPR	220362-31-2	50MG	$159	2022-05-15	Buy
TRC	TRC-D451245-500MG	2-(3,4-Difluorophenyl)ethanamine	220362-31-2	500mg	$205	2026-06-03	Buy
Biosynth	FD97834	2-(3,4-Difluorophenyl)ethanamine	220362-31-2	250mg	$250	2026-06-04	Buy
Biosynth	FD97834	2-(3,4-Difluorophenyl)ethanamine	220362-31-2	500mg	$385	2026-06-04	Buy
Biosynth	FD97834	2-(3,4-Difluorophenyl)ethanamine	220362-31-2	1000mg	$630	2026-06-04	Buy

Product number	Packaging	Price	Buy
L300233	50MG	$159	Buy
TRC-D451245-500MG	500mg	$205	Buy
FD97834	250mg	$250	Buy
FD97834	500mg	$385	Buy
FD97834	1000mg	$630	Buy

Benzeneethanamine, 3,4-difluoro- (9CI) Chemical Properties,Uses,Production

Synthesis

1,2-difluoro-4-[(E)-2-nitroethenyl]benzene

1025692-47-0

220362-31-2

Synthesis of intermediate 2-(3,4-difluorophenyl)ethylamine (I-49b): the preparation and post-treatment steps were carried out with reference to the preparation of intermediate I-15b. The specific operation was as follows: E-1,2-difluoro-4-(2-nitrovinyl)benzene (I-49a, 5 g, 27.027 mmol) was dissolved in anhydrous THF (81 mL), and LiBH4 (2.35 g, 108.1081 mmol) and chlorotrimethylsilane (27.63 mL, 216.216 mmol) were added sequentially at 0 °C. The reaction mixture was stirred at room temperature for 3 days. Upon completion of the reaction, 4.2 g of the target product was obtained by post-processing in 100% yield. The product was characterized by 1H NMR (DMSO, 300 MHz): δ 8.7 (broad peak, 2H), 7.5-7.3 (multiple peaks, 2H), 7.2-7.0 (multiple peaks, 1H), 3.0-2.8 (multiple peaks, 4H).LCMS analysis showed a purity of 98.87%, m/z = 158.1 (M + 1).

References

[1] Patent: US2014/45872, 2014, A1. Location in patent: Paragraph 0814
[2] Patent: WO2008/39882, 2008, A1. Location in patent: Page/Page column 191

Benzeneethanamine, 3,4-difluoro- (9CI) synthesis

Synthesis of Benzeneethanamine, 3,4-difluoro- (9CI) from 1,2-difluoro-4-[(E)-2-nitroethenyl]benzene

Benzeneethanamine, 3,4-difluoro- (9CI) Preparation Products And Raw materials

Raw materials

1,2-difluoro-4-[(E)-2-nitroethenyl]benzene Tetrahydrofuran Lithium borohydride Chlorotrimethylsilane

Preparation Products

Benzeneethanamine, 3,4-difluoro- (9CI) Suppliers

Global( 44)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14301	58
AFINE CHEMICALS LIMITED	+86-571-85134551 +86-18958018566	info@afinechem.com	China	15050	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +86-15355479329	market18@leapchem.com	China	43303	58
Aladdin Scientific		tp@aladdinsci.com	United States	50108	58
Allfluoro Pharmaceutical Company Limited	+86-400-0216110 +86-15958047586	sales@allfluoro.com	China	11380	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53799	58
NANJING YINGWEN BIOTECHNOLOGY CO LTD	+86-13382787392	sales@aeechem.com	China	10002	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
Career Henan Chemica Co	58
Win-Win chemical CO., Limited	58
AFINE CHEMICALS LIMITED	58
HANGZHOU LEAP CHEM CO., LTD.	58
Aladdin Scientific	58
Allfluoro Pharmaceutical Company Limited	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
NANJING YINGWEN BIOTECHNOLOGY CO LTD	58
Amadis Chemical Company Limited	58

View Lastest Price from Benzeneethanamine, 3,4-difluoro- (9CI) manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-22	Benzeneethanamine, 3,4-difluoro- (9CI) 220362-31-2	$1.00	1g	85.0-99.8%	20 tons	Career Henan Chemica Co

Benzeneethanamine, 3,4-difluoro- (9CI)
220362-31-2
$1.00
85.0-99.8%
Career Henan Chemica Co

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Benzeneethanamine, 3,4-difluoro- (9CI) BenzeneethanaMine, 3,4-difluoro- 2-(3,4-Difluorophenyl)ethanamine 2-(3,4-Difluorophenyl)ethylamine 3,4-Difluoro-benzeneethanaMine BENZENEETHANAMINE,3,4-DIFLUORO- (CAS NO.220362-31-2) 2-(3,4-fluorophenyl)ethanamine 2-(3,4-fluorophenyl)ethylamine 220362-31-2 22362-31-2 HALIDE