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ChemicalBook >> CAS DataBase List >>Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide

Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide

Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide Structure
Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide structure
CAS No.
1396397-03-7
Chemical Name:
Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide
Synonyms
LASSBio1366;LASSBio-1366;LASSBio 1366;Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide
CBNumber:
CB910657976
Molecular Formula:
C19H22N2O5
Molecular Weight:
358.39
MDL Number:
MOL File:
1396397-03-7.mol
MSDS File:
SDS
Last updated:2026-05-11 15:21:01
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Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide Properties

Boiling point 502.9±60.0 °C(Predicted)
Density 1.13±0.1 g/cm3(Predicted)
pka -0.08±0.70(Predicted)

Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide Chemical Properties, Uses, Production

Description

LASSBio-1366 is an adenosine A2a receptor agonist. It acts by attenuating the progression of monocrotaline-induced pulmonary hypertension.

Uses

PDE4-IN-20 is a selective submicromolar phosphodiesterase-4 (PDE4) inhibitor with anti-TNF-α properties. PDE4-IN-20 exhibits significant biological activity in vitro and in vivo. The mechanism of action of PDE4-IN-20 is supported by molecular modeling studies, which reveal its binding mode with PDE4. PDE4-IN-20 was optimized in further conformational analysis and showed pharmacological characteristics similar to those of known PDE4 inhibitors[1].

References

[1] Design, synthesis, and pharmacological evaluation of N-acylhydrazones and novel conformationally constrained compounds as selective and potent orally active phosphodiesterase-4 inhibitors

Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide Suppliers

Global Suppliers ( 4)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LASSBio-1366 pictures 2026-05-11 LASSBio-1366
1396397-03-7
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • LASSBio-1366 pictures
  • LASSBio-1366
    1396397-03-7
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.

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Benzoic acid, 3,4-dimethoxy-, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide LASSBio 1366 LASSBio1366 LASSBio-1366 1396397-03-7