3-Aminomethylbenzoic acid hydrochloride
- CAS No.
- 876-03-9
- Chemical Name:
- 3-Aminomethylbenzoic acid hydrochloride
- Synonyms
- MAMB HCL;AKOS BC-1869;3-Amb-OH·HCl;H-3-Amb-OH·HCl;3-CARBOMETHOXYBENZYLAMINE HCL;(3-carboxyphenyl)methylazanium;3-Carboxybenzylamine hydrochloride;3-(Aminomethyl)benzoicacidHClpurum;3-(AMinoMethy)benzoic acid hydrochloride;3-(AMINOMETHYL)BENZOIC ACID HYDROCHLORIDE
- CBNumber:
- CB9111284
- Molecular Formula:
- C8H10ClNO2
- Molecular Weight:
- 187.62
- MDL Number:
- MFCD03791117
- MOL File:
- 876-03-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (3-Aminomethyl) benzoic acid hydrochloride ≥99%(Assaybytitrationondriedbasis) | 07165 | 1G | $36.65 |
| (3-Aminomethyl) benzoic acid hydrochloride ≥99%(Assaybytitrationondriedbasis) | 07165 | 5G | $137.81 |
| (3-Aminomethyl) benzoic acid hydrochloride ≥99%(Assaybytitrationondriedbasis) | 07165 | 25G | $433.75 |
| (3-Aminomethyl) benzoic acid hydrochloride ≥99%(Assaybytitrationondriedbasis) | 07165 | 100G | $1207.41 |
| 3-Aminomethylbenzoic acid hydrochloride | 074446 | 1.00g | $100 |
| Melting point | 242-244℃ |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| form | Solid |
| Appearance | White to off-white Solid |
| Water Solubility | Slightly soluble in water. |
| BRN | 3697656 |
| CAS DataBase Reference | 876-03-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P280a-P304+P340-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29224999 | |||||||||
| NFPA 704 |
|
3-Aminomethylbenzoic acid hydrochloride price More Price(73)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Chem-Impex | 07165 | (3-Aminomethyl) benzoic acid hydrochloride ≥99%(Assaybytitrationondriedbasis) | 876-03-9 | 1G | $36.65 | 2026-05-19 | Buy |
| Chem-Impex | 07165 | (3-Aminomethyl) benzoic acid hydrochloride ≥99%(Assaybytitrationondriedbasis) | 876-03-9 | 5G | $137.81 | 2026-05-19 | Buy |
| Chem-Impex | 07165 | (3-Aminomethyl) benzoic acid hydrochloride ≥99%(Assaybytitrationondriedbasis) | 876-03-9 | 25G | $433.75 | 2026-05-19 | Buy |
| Chem-Impex | 07165 | (3-Aminomethyl) benzoic acid hydrochloride ≥99%(Assaybytitrationondriedbasis) | 876-03-9 | 100G | $1207.41 | 2026-05-19 | Buy |
| Matrix Scientific | 074446 | 3-Aminomethylbenzoic acid hydrochloride | 876-03-9 | 1.00g | $100 | 2026-05-18 | Buy |
3-Aminomethylbenzoic acid hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Solid
Uses
It is used as pharmaceutical intermediate. Derivatives of benzylamine and benzamidine were found to be competitive inhibitors of the proteolytic enzymes trypsin, plasmin, and thrombin.
Synthesis
1877-72-1
876-03-9
Step 6 Synthesis of 3-(aminomethyl)benzoic acid hydrochloride: 3-cyanobenzoic acid (5.88 g, 40 mmol) was suspended in 50 mL of tetrahydrofuran (THF), stirred and heated gently until completely dissolved. Subsequently, 50 mL of isopropanol was added and the solution was cooled to room temperature. To the cooled solution, 4.2 mL of pre-cooled concentrated hydrochloric acid was slowly added, followed by 300 mg of platinum(IV) oxide catalyst. The reaction mixture was subjected to hydrogenation under 55 psi hydrogen pressure overnight. Upon completion of the reaction, 50 mL of ether was added to precipitate the product, the precipitate was collected by filtration and washed with ether. The resulting solid was dissolved in methanol, filtered to remove the catalyst, and finally the solvent was removed by distillation under reduced pressure to afford 6.2 g (82% yield) of the target product 3-(aminomethyl)benzoic acid hydrochloride. The structure of the product was confirmed by 1H-NMR (DMSO-d6): δ = 4.08 (d, 2H); 7.53 (t, 1H); 7.80 (d, 1H); 7.94 (d, 1H); 8.10 (s, 1H); 8.65 (s, 3H).
References
[1] Journal of the American Chemical Society, 1994, vol. 116, # 8, p. 3220 - 3230
[2] Patent: US5635477, 1997, A
3-Aminomethylbenzoic acid hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
3-Aminomethylbenzoic acid hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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View Lastest Price from 3-Aminomethylbenzoic acid hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | 3-Aminomethylbenzoic acid hydrochloride
876-03-9
|
US $1.00 / g | 1g | 99% | 10000KGS | Career Henan Chemical Co |
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- 3-Aminomethylbenzoic acid hydrochloride
876-03-9
- US $1.00 / g
- 99%
- Career Henan Chemical Co
